Amoretti, S. Bernardo, M. Bonnin, C.M. Bioque, M. Cabrera, B. Mezquida, G. Solé, B. Vieta, E. and Torrent, C. 2017. The impact of cognitive reserve in the outcome of first-episode psychoses: 2-year follow-up study. European Neuropsychopharmacology,
Espinosa, Regina Valiente, Carmen Rigabert, Alina and Song, Hanna 2017. Recovery style and stigma in psychosis: the healing power of integrating. Cognitive Neuropsychiatry, Vol. 21, Issue. 2, p. 146.
Goodby, Emmeline and MacLeod, Andrew K. 2017. Future-directed thinking in first-episode psychosis. British Journal of Clinical Psychology, Vol. 55, Issue. 2, p. 93.
Souaiby, L. Gaillard, R. and Krebs, M.-O. 2017. Durée de psychose non traitée : état des lieux et analyse critique. L'Encéphale,
Trauelsen, Anne Marie Gumley, Andrew Jansen, Jens Einar Pedersen, Marlene Buch Nielsen, Hanne-Grethe Lyse Trier, Christopher Høier Haahr, Ulrik H. and Simonsen, Erik 2017. Metacognition in first-episode psychosis and its association with positive and negative symptom profiles. Psychiatry Research, Vol. 238, p. 14.
Yamanaka, Hiroshi Kanahara, Nobuhisa Suzuki, Tomotaka Takase, Masayuki Moriyama, Toshihiro Watanabe, Hiroyuki Hirata, Toyoaki Asano, Makoto and Iyo, Masaomi 2017. Impact of dopamine supersensitivity psychosis in treatment-resistant schizophrenia: An analysis of multi-factors predicting long-term prognosis. Schizophrenia Research, Vol. 170, Issue. 2-3, p. 252.
Austin, Stephen F. Mors, Ole Budtz-Jørgensen, Esben Secher, Rikke Gry Hjorthøj, Carsten R. Bertelsen, Mette Jeppesen, Pia Petersen, Lone Thorup, Anne and Nordentoft, Merete 2017. Long-term trajectories of positive and negative symptoms in first episode psychosis: A 10year follow-up study in the OPUS cohort. Schizophrenia Research, Vol. 168, Issue. 1-2, p. 84.
Bourdeau, Geneviève Lecomte, Tania and Lysaker, Paul H. 2017. Stages of recovery in early psychosis: Associations with symptoms, function, and narrative development. Psychology and Psychotherapy: Theory, Research and Practice, Vol. 88, Issue. 2, p. 127.
Haro, Josep Maria Altamura, Carlo Corral, Ricardo Elkis, Helio Evans, Jonathan Malla, Ashok Krebs, Marie-Odile Zink, Mathias Bernasconi, Corrado Lalonde, Justine and Nordstroem, Anna-Lena 2017. Understanding the impact of persistent symptoms in schizophrenia: Cross-sectional findings from the Pattern study. Schizophrenia Research, Vol. 169, Issue. 1-3, p. 234.
Lyne, John Joober, Ridha Schmitz, Norbert Lepage, Martin and Malla, Ashok 2017. Duration of active psychosis and first-episode psychosis negative symptoms. Early Intervention in Psychiatry, p. n/a.
Marchesi, Carlo Affaticati, Andrea Monici, Alberto De Panfilis, Chiara Ossola, Paolo Ottoni, Rebecca and Tonna, Matteo 2017. Decrease of Functioning in Remitted and Non-Remitted Patients 16 Years After a First-Episode Schizophrenia. The Journal of Nervous and Mental Disease, Vol. 203, Issue. 6, p. 406.
Revier, Camice J. Reininghaus, Ulrich Dutta, Rina Fearon, Paul Murray, Robin M. Doody, Gillian A. Croudace, Tim Dazzan, Paola Heslin, Margaret Onyejiaka, Adanna Kravariti, Eugenia Lappin, Julia Lomas, Ben Kirkbride, James B. Donoghue, Kim Morgan, Craig and Jones, Peter B. 2017. Ten-Year Outcomes of First-Episode Psychoses in the MRC ÆSOP-10 Study. The Journal of Nervous and Mental Disease, Vol. 203, Issue. 5, p. 379.
Ventura, Joseph Subotnik, Kenneth L. Gitlin, Michael J. Gretchen-Doorly, Denise Ered, Arielle Villa, Kathleen F. Hellemann, Gerhard S. and Nuechterlein, Keith H. 2017. Negative symptoms and functioning during the first year after a recent onset of schizophrenia and 8years later. Schizophrenia Research, Vol. 161, Issue. 2-3, p. 407.
Dubois, Vincent Peuskens, Joseph Geerts, Paul and Detraux, Johan 2017. Clinical outcomes of long-acting risperidone in recent versus long-term diagnosed Belgian schizophrenic patients: results from electronic Schizophrenia Treatment Adherence Registry (e-STAR) and Trial for the Initiation and Maintenance Of REmission in Schi. Early Intervention in Psychiatry, Vol. 8, Issue. 1, p. 39.
Fujii, Daryl E. and Ahmed, Iqbal 2017. Psychotic Disorder Caused by Traumatic Brain Injury. Psychiatric Clinics of North America, Vol. 37, Issue. 1, p. 113.
Lyne, J. Renwick, L. Madigan, K. O’Donoghue, B. Bonar, M. Grant, T. Kinsella, A. Malone, K. Turner, N. O’Callaghan, E. and Clarke, M. 2017. Do psychosis prodrome onset negative symptoms predict first presentation negative symptoms?. European Psychiatry, Vol. 29, Issue. 3, p. 153.
Nordon, C. Rouillon, F. Azorin, J. M. Barry, C. Urbach, M. and Falissard, B. 2017. Trajectories of antipsychotic response in drug-naive schizophrenia patients: results from the 6-month ESPASS follow-up study. Acta Psychiatrica Scandinavica, Vol. 129, Issue. 2, p. 116.
Penttila, M. Jaaskelainen, E. Hirvonen, N. Isohanni, M. and Miettunen, J. 2017. Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis. The British Journal of Psychiatry, Vol. 205, Issue. 2, p. 88.
Salokangas, R.K.R. Heinimaa, M. From, T. Löyttyniemi, E. Ilonen, T. Luutonen, S. Hietala, J. Svirskis, T. von Reventlow, H.G. Juckel, G. Linszen, D. Dingemans, P. Birchwood, M. Patterson, P. Schultze-Lutter, F. Ruhrmann, S. and Klosterkötter, J. 2017. Short-term functional outcome and premorbid adjustment in clinical high-risk patients. Results of the EPOS project. European Psychiatry, Vol. 29, Issue. 6, p. 371.
Tang, Jennifer Yee-Man Chang, Wing-Chung Hui, Christy Lai-Ming Wong, Gloria Hoi-Yan Chan, Sherry Kit-Wa Lee, Edwin Ho-Ming Yeung, Wai-Song Wong, Chi-Keung Tang, Wai-Nang Chan, Wah-Fat Pang, Edwin Pui-Fai Tso, Steve Ng, Roger Man-Kin Hung, Se-Fong Dunn, Eva Lai-Wah Sham, Pak-Chung and Chen, Eric Yu-Hai 2017. Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study. Schizophrenia Research, Vol. 153, Issue. 1-3, p. 1.
Predictors of outcome for psychosis are poorly understood. Duration of untreated psychosis (DUP) appears to predict short-term outcome although its medium- to long-term role remains unclear. Neurodevelopmental indices such as pre-morbid function and/or neurological soft signs may predict longer-term outcome. We aimed to assess the impact of a range of clinical and demographic variables on long-term outcome of a geographically defined, epidemiological first-episode psychosis cohort.
A 10-year follow-up was undertaken of a consecutively presenting sample of 109 cases of first-episode psychosis aged 16–50 years. Baseline assessments included positive, negative and depression symptoms, DUP, neurological soft signs and pre-morbid functioning. Multi-dimensional outcomes were assessed blind to baseline data.
All participants were traced at a mean of 10.5 years post-index admission: 11 had died, 10 from non-natural causes. Of the surviving cases, 70% were comprehensively re-assessed by interview. Summary data on the remainder were collected from their family practitioner and chart review. Poor 10-year outcomes were predicted independently by poor pre-morbid functioning, baseline negative symptoms and longer DUP. The same measures, plus neurological soft signs, appeared to predict outcomes in a DSM-IV schizophrenia/schizo-affective subgroup.
Poor pre-morbid functioning, baseline symptoms, DUP and neurological soft signs at onset independently predict poor long-term outcome in first-episode psychosis.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.
* Views captured on Cambridge Core between September 2016 - 21st September 2017. This data will be updated every 24 hours.