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Unhappiness, health and cognitive ability in old age

  • P. Rabbitt (a1) (a2), M. Lunn (a3), S. Ibrahim (a4), M. Cobain (a5) and L. McInnes (a6)...

To test whether scores on depression inventories on entry to a longitudinal study predict mental ability over the next 4–16 years.


Associations between scores on the Beck Depression Inventory and on tests of intelligence, vocabulary and memory were analysed in 5070 volunteers aged 49–93 years after differences in prescribed drug consumption, death and drop-out, sex, socio-economic advantage and recruitment cohort effects had also been considered.


On all cognitive tasks Beck scores on entry, even in the range 0–7 indicating differences in above average contentment, affected overall levels of cognitive performance but not rates of age-related cognitive decline suggesting effects of differences in life satisfaction rather than in depression.


A new finding is that, in old age, increments in life satisfaction are associated with better cognitive performance. Implications for interpreting associations between depression inventory scores and cognitive performance in elderly samples are discussed.

Corresponding author
*Address for correspondence: Professor P. Rabbitt, Department of Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK. (Email:
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Anstey, KJ, Luszcz, MA, Giles, LC, Andrews, GR (2001). Demographic, health, cognitive and sensory variables as predictors of mortality in very old adults. Psychology and Aging 16, 311.
Austin, M-P, Mitchell, P, Goodwin, GM (2001). Cognitive deficits in depression. British Journal of Psychiatry 178, 200206.
Bassuk, SS, Berkman, LF, Wypij, D (1998). Depressive symptomatology and incident cognitive decline in an elderly community sample. Archives of General Psychiatry 55, 10731081.
Beck, AT, Ward, CH, Mendelson, M, Mock, J, Erbaugh, TG (1961). An inventory for measuring depression. Archives of General Psychiatry 4, 561571.
Blazer, D, Williams, CD (1980). Epidemiology of dysphoria and depression in an elderly population. American Journal of Psychiatry 137, 439444.
Comijs, HC, Jonker, C, Beekman, ATF, Deeg, DJD (2001). The association between depressive symptoms and cognitive decline in community-dwelling elderly. Journal of Geriatric Psychiatry 16, 361367.
Dikmen, SS, Heaton, RK, Grant, I, Temkin, NR (1999). Test-re-test reliability and practice effects of expanded Halstead-Reitan Neuropsychological Test Battery. Journal of the International Neuropsychological Society 5, 346356.
Dufouil, C, Fuhrer, R, Dartigues, J-F, Alperovitch, A (1996). Longitudinal analysis of the association between depressive symptomatology and cognitive deterioration. American Journal of Epidemiology 144, 634641.
Griffiths, RA, Good, WR, Watson, NP, O'Donnell, HF, Fell, PJ, Shakespear, JM (1987). Depression, dementia and disability in the elderly. British Journal of Psychiatry 150, 482493.
Heim, A (1970). Intelligence and Personality. Their Assessment and Relationship. Penguin Books: London.
Kucera, H, Francis, WN (1967). Computational Analysis of Present-day American English. Brown University Press: Providence, RI.
McInnes, L, Rabbitt, P (1997). The relationship between functional ability and cognitive ability among elderly people. In Facts and Research in Gerontology (ed.Vellas, B. J., Albarede, J. L. and Garry, P. J.), pp. 3445. Serdi: Paris.
Mitrushina, M, Satz, P (1991). Effect of repeated administration of a neuropsychological test battery in the elderly. Journal of Clinical Psychology 47, 790801.
Nagi, MH, Stockwell, EG (1973). Socioeconomic differentials in mortality by cause of death. Health Services Reports 88, 449456.
Norman, S, Troester, AI, Fields, JA, Brooks, R (2002). Effects of depression and Parkinson's Disease on cognitive function. Journal of Neuropsychology and Clinical Neurosciences 14, 3136.
Office of Population Censuses and Surveys (1980). Classification of Occupations 1980. HM Stationery Office: London.
Paola, AM, Troster, AI, Ryan, JJ (1997). Test-retest stability of the Californian Verbal Learning Test in older persons. Neuropsychology 11, 613616.
Rabbitt, P, Diggle, P, Holland, F, McInnes, L (2004). Practice and drop-out effects during a 17-year longitudinal study of cognitive aging. Journal of Gerontology 59B, P84P97.
Rabbitt, P, Diggle, P, Smith, D, Holland, F, McInnes, L (2001). Identifying and separating the effects of practice and of cognitive aging during a large longitudinal study of elderly community residents. Neuropsychologia 39, 532543.
Rabbitt, P, Donlan, C, Watson, P, McInnes, L, Bent, N (1995). Unique and interactive effects of depression, age, socioeconomic advantage, and gender on cognitive performance of normal healthy older people. Psychology and Aging 10, 307313.
Rabbitt, P, Lunn, M, Wong, D (2005). Neglect of dropout underestimates effects of death in longitudinal studies. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 60, P106P109.
Rabbitt, P, Lunn, M, Wong, D (in press). Death, dropout, and longitudinal measurements of cognitive change in old age. Journals of Gerontology Series B: Psychological Sciences and Social Sciences.
Raven, JC (1965). Mill Hill Vocabulary Scale. H. K. Lewis: London.
Snowden, DA, Ostwald, SK, Kane, REL, Keenan, NL (1989). Years of life with good and poor mental and physical function in the elderly. Journal of Clinical Epidemiology 42, 10551066.
Terman, LM, Oden, MH (1947). Genetic Studies of Genius, vol. 4. The gifted child grows up. Stanford University Press: Stanford, CA.
Terman, LM, Oden, MH (1959). Genetic Studies of Genius, vol. 5. The gifted group at Mid Life. Stanford University Press: Stanford, CA.
Unger, JM, van Belle, G, Heyman, A (1999). Cross-sectional versus longitudinal estimates of cognitive change in non-demented older people: a CERAD study. Journal of the American Geriatrics Society 47, 559563.
Whalley, LJ, Deary, IJ (2001). Longitudinal cohort study of childhood IQ and survival up to age 76. British Medical Journal 322, 819.
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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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