McGrath, J, Saha, S, Chant, D, Welham, J. Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev
2008; 30: 67–76.
Saha, S, Chant, D, McGrath, J. Meta-analyses of the incidence and prevalence of schizophrenia: conceptual and methodological issues. Int J Methods Psychiatr Res
2008; 17: 55–61.
Saha, S, Chant, DC, Welham, JL, McGrath, JJ. The incidence and prevalence of schizophrenia varies with latitude. Acta Psychiatr Scand
2006; 114: 36–9.
Saha, S, Chant, DC, Welham, JL, McGrath, JJ. Incidence of schizophrenia does not vary with economic status of the country. Evidence from a systematic review. Soc Psychiatry Psychiatr Epidemiol
2006; 41: 338–40.
Faraone, SV, Chen, WJ, Goldstein, JM, Tsuang, MT. Gender differences in age at onset of schizophrenia. Br J Psychiatry
1994; 164: 625–9.
Häfner, H, an der Heiden, W, Behrens, S, Gattaz, WF, Hambrecht, M, Löffler, W, et al. Causes and consequences of the gender difference in age at onset of schizophrenia. Schizoph Bull
1998; 24: 99–113.
Aleman, A, Kahn, RS, Selten, JP. Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch Gen Psychiatry
2003; 60: 565–71.
Kirkbride, JB, Fearon, P, Morgan, C, Dazzan, P, Morgan, K, Tarrant, J, et al. Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AESOP study. Arch Gen Psychiatry
2006; 63: 250–8.
Crebbin, K, Mitford, E, Paxton, R, Turkington, D. First-episode psychosis: an epidemiological survey comparing psychotic depression with schizophrenia. J Affect Disord
2008; 105: 117–24.
Coid, JW, Kirkbride, JB, Barker, D, Cowden, F, Stamps, R, Yang, M, et al. Raised incidence rates of all psychoses among migrant groups: findings from the East London first episode psychosis study. Arch Gen Psychiatry
2008; 65: 1250–8.
van Os, J, Takei, N, Castle, DJ, Wessely, S, Der, G, MacDonald, AM, et al. The incidence of mania: time trends in relation to gender and ethnicity. Soc Psychiatry Psychiatr Epidemiol
1996; 31: 129–36.
Lloyd, T, Jones, PB. The epidemiology of first-onset mania. In Textbook of Psychiatric Epidemiology (2nd edn) (eds Tsuang, MT, Tohen, M): 445–58. Wiley-Liss, 2002.
Kennedy, N, Boydell, J, Kalidindi, S, Fearon, P, Jones, PB, van Os, J, et al. Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, England. Am J Psychiatry
2005; 162: 257–62.
Cantor-Graae, E, Selten, JP. Schizophrenia and migration: a meta-analysis and review. Am J Psychiatry
2005; 162: 12–24.
Bourque, F, van der Ven, E, Malla, A. A meta-analysis of the risk for psychotic disorders among first- and second-generation immigrants. Psychol Med
2011; 41: 897–910.
Selten, JP, Veen, N, Feller, W, Blom, JD, Khan, R, Schols, D, et al. Incidence of psychotic disorders in immigrant groups to The Netherlands. Br J Psychiatry
2001; 178: 367–72.
Cantor-Graae, E, Pedersen, CB. Risk of schizophrenia in second-generation immigrants: a Danish population-based cohort study. Psychol Med
2007; 37: 485–94.
Veling, W, Susser, E, van Os, J, Mackenbach, JP, Selten, JP, Hoek, HW. Ethnic density of neighborhoods and incidence of psychotic disorders among immigrants. Am J Psychiatry
2008; 165: 66–73.
Harrison, G, Glazebrook, C, Brewin, J, Cantwell, R, Dalkin, T, Fox, R, et al. Increased incidence of psychotic disorders in migrants from the Caribbean to the United Kingdom. Psychol Med
1997; 27: 799–806.
Fearon, P, Kirkbride, JB, Morgan, C, Dazzan, P, Morgan, K, Lloyd, T, et al. Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study. Psychol Med
2006; 36: 1541–50.
van Os, J. Does the urban environment cause psychosis?
Br J Psychiatry
2004; 184: 287–8.
Krabbendam, L, van Os, J. Schizophrenia and urbanicity: a major environmental influence – conditional on genetic risk. Schizophr Bull
2005; 31: 795–9.
McGrath, J, Scott, J. Urban birth and risk of schizophrenia: a worrying example of epidemiology where the data are stronger than the hypotheses. Epidemiol Psichiatr Soc
2006; 15: 243–6.
Allardyce, J, Boydell, J. Review: the wider social environment and schizophrenia. Schizophr Bull
2006; 32: 592–8.
Croudace, TJ, Kayne, R, Jones, PB, Harrison, GL. Non-linear relationship between an index of social deprivation, psychiatric admission prevalence and the incidence of psychosis. Psychol Med
2000; 30: 177–85.
Kirkbride, JB, Morgan, C, Fearon, P, Dazzan, P, Murray, RM, Jones, PB. Neighbourhood-level effects on psychoses: re-examining the role of context. Psychol Med
2007; 37: 1413–25.
Burns, JK, Esterhuizen, T. Poverty, inequality and the treated incidence of first-episode psychosis: an ecological study from South Africa. Soc Psychiatry Psychiatr Epidemiol
2008; 43: 331–5.
Zammit, S, Lewis, G, Rasbash, J, Dalman, C, Gustafsson, JE, Allebeck, P. Individuals, schools, and neighborhood: a multilevel longitudinal study of variation in incidence of psychotic disorders. Arch Gen Psychiatry
2010; 67: 914–22.
Pelayo-Terán, JM, Pérez-Iglesias, R, Ramírez-Bonilla, M, González-Blanch, C, Martínez-García, O, Pardo-García, G, et al. Epidemiological factors associated with treated incidence of first-episode non-affective psychosis in Cantabria: insights from the Clinical Programme on Early Phases of Psychosis. Early Interv Psychiatry
2008; 2: 178–87.
De Salvia, D, Barbato, A, Salvo, P, Zadro, F. Prevalence and incidence of schizophrenic disorders in Portogruaro. An Italian case register study. J Nerv Ment Dis
1993; 181: 275–82.
Balestrieri, M, Rucci, P, Nicolaou, S. Gender-specific decline and seasonality of births in operationally defined schizophrenics in Italy. Schizophr Res
1997; 27: 73–81.
Preti, A, Miotto, P. Increase in first admissions for schizophrenia and other major psychoses in Italy. Psychiatry Res
2000; 94: 139–52.
Tarricone, I, Mimmi, S, Paparelli, A, Rossi, E, Mori, E, Panigada, S, et al. First-episode psychosis at the West Bologna Community Mental Health Centre: results of an 8-year prospective study. Psychol Med
2012; 42: 2255–64.
Kirkbride, JB, Errazuriz, A, Croudace, TJ, Morgan, C, Jackson, D, Boydell, J, et al. Incidence of schizophrenia and other psychoses in England, 1950–2009: a systematic review and meta-analyses. PLoS One
2012; 7: e31660.
Jablensky, A. The epidemiological horizon. In Schizophrenia (2nd edn) (eds Hirsch, SR, Weinberger, D): 203–31. Blackwell Publishing, 2003.
Bertani, M, Lasalvia, A, Bonetto, C, Tosato, S, Cristofalo, D, Bissoli, S, et al. The influence of gender on clinical and social characteristics of patients at psychosis onset: a report from the Psychosis Incident Cohort Outcome Study (PICOS). Psychol Med
2012; 42: 769–82.
Lasalvia, A, Tosato, S, Brambilla, P, Bertani, M, Bonetto, C, Cristofalo, D, et al. A multisite study of clinical, social and biological characteristics, patterns of care and predictors of outcome in first-episode psychosis. Background, methodology and overview of the patient sample. Epidemiol Psychiatr Sci
2012; 21: 281–303.
Jablensky, A, Sartorius, N, Ernberg, G, Anker, M, Korten, A, Cooper, JE, et al. Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl
1992; 20: 1–97.
World Health Organization. Schedule for Clinical Assessment in Neuropsychiatry. WHO, 1992.
World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. WHO, 1992.
Istituto Nazionale di Statistica. ISTAT Atlante Statistico dei Comuni (Edizione 2009). ISTAT, 2009.
Tello, JE, Mazzi, M, Tansella, M, Bonizzato, P, Jones, J, Amaddeo, F. Does socioeconomic status affect the use of community-based psychiatric services? A south Verona case register study. Acta Psychiatr Scand
2005; 112: 215–23.
Donisi, V, Jones, J, Pertile, R, Salazzari, D, Grigoletti, L, Tansella, M, et al. The difficult task of predicting the costs of community-based mental health care. A comprehensive case register study. Epidemiol Psychiatr Sci
2011; 20: 245–56.
McGrath, J, Saha, S, Welham, J, El Saadi, O, MacCauley, C, Chant, D. A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med
2004; 2: 13.
Sherazi, R, McKeon, P, McDonough, M, Daly, I, Kennedy, N. What's new? The clinical epidemiology of bipolar I disorder. In Harv Rev Psychiatry
2000; 14: 273–84.
Mortensen, PB, Pedersen, CB, Melbye, M, Mors, O, Ewald, H. Individual and familial risk factors for bipolar affective disorders in Denmark. Arch Gen Psychiatry
2003; 60: 1209–15.
Brewin, J, Cantwell, R, Dalkin, T, Fox, R, Medley, I, Glazebrook, C, et al. Incidence of schizophrenia in Nottingham. A comparison of two cohorts, 1978–80 and 1992–94. Br J Psychiatry
1997; 171: 140–4.
