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Patient education to encourage graded exercise in chronic fatigue syndrome: 2-year follow-up of randomised controlled trial

  • Pauline Powell (a1), Richard P. Bentall (a1), Fred J. Nye (a1) and Richard H. T. Edwards (a1)
Abstract
Background

An earlier trial demonstrated good outcomes after 1 year for patients with chronic fatigue syndrome (CFS) who received an educational intervention designed to encourage graded activity.

Aims

To determine 2-year outcomes for the same treated patients and the response to treatment of patients formerly in the control condition.

Method

Patients in the treatment groups (n=114) were followed up at 2 years; 32 patients from the control group were offered the intervention after 1 year and were assessed 1 year later. Assessments were the self-rated measures used in the original trial.

Results

At 2 years 63 of the treated patients (55%) no longer fulfilled trial criteria for CFS compared with 64 patients (56%) at 1 year. Fourteen of 30 crossover patients (47%) achieved a good outcome at 1 year and seven (23%) no longer fulfilled criteria for CFS.

Conclusions

Benefits of the intervention were maintained at 2 years. Delaying treatment is associated with reduced efficacy and required more intensive therapy.

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Copyright
Corresponding author
Professor Richard Bentall, Department of Psychology, University of Manchester, Oxford Road, Manchester M13 9PL, UK. E-mail: bentall@psy.man.ac.uk
Footnotes
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Declaration of interest

None. Funding detailed in Acknowledgements.

Footnotes
References
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Patient education to encourage graded exercise in chronic fatigue syndrome: 2-year follow-up of randomised controlled trial

  • Pauline Powell (a1), Richard P. Bentall (a1), Fred J. Nye (a1) and Richard H. T. Edwards (a1)
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