Skip to main content
×
×
Home

Pathological gambling: a neurobiological and clinical update

  • Henrietta Bowden-Jones (a1) and Luke Clark (a2)
Summary

A proposed merging of pathological gambling with the drug addictions in the forthcoming DSM-5 prompts an overview of the neurobiological data showing similarities between these conditions, as well as an update on national trends in gambling behaviour and current treatment provision.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Pathological gambling: a neurobiological and clinical update
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Pathological gambling: a neurobiological and clinical update
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Pathological gambling: a neurobiological and clinical update
      Available formats
      ×
Copyright
Corresponding author
Dr Henrietta Bowden-Jones, National Problem Gambling Clinic, 1 Frith Street, London W1D 3HZ, UK. Email: h.bowdenjones02@imperial.ac.uk
Footnotes
Hide All

H.B.-J. and L.C. have received funding from the Medical Research Council (grant G0802725). L.C. also receives grant funding from the Royal Society for research into the brain mechanisms of problem gambling. The National Problem Gambling Clinic is funded by the government's Responsible Gambling Fund.

Declaration of interest

H. B-J. is Founder and Director of the National Problem Gambling Clinic, is a member of the government's Responsible Gambling Strategy Board and the spokesperson on problem gambling for the Royal College of Psychiatrists.

Footnotes
References
Hide All
1 Holden, C. Behavioral addictions debut in proposed DSM-V. Science 2010; 327: 935.
2 Mitzner, GB, Whelan, JP, Meyers, AW. Comments from the trenches: proposed changes to the DSM-V classification of pathological gambling. J Gambl Stud 2010; Oct 24 (Epub ahead of print).
3 Potenza, MN. Should addictive disorders include non-substance-related conditions? Addiction 2006; 101 (Suppl 1): 142–51.
4 Petry, NM, Stinson, FS, Grant, BF. Comorbidity of DSM-IV pathological gambling and other psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2005; 66: 564–74.
5 Clark, L. Decision-making during gambling: an integration of cognitive and psychobiological approaches. Philos Trans R Soc Lond B Biol Sci 2010; 365: 319–30.
6 Grant, JE, Kim, SW, Hartman, BK. A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges. J Clin Psychiatry 2008; 69: 783–9.
7 Lawrence, AJ, Luty, J, Bogdan, NA, Sahakian, BJ, Clark, L. Problem gamblers share deficits in impulsive decision-making with alcohol-dependent individuals. Addiction 2009; 104: 1006–15.
8 Petry, NM. Pathological gamblers, with and without substance use disorders, discount delayed rewards at high rates. J Abnorm Psychol 2001; 110: 482–7.
9 Goudriaan, AE, Oosterlaan, J, de Beurs, E, van den Brink, W. Neurocognitive functions in pathological gambling: a comparison with alcohol dependence, Tourette syndrome and normal controls. Addiction 2006; 101: 534–47.
10 Bowden-Jones, H, McPhillips, M, Rogers, R, Hutton, S, Joyce, E. Risk-taking on tests sensitive to ventromedial prefrontal cortex dysfunction predicts early relapse in alcohol dependency: a pilot study. J Neuropsychiatry Clin Neurosci 2005; 17: 417–20.
11 Potenza, MN. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond B Biol Sci 2008; 363: 3181–9.
12 Reuter, J, Raedler, T, Rose, M, Hand, I, Glascher, J, Buchel, C. Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat Neurosci 2005; 8: 147–8.
13 Campbell-Meiklejohn, DK, Woolrich, MW, Passingham, RE, Rogers, RD. Knowing when to stop: the brain mechanisms of chasing losses. Biol Psychiatry 2008; 63: 293300.
14 Blaszczynski, A, Nower, L. A pathways model of problem and pathological gambling. Addiction 2002; 97: 487–99.
15 Toce-Gerstein, M, Gerstein, DR, Volberg, RA. A hierarchy of gambling disorders in the community. Addiction 2003; 98: 1661–72.
16 Wardle, H, Sproston, K, Erens, B, Orford, J, Griffiths, M, Constantine, R, et al. British Gambling Prevalence Survey 2007. National Centre for Social Research, 2007.
17 Strong, DR, Kahler, CW. Evaluation of the continuum of gambling problems using the DSM-IV. Addiction 2007; 102: 713–21.
18 Kessler, RC, Hwang, I, LaBrie, R, Petukhova, M, Sampson, NA, Winters, KC, et al. DSM-IV pathological gambling in the National Comorbidity Survey Replication. Psychol Med 2008; 38: 1351–60.
19 Shaffer, HJ, Hall, MN, Vander Bilt, J. Estimating the prevalence of disordered gambling behavior in the United States and Canada: a research synthesis. Am J Public Health 1999; 89: 1369–76.
20 Wardle, H, Moody, A, Spence, S, Orford, J, Volberg, R, Jotangia, D, et al. British Gambling Prevalence Survey 2010. National Centre for Social Research, 2011.
21 Gooding, P, Tarrier, N. A systematic review and meta-analysis of cognitive-behavioural interventions to reduce problem gambling: hedging our bets? Behav Res Ther 2009; 47: 592607.
22 Block, JJ. Issues for DSM-V: internet addiction. Am J Psychiatry 2008; 165: 306–7.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 25 *
Loading metrics...

Abstract views

Total abstract views: 698 *
Loading metrics...

* Views captured on Cambridge Core between 3rd January 2018 - 25th April 2018. This data will be updated every 24 hours.

Pathological gambling: a neurobiological and clinical update

  • Henrietta Bowden-Jones (a1) and Luke Clark (a2)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *