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Cognitive–behavioural therapy for chronic fatigue syndrome: neither efficacious nor safe

  • Frank Twisk (a1) and Lou Corsius (a2)
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1Janse, A, Worm-Smeitink, M, Bleijenberg, G, Donders, R, Knoop, H. Efficacy of web-based cognitive-behavioural therapy for chronic fatigue syndrome: randomised controlled trial. Br J Psychiatry 2018; 212: 112–8.
2Twisk, FNM, Corsius, LAMM. An analysis of Dutch hallmark studies confirms the outcome of the PACE trial: cognitive behaviour therapy with a graded activity protocol is not effective for chronic fatigue syndrome and myalgic encephalomyelitis. Gen Med Open 2017; 1: 113.
3Sunnquist, M, Jason, LA, Nehrke, P, Goudsmit, EM. A comparison of case definitions for myalgic encephalomyelitis and chronic fatigue syndrome. J Chronic Dis Manag 2017; 2: pii:1013.
4Cheshire, A, Ridge, D, Clark, L, White, P. Why patients with chronic fatigue syndrome/myalgic encephalomyelitis improve or deteriorate with graded exercise therapy. J Psychosom Res 2016; 85: 59.
5Twisk, F. Studies and surveys implicate potential iatrogenic harm of cognitive behavioral therapy and graded exercise therapy for myalgic encephalomyelitis and chronic fatigue syndrome patients. Res Chronic Dis 2017; 1: 13–4.

Cognitive–behavioural therapy for chronic fatigue syndrome: neither efficacious nor safe

  • Frank Twisk (a1) and Lou Corsius (a2)

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