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  • Cited by 18
  • Cited by
    Crossref Citations
    Crossref logo
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Andres, E. Kerling, F. Hamer, H. Kasper, B. and Winterholler, M. 2017. Behavioural changes in patients with intellectual disability treated with perampanel. Acta Neurologica Scandinavica, Vol. 136, Issue. 6, p. 645.
    Shankar, R. Doran, Z. and Kerr, Mike 2016. Epilepsy and Intellectual Disabilities. p. 115.
    2009. Letters. Journal of the British Institute of Mental Handicap (APEX), Vol. 21, Issue. 3, p. 118.
    Carpay, J.A. Aalbers, K. Graveland, G.A. and Engelsman, M. 2009. Retention of new AEDs in institutionalized intellectually disabled patients with epilepsy. Seizure, Vol. 18, Issue. 2, p. 119.
    BRANFORD, D. 2008. A study of the prescribing for people with learning disabilities living in the community and in National Health Service care. Journal of Intellectual Disability Research, Vol. 38, Issue. 6, p. 577.
    BRANFORD, D. and COLLACOTT, R. A. 2008. Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities. Journal of Intellectual Disability Research, Vol. 38, Issue. 6, p. 561.
    Crawford, P Brown, S Kerr, M and Parke Davis Clinical Trials Group 2001. A randomized open-label study of gabapentin and lamotrigine in adults with learning disability and resistant epilepsy. Seizure, Vol. 10, Issue. 2, p. 107.
    Bowley, C. and Kerr, M. 2000. Epilepsy and intellectual disability. Journal of Intellectual Disability Research, Vol. 44, Issue. 5, p. 529.
    Deb, Shoumitro and Joyce, Joseph 1999. The use of antiepileptic medication in a population-based cohort of adults with learning disability and epilepsy. International Journal of Psychiatry in Clinical Practice, Vol. 3, Issue. 2, p. 129.
    Beber, Elizabeth Bailey, Nicola M and Cooper, Sally-Ann 1999. Health gain for epilepsy associated with learning disabilities psychiatric care . Irish Journal of Psychological Medicine, Vol. 16, Issue. 02, p. 46.
    Branford, D. Bhaumik, S. Duncan, F. and Collacott, R.A. 1998. A follow-up study of adults with learning disabilities and epilepsy. Seizure, Vol. 7, Issue. 6, p. 469.
    Hannah, Jean A and Brodie, Martin J 1998. Treatment of Seizures in Patients with Learning Disabilities. Pharmacology & Therapeutics, Vol. 78, Issue. 1, p. 1.
    Hannah, Jean A. and Brodie, Martin J. 1998. Epilepsy and learning disabilities—a challenge for the next millennium?. Seizure, Vol. 7, Issue. 1, p. 3.
    Bhaumik, S. Branford, D. Duggirala, C. and Ismail, I.A. 1997. A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. Seizure, Vol. 6, Issue. 2, p. 127.
    Nichols, K. R. Prasher, V. P. Krishnan, V. H. R. Boughey, J. and Londhe, R. P. 1994. EPILEPSY IN A MENTAL HANDICAP HOSPITAL: A SURVEY REPORT. The British Journal of Development Disabilities, Vol. 40, Issue. 78, p. 54.
    Deb, S. and Hunter, D. 1992. The effect of anticonvulsant medication on the psychopathology of adults with a mental handicap and epilepsy. Human Psychopharmacology: Clinical and Experimental, Vol. 7, Issue. 2, p. 129.
    May, T. W. Bulmahn, A. Wohlhüter, M. and Rambeck, B. 1992. Effects of withdrawal of phenytoin on cognitive and psychomotor functions in hospitalized epileptic patients on polytherapy. Acta Neurologica Scandinavica, Vol. 86, Issue. 2, p. 165.
    Hanzel, Thomas E. Kalachnik, John E. and Harder, Stuart R. 1992. A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy. Research in Developmental Disabilities, Vol. 13, Issue. 4, p. 381.
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Clinical and Therapeutic Monitoring of Epilepsy in a Mental Handicap Unit

  • R. A. Collacott (a1), A. Dignon (a2), A. Hauck (a2) and J. W. Ward (a2)
Abstract

Within a group of hospitals for the mentally handicapped serving the Leicestershire district, a cohort of 215 epileptic patients was identified, who were followed up for four years. The anticonvulsant medication of each patient was reviewed regularly until an optimal balance between seizure control, absence of medication side-effects, and reduction of polypharmacy was attained. After four years 172 patients remained in the study. A significant reduction in polypharmacy was attained overall. Some groups of patients showed a significant reduction in the frequency of seizures, while a small group of patients with frequent seizures remained difficult to control.

