For the last few years, thanks to the Leverhulme Trust, I've been largely absent from my department, working on the late antique philosopher Plotinus. To speak personally – it's been a difficult few years, since my youngest daughter has been afflicted with anorexia during this period, and my own bowel cancer was discovered, serendipitously, and removed, at the end of 2005. Since then I've had ample occasion to consider the importance – and the difficulty – of the practice of detachment, and also to worry about the moral some have drawn from Plotinian and similar philosophies, namely that the things of this world really do not matter much, and that we should withdraw ourselves from them. Maybe it is true, as Plotinus says, that ‘some troubles are profitable to the sufferers themselves, poverty and sickness for example’. But this is not an altogether helpful message for those afflicted by the bundle of disorders that lead to anorexia. It's difficult not to suspect, for example, that Simone Weil would have lived longer but for her Neo-Platonism. It has also been made obvious to me that we are (or at any rate, I am) much less in control of our own mental and emotional states even than I had thought before. None of this, of course, should have been any surprise: I have frequently pointed out – to myself and others – the importance of distinguishing between one's self and the states one finds oneself in, and the extreme difficulty of controlling the thoughts we say are ours (but which, by that very fact, reveal themselves as very far from ours). Any delusion that my knowledge of these facts is of itself enough to render me immune to them has been – at least for the moment – thoroughly debunked – though the facts themselves are such that this disillusionment, so to call it, is probably both temporary and almost entirely insincere!