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Cannabis and Psychosis

Is there Epidemiological Evidence for an Association?

Published online by Cambridge University Press:  02 January 2018

Graham Thornicroft
Affiliation:
MRC Social and Community Psychiatry Unit, Institute of Psychiatry, De Crespigny Park, London SE5 8AF

Abstract

A review of the evidence shows that there is no convincing support for a separate clinical diagnosis of ‘cannabis psychosis'. Cannabis can, however, produce brief acute organic reactions and, in moderate to heavy doses, psychotic episodes in clear consciousness. Ingestion in naive users or increasingly heavy use in habitual users can precipitate a schizophreniform episode. Heavy users may have an increased risk of developing schizophrenia in the subsequent 15 years. Well controlled, longitudinal studies are required to explore these associations further and their possible aetiological significance.

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Papers
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Copyright © The Royal College of Psychiatrists 

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References

Altman, H. & Evenson, R. (1973) Marijuana use and subsequent psychiatric symptoms: a replication. Comprehensive Psychiatry, 14, 415420.CrossRefGoogle Scholar
Ames, F. (1958) A clinical and metabolic study of acute intoxication with cannabis sativa and its role in the model psychoses. Journal of Mental Science, 104, 972999.Google ScholarPubMed
Andreasson, S., Allebeck, P., Engstrom, A., et al (1987) Cannabis: a longitudinal study of Swedish conscripts. Lancet, ii, 14831485.CrossRefGoogle Scholar
Ashton, H. (1987) Cannabis: dangers and possible uses. British Medical Journal, 294, 141142.CrossRefGoogle ScholarPubMed
Beaubrun, M. & Knight, F. (1973) Psychiatric assessment of 30 chronic users of cannabis and 30 matched controls. American Journal of Psychiatry, 130, 309311.CrossRefGoogle ScholarPubMed
Block, R., Goneim, M., Pathak, P., et al (1988) Effect of a subanaesthetic concentration of nitrous oxide on overt and covert assessment of memory and associative processes. Psychopharmacology, 96, 324331.CrossRefGoogle Scholar
Breakey, W., Goodell, H., Lorenz, P., et al (1974) Hallucinogenic drugs as precipitants of schizophrenia. Psychological Medicine, 4, 255261.CrossRefGoogle ScholarPubMed
Cambell, A., Evans, M., Thomson, J., et al (1971) Cerebral atrophy in young cannabis smokers. Lancet, ii, 12191225.CrossRefGoogle Scholar
Cambell, I. (1976) The amotivational syndrome and cannabis use with emphasis on the Canadian scene. Annals of the New York Academy of Science, 282, 3336.CrossRefGoogle Scholar
Carney, M., Bacelle, L. & Robinson, B. (1984) Psychosis after cannabis abuse. British Medical Journal, 288, 1047.CrossRefGoogle ScholarPubMed
Chopra, G. & Smith, J. (1974) Psychotic reactions following cannabis use in East Indians. Archives of General Psychiatry, 30, 2427.CrossRefGoogle ScholarPubMed
Clark, L., Hughes, R. & Nakashika, E. (1970) Behavioral effects of marihuana. Archives of General Psychiatry, 23, 193198.CrossRefGoogle ScholarPubMed
Davison, K. & Wilson, C. (1972) Psychosis associated with cannabis smoking. British Journal of Addiction, 67, 225228.CrossRefGoogle ScholarPubMed
Dhunjibhoy, J. (1930) A brief resume of the types of insanity commonly met with in India with a full description of “Indian hemp insanity” peculiar to the country. Journal of Mental Science, 76, 254264.Google Scholar
Edwards, G. (1983) Psychopathology of a drug experience. British Journal of Psychiatry, 143, 509512.CrossRefGoogle ScholarPubMed
Estroff, T. & Gold, M. (1986) Psychiatric presentations of marijuana abuse. Psychiatric Annals, 16, 221224.CrossRefGoogle Scholar
Ghodse, A. H. (1986) Cannabis psychosis. British Journal of Addiction, 81, 487492.Google ScholarPubMed
Halikas, J., Goodwin, D. & Guze, S. (1972) Marihuana use and psychiatric illness. Archives of General Psychiatry, 27, 162165.CrossRefGoogle ScholarPubMed
Harding, T. & Knight, F. (1973) Marijuana-modified mama. Archives of General Psychiatry, 29, 635637.CrossRefGoogle Scholar
Hill, A. B. (1965) The environment and disease: association or causation? Proceedings of the Royal Society of Medicine, 295300.Google Scholar
Hollister, L. (1988) Cannabis – 1988. Acta Psychiatrica Scandinavica, 78 (suppl.), 108118.CrossRefGoogle Scholar
Indian Hemp Drugs Commission (1894) Report. Simla: IHDC.Google ScholarPubMed
Isbell, C., Gorodetzsky, C., Jasinski, D., et al (1967) Effects of (−)D9-trans-tetrahyrocannabinol in man. Psychopharmacologia, 11, 184188.CrossRefGoogle ScholarPubMed
