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A disabling combination: fatigue and depression

  • Stephanie S. Leone (a1)
Abstract
Summary

Fatigue and common psychiatric symptoms – depression in particular – have consistently been found to be strongly associated. All have a negative impact on functional status, but evidence suggests that functional impairment is especially marked when they co-occur. Therefore, it is pertinent to understand the relationship between fatigue and depression.

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References
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1 Afari, N, Buchwald, D. Chronic fatigue syndrome: a review. Am J Psychiatry 2003; 160: 221–36.
2 Skapinakis, P, Lewis, G, Mavreas, V. Unexplained fatigue syndromes in a multinational primary care sample: specificity of definition and prevalence and distinctiveness from depression and generalized anxiety. Am J Psychiatry 2003; 160: 785–7.
3 Skapinakis, P, Lewis, G, Meltzer, H. Clarifying the relationship between unexplained chronic fatigue and psychiatric morbidity: results from a community survey in Great Britain. Int Rev Psychiatry 2003; 15: 5764.
4 Ball, HA, Sumathipala, A, Siribaddana, SH, Kovas, Y, Glozier, N, McGuffin, P et al. Aetiology of fatigue in Sri Lanka and its overlap with depression. Br J Psychiatry 2010; 197: 106113.
5 Ross, SD, Estok, RP, Frame, D, Stone, LR, Ludensky, V, Levine, CB. Disability and chronic fatigue syndrome: a focus on function. Arch Intern Med 2004; 164: 1098–107.
6 Cairns, R Hotopf, M. A systematic review describing the prognosis of chronic fatigue syndrome. Occup Med 2005; 55: 2031.
7 Parker, AJ, Wessely, S, Cleare, AJ. The neuroendocrinology of chronic fatigue syndrome and fibromyalgia. Psychol Med 2001; 31: 1331–45.
8 Hickie, I, Kirk, K, Martin, N. Unique genetic and environmental determinants of prolonged fatigue: a twin study. Psychol Med 1999; 29: 259–68.
9 Harvey, SB, Wessely, S, Kuh, D, Hotopf, M. The relationship between fatigue and psychiatric disorders: evidence for the concept of neurasthenia. J Psychosom Res 2009; 66: 445–54.
10 Harvey, SB, Wadsworth, M, Wessely, S, Hotopf, M. The relationship between prior psychiatric disorder and chronic fatigue: evidence from a national birth cohort study. Psychol Med 2008; 38: 933–40.
11 Huibers, MJH, Leone, SS, van Amelsvoort, LGPM, Kant, I, Knottnerus, JA. Associations of fatigue and depression among fatigued employees over time: a 4-year follow-up study. J Psychosom Res 2007; 63: 137–42.
12 Skapinakis, P, Lewis, G, Mavreas, V. Temporal relations between unexplained fatigue and depression: longitudinal data from an international study in primary care. Psychosom Med 2004; 66: 330–5.
13 Hickie, I, Davenport, T, Vernon, SD, Nisenbaum, RR, Reeves, WC, Hadzi-Pavlovic, D et al. Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and health-care settings? Aust N Z J Psychiatry 2009; 43: 2535.
14 Skapinakis, P, Lewis, G, Mavreas, V. Cross-cultural differences in the epidemiology of unexplained fatigue syndromes in primary care. Br J Psychiatry 2003; 182: 205–9.
15 Cho, HJ, Menezes, PR, Hotopf, M, Bhugra, D, Wessely, S. Comparative epidemiology of chronic fatigue syndrome in Brazilian and British primary care: prevalence and recognition. Br J Psychiatry 2009; 194: 117–22.
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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A disabling combination: fatigue and depression

  • Stephanie S. Leone (a1)
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