Scully, PJ, Quinn, JF, Morgan, MG, Kinsella, A, O'Callaghan, E, Owens, JM, et al. First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: incidence and gender in the Cavan–Monaghan study at 5 years. Br J Psychiatry
2002; 181 (suppl 43): 3–9.
Lloyd, T, Kennedy, N, Fearon, P, Kirkbride, J, Mallett, R, Leff, J, et al. Incidence of bipolar affective disorder in three UK cities. Results from the AESOP study. Br J Psychiatry
2005; 186: 126–31.
Harrison, G, Cooper, JE, Gancarczyk, R. Changes in the administrative incidence of schizophrenia. Br J Psychiatry
1991; 159: 811–6.
Castle, D, Wessely, S, Der, G, Murray, RM. The incidence of operationally defined schizophrenia in Camberwell, 1965–84. Br J Psychiatry
1991; 159: 790–4.
Bamrah, JS, Freeman, HL, Goldberg, DP. Epidemiology of schizophrenia in Salford, 1974–84. Changes in an urban community over ten years. Br J Psychiatry
1991; 159: 802–10.
Amaddeo, F, Zambello, F, Tansella, M, Thornicroft, G. Accessibility and pathways to psychiatric care in a community-based mental health system. Soc Psychiatry Psychiatr Epidemiol
2001; 36: 500–7.
Kirkbride, JB, Jones, PB, Ullrich, S, Coid, JW. Social deprivation, inequality, and the neighborhood-level incidence of psychotic syndromes in East London. Schizophr Bull
2014; 40: 169–80.
Tansella, M, Balestrieri, M, Meneghelli, M, Micciolo, R. Trends in the provision of psychiatric care 1979–1988. In Community-Based Psychiatry Long-Term Patterns of Care in South-Verona. Psychological Medicine Monograph Supplement 19 (ed. Tansella, M): 1–54. Cambridge University Press, 1991.
Leão, TS, Sundquist, J, Frank, G, Johansson, LM, Johansson, SE, Sundquist, K. Incidence of schizophrenia or other psychoses in first- and second-generation immigrants: a national cohort study. J Nerv Ment Dis
2006; 194: 27–33.
Cheng, F, Kirkbride, JB, Lennox, BR, Perez, J, Masson, K, Lawrence, K, et al. Administrative incidence of psychosis assessed in an early intervention service in England: first epidemiological evidence from a diverse, rural and urban setting. Psychol Med
2011; 41: 949–58.
Kirkbride, JB, Stubbins, C, Jones, PB. Psychosis incidence through the prism of early intervention services. Br J Psychiatry
2012; 200: 156–7.
Svedberg, B, Mesterton, A, Cullberg, J. First-episode non-affective psychosis in a total urban population: a 5-year follow-up. Soc Psychiatry Psychiatr Epidemiol
2001; 36: 332–7.
Welham, JL, Thomis, RJ, McGrath, JJ. Age-at-first-registration for affective psychosis and schizophrenia. Schizophr Bull
2004; 30: 849–53.
Edwards, J, Harris, MG, Bapat, S. Developing services for first-episode psychosis and the critical period. Br J Psychiatry
2005; 187 (suppl 48): 91–7.
Bhugra, D, Leff, J, Mallett, R, Der, G, Corridan, B, Rudge, S. Incidence and outcome of schizophrenia in Whites, African-Caribbeans and Asians in London. Psychol Med
1997; 27: 791–8.
Mahy, GE, Mallett, R, Leff, J, Bhugra, D. First-contact incidence rate of schizophrenia on Barbados. Br J Psychiatry
1999; 175: 28–33.
Selten, JP, Cantor-Graae, E, Kahn, RS. Migration and schizophrenia. Curr Opin Psychiatry
2007; 20: 111–5.
Kaymaz, N, Krabbendam, L, de Graaf, R, Nolen, W, Ten Have, M, van Os, J. Evidence that the urban environment specifically impacts on the psychotic but not the affective dimension of bipolar disorder. Soc Psychiatry Psychiatr Epidemiol
2006; 41: 679–85.
Thornicroft, G, Bisoffi, G, De Salvia, D, Tansella, M. Urban-rural differences in the associations between social deprivation and psychiatric service utilisation in schizophrenia and all diagnoses: a case-register study in Northern Italy. Psychol Med
1993; 23: 487–96.
Pedersen, CB, Mortensen, PB. Urbanicity during upbringing and bipolar affective disorders in Denmark. Bipolar Disord
2006; 8: 242–7.
Lichtenstein, P, Yip, BH, Björk, C, Pawitan, Y, Cannon, TD, Sullivan, PF, Hultman, CM. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet
2009; 373: 234–9.
European Network of Schizophrenia Networks for the Study of Gene-Environment Interactions. Schizophrenia aetiology: do gene-environment interactions hold the key?
2008; 102: 21–6.