Skip to main content Accessibility help
×
Home

Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department

  • Mary Cannon (a1), Elizabeth Walsh (a1), Christopher Hollis (a2), Maresc Kargin (a1), Eric Taylor (a3), Robin M. Murray (a1) and Peter B. Jones (a4)...

Abstract

Background

Schizophrenia has been linked with psychological problems in childhood but there is little information on precursors of affective psychosis.

Aims

To compare childhood psychological antecedents of adult schizophrenia and affective psychosis.

Method

Childhood item sheets, which give standardised information on signs and symptoms of mental illness in the year preceding assessment are completed for all attendees at the children's department of the Maudsley and Bethlem Royal Hospital. We examined item sheet data on individuals with an adult diagnosis of schizophrenia (n=59) or affective psychosis (n=27) and a comparison group with no adult mental illness (n=86) (all had attended the department).

Results

Abnormal suspiciousness or sensitivity and relationship difficulties with peers are associated with later schizophrenia. In contrast, affective psychosis is associated with childhood hysterical symptoms and disturbances in eating.

Conclusions

Childhood psychological precursors for schizophrenia and affective psychosis differ and do not simply reflect non-specific psychiatric disturbance in adolescence.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department
      Available formats
      ×

Copyright

Corresponding author

Dr Mary Cannon, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK. e-mail: m.cannon@iop.kcl.ac.uk

Footnotes

Hide All

See editorial, pp. 395–396, this issue.

Declaration of interest

None. Funding detailed in Acknowledgements.

Footnotes

References

Hide All
Ambelas, A. (1992) Preschizophrenics: adding to the evidence, sharpening the focus. British Journal of Psychiatry, 160, 401404.
Brown, J. & Dodge, K. A. (1997) Early peer relations and child psychiatry. In Handbook of Child and