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Outcome of major depression in Ethiopia: Population-based study

  • Souci Mogga (a1), Martin Prince (a1), Atalay Alem (a2), Derege Kebede (a3), Robert Stewart (a1), Nick Glozier (a1) and Matthew Hotopf (a1)...

Abstract

Background

The outcome and impact of major depression in developing countries are not clear.

Aims

To describe the outcome of major depression and compare the disability and patterns of service use among different outcome groups.

Method

In a case cohort study, nested within a population-based survey of 68 000 participants using the Composite International Diagnostic Interview (CIDI), 300 participants were randomly selected from those with current major depression and 300 from those with no lifetime history. Participants were re-interviewed after 18–62 months to ascertain current diagnosis, psychological symptoms, disability and use of health services.

Results

Of participants with major depression at baseline 26% also met criteria for major depression at follow up. Mortality ratio standardised for age and gender was 3.55 (95% CI 1.97 to 6.39). All indices of measure of disability were significantly higher in the persistently depressed group compared with the completely recovered group. Participants who had recovered partially resembled participants with persistent depression. Two-thirds of those with persistent depression had not sought any help.

Conclusions

Major depression was associated with mortality and disability Those with residual symptoms remained disabled. Help-seeking was unusual.

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Copyright

Corresponding author

Dr Souci Mogga Frissa, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK. Email: S.Frissa@iop.kcl.ac.uk

Footnotes

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Declaration of interest

None.

Funding detailed in Acknowledgements.

Footnotes

References

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  • ISSN: 0007-1250
  • EISSN: 1472-1465
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Outcome of major depression in Ethiopia: Population-based study

  • Souci Mogga (a1), Martin Prince (a1), Atalay Alem (a2), Derege Kebede (a3), Robert Stewart (a1), Nick Glozier (a1) and Matthew Hotopf (a1)...
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