Copyright
COPYRIGHT: © Royal College of Psychiatrists 1989 
Corresponding author
∗ Leicester Frith Hospital, Groby Road, Leicester LE3 9QF
References
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  • Cited by 18
  • Cited by
    Crossref Citations
    Crossref logo
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Andres, E. Kerling, F. Hamer, H. Kasper, B. and Winterholler, M. 2017. Behavioural changes in patients with intellectual disability treated with perampanel. Acta Neurologica Scandinavica, Vol. 136, Issue. 6, p. 645.
    Shankar, R. Doran, Z. and Kerr, Mike 2016. Epilepsy and Intellectual Disabilities. p. 115.
    2009. Letters. Journal of the British Institute of Mental Handicap (APEX), Vol. 21, Issue. 3, p. 118.
    Carpay, J.A. Aalbers, K. Graveland, G.A. and Engelsman, M. 2009. Retention of new AEDs in institutionalized intellectually disabled patients with epilepsy. Seizure, Vol. 18, Issue. 2, p. 119.
    BRANFORD, D. 2008. A study of the prescribing for people with learning disabilities living in the community and in National Health Service care. Journal of Intellectual Disability Research, Vol. 38, Issue. 6, p. 577.
    BRANFORD, D. and COLLACOTT, R. A. 2008. Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities. Journal of Intellectual Disability Research, Vol. 38, Issue. 6, p. 561.
    Crawford, P Brown, S Kerr, M and Parke Davis Clinical Trials Group 2001. A randomized open-label study of gabapentin and lamotrigine in adults with learning disability and resistant epilepsy. Seizure, Vol. 10, Issue. 2, p. 107.
    Bowley, C. and Kerr, M. 2000. Epilepsy and intellectual disability. Journal of Intellectual Disability Research, Vol. 44, Issue. 5, p. 529.
    Deb, Shoumitro and Joyce, Joseph 1999. The use of antiepileptic medication in a population-based cohort of adults with learning disability and epilepsy. International Journal of Psychiatry in Clinical Practice, Vol. 3, Issue. 2, p. 129.
    Beber, Elizabeth Bailey, Nicola M and Cooper, Sally-Ann 1999. Health gain for epilepsy associated with learning disabilities psychiatric care . Irish Journal of Psychological Medicine, Vol. 16, Issue. 02, p. 46.
    Branford, D. Bhaumik, S. Duncan, F. and Collacott, R.A. 1998. A follow-up study of adults with learning disabilities and epilepsy. Seizure, Vol. 7, Issue. 6, p. 469.
    Hannah, Jean A and Brodie, Martin J 1998. Treatment of Seizures in Patients with Learning Disabilities. Pharmacology & Therapeutics, Vol. 78, Issue. 1, p. 1.
    Hannah, Jean A. and Brodie, Martin J. 1998. Epilepsy and learning disabilities—a challenge for the next millennium?. Seizure, Vol. 7, Issue. 1, p. 3.
    Bhaumik, S. Branford, D. Duggirala, C. and Ismail, I.A. 1997. A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities. Seizure, Vol. 6, Issue. 2, p. 127.
    Nichols, K. R. Prasher, V. P. Krishnan, V. H. R. Boughey, J. and Londhe, R. P. 1994. EPILEPSY IN A MENTAL HANDICAP HOSPITAL: A SURVEY REPORT. The British Journal of Development Disabilities, Vol. 40, Issue. 78, p. 54.
    Deb, S. and Hunter, D. 1992. The effect of anticonvulsant medication on the psychopathology of adults with a mental handicap and epilepsy. Human Psychopharmacology: Clinical and Experimental, Vol. 7, Issue. 2, p. 129.
    May, T. W. Bulmahn, A. Wohlhüter, M. and Rambeck, B. 1992. Effects of withdrawal of phenytoin on cognitive and psychomotor functions in hospitalized epileptic patients on polytherapy. Acta Neurologica Scandinavica, Vol. 86, Issue. 2, p. 165.
    Hanzel, Thomas E. Kalachnik, John E. and Harder, Stuart R. 1992. A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy. Research in Developmental Disabilities, Vol. 13, Issue. 4, p. 381.
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  • Get access
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Clinical and Therapeutic Monitoring of Epilepsy in a Mental Handicap Unit

  • R. A. Collacott (a1), A. Dignon (a2), A. Hauck (a2) and J. W. Ward (a2)
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