Skip to main content
×
Home
    • Aa
    • Aa

Schizophrenic syndromes, cognitive performance and neurological dysfunction

  • Peter F. Liddle (a1)
Synopsis
Synopsis

In a sample of chronic schizophrenic patients, a group of symptoms which included poverty of speech and lack of spontaneous movement was found to be associated with poor performance in tests of conceptual thinking, object naming and long-term memory, and also with cortical neurological signs. A second group of symptoms which included formal thought disorder and inappropriate affect was associated with poor performance in tests of concentration, immediate recall and word learning, and with cortical neurological signs. The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes. A third group of symptoms, comprising various delusions and hallucinations, was associated with poor figure-ground perception, and might reflect temporal lobe dysfunction.

Copyright
Corresponding author
1Address for correspondence: Dr P. F. Liddle, Charing Cross and Westminster Medical School, Academic Unit, Horton Hospital, Long Grove Road, Epsom, Surrey KT9 8PZ.
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

N. C. Andreasen & S. Olsen (1982). Negative v. positive schizophrenia. Archives of General Psychiatry 39, 789794.

T. J. Crow . (1980). Molecular pathology of schizophrenia: more than one disease process? British Medical Journal 280, 6668.

J. M. Davis (1976). Comparative doses and costs of antipsychotic medication. Archives of General Psychiatry 33, 858861.

G. Goldstein (1978), Cognitive and perceptual differences between schizophrenics and organics. Schizophrenia Bulletin 4, 160185.

G. Goldstein & K. M. Halperin (1977). Neuropsychological differences among sub-types of schizophrenia. Journal of Abnormal Psychology 86, 3440.

R. M. Hamlin (1970). Intellectual function 14 years after frontal lobe surgery. Cortex 6, 299307.

A. R. Luria (1980). Higher Cortical Functions in Man. Basic Books: New York.

P. A. Magaro (1981). The paranoid and the schizophrenic: the case for a distinct cognitive style. Schizophrenia Bulletin 7, 632661.

F. Newcombe & J. Marshall (1967). Immediate recall of sentences. Neuropsychologia 5, 329334.

F. Newcombe , R. L. Oldfield , G. G. Ratcliff & A. Wingfield (1971). Recognition and naming of object-drawings by men with focal brain wounds. Journal of Neurology, Neurosurgery and Psychiatry 34, 329340.

C. J. Pycock , R. W. Kerwin & C. J. Carter (1980). Effects of lesion of cortical dopamine terminals on sub-cortical dopamine receptors in rats. Nature (London) 286, 7477.

F. Quitkin , A. Rifkin & D. F. Klein (1976). Neurologic soft signs in schizophrenia and character disorders. Archives of General Psychiatry 33, 845853.

J. M. Rochford , T. Detre , G. J. Tucker & M. Harrow (1970). Neuropsychological impairments in functional psychiatric diseases. Archives of General Psychiatry 22, 114119.

E. Slater , A. W. Beard & E. Glitherow (1963). The schizophrenia-like psychoses of epilepsy. British Journal of Psychiatry 109, 95105.

F. T. Spellacy & O. Spreen (1969). A short form of the token test. Cortex 5, 390397.

E. K. Warrington (1974). Deficient recognition memory in organic amnesia. Cortex 10, 289291.

D. Wechsler (1958). The Measurement and Appraisal of Adult Intelligence (fourth edn). Williams and Wilkins: Baltimore.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 36 *
Loading metrics...

Abstract views

Total abstract views: 1129 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 22nd September 2017. This data will be updated every 24 hours.