Keeler, M., Reifler, C. B. & Liptzin, M. B. (1968) Spontaneous recurrence of marihuana effect. American Journal of Psychiatry, 111, 691696.Google Scholar
Keeler, M., (1968) Motivation for marihuana use: a correlate of adverse reaction. American Journal of Psychiatry, 125, 142146.CrossRefGoogle Scholar
Keeler, M., Ewing, J. & Rouse, B. (1971) Hallucinogenic effects of marijuana as currently used. American Journal of Psychiatry, 128, 213216.CrossRefGoogle ScholarPubMed
Keshavan, M. & Lishman, W. A. (1986) Prolonged depersonalisation following cannabis abuse. British Journal of Addiction, 81, 140141.CrossRefGoogle Scholar
Knight, F. (1976) Role of cannabis in psychiatric disturbance. Annals of the New York Academy of Science, 282, 6471.CrossRefGoogle ScholarPubMed
Knudsen, P. & Vilmar, T. (1984) Cannabis and neuroleptic agents in schizophrenia. Acta Psychiatrica Scandinavica, 69, 162174.CrossRefGoogle Scholar
Lewis, A. (1968) Cannabis. Appendix to the report by the advisory committee on drug dependence. London: HMSO.Google ScholarPubMed
Lishman, W. A. (1978) Organic Psychiatry. The Psychological Consequences of Cerebral Disorder. Oxford: Blackwell.Google Scholar
Meyer, R., Pillard, R., Shapiro, L., et al (1971) Administration of marijuana to heavy and casual marijuana users. American Journal of Psychiatry, 128, 198204.CrossRefGoogle ScholarPubMed
Negrete, J., Knapp, W., Douglas, D., et al (1986) Cannabis affects the severity of schizophrenic symptoms: results of a clinical survey. Psychological Medicine, 16, 515520.CrossRefGoogle ScholarPubMed
Palsson, A., Thulin, S. & Tunving, K. (1982) Cannabis psychosis in South Sweden. Acta Psychiatrica Scandinavica, 66, 311321.CrossRefGoogle ScholarPubMed
Renault, P., Schuster, C., Freedman, D., et al (1974) Repeat administration of marijuana smoke to humans. Archives of General Psychiatry, 31, 95102.CrossRefGoogle Scholar
Rottanburg, D., Robins, A., Ben-Arie, O., et al (1982) Cannabis-associated psychosis with hypomanic features. Lancet, ii, 13641366.CrossRefGoogle Scholar
Stefanis, C. (1978) Biological aspects of cannabis use. In The International Challenge of Drug Abuse (ed. R. C. Petersen) (monograph 19). Maryland: National Institute on Drug Abuse.Google Scholar
Symanski, H. (1981) Prolonged depersonalisation after marijuana use. American Journal of Psychiatry, 138, 231233.Google Scholar
Talbott, J. A. & Teague, J. W. (1969) Marijuana psychosis. Journal of the American Medical Association, 210, 299302.CrossRefGoogle Scholar
Tart, C. (1970) Marijuana intoxication: common experiences. Nature, 226, 701704.CrossRefGoogle ScholarPubMed
Tennant, F. (1986) The clinical syndrome of marihuana dependence. Psychiatric Annals, 16, 225234.CrossRefGoogle Scholar
Tennant, F. & Groesbeck, J. (1972) Psychiatric effects of hashish. Archives of General Psychiatry, 27, 133136.CrossRefGoogle ScholarPubMed
Thacore, V. R. (1973) Bhang psychosis. British Journal of Psychiatry, 123, 225229.CrossRefGoogle ScholarPubMed
Thacore, V. R. & Shukla, S. (1976) Cannabis psychosis and paranoid schizophrenia. Archives of General Psychiatry, 33, 383386.CrossRefGoogle ScholarPubMed
Treffert, D. (1978) Marijuana use in schizophrenia: a clear hazard. American Journal of Psychiatry, 135, 12131215.Google ScholarPubMed
Tsuang, M., Simpson, J. & Kronfol, Z. (1982) Subtypes of drug abuse with psychosis. Archives of General Psychiatry, 39, 141147.CrossRefGoogle ScholarPubMed
Tunving, K. (1985) Psychiatric effects of cannabis use. Acta Psychiatrica Scandinavica, 72, 209217.CrossRefGoogle ScholarPubMed
Warnock, J. (1903) Insanity from hasheesh. Journal of Mental Science, 49, 96110.Google Scholar
Weil, A. (1970) Adverse reactions to marihuana. New England Journal of Medicine, 282, 9971000.CrossRefGoogle ScholarPubMed
Wert, R. & Raulin, M. (1986a) The chronic cerebral effects of cannabis use. I. Methodological issues and neurological findings. International Journal of the Addictions, 21, 605628.CrossRefGoogle ScholarPubMed
Wert, R. & Raulin, M. (1986b) The chronic cerebral effects of cannabis use. II. Psychological findings and conclusions. International Journal of Addiction, 21, 629642.CrossRefGoogle ScholarPubMed
Winkler, A. (1970) Clinical and social aspects of marihuana intoxication. Archives of General Psychiatry, 23, 320325.CrossRefGoogle Scholar
Wing, J., Cooper, J. & Sartorius, N. (1974) Measurement and Classification of Psychiatric Symptoms: an Instruction Manual for PSE and CATEGO Program. Cambridge: Cambridge University Press.Google Scholar
World Health Organization (1978) Mental Disorders: Glossary and Guide to their Classification in Accordance with the Ninth Revision of the International Classification of Diseases (ICD–9). Geneva: WHO.Google Scholar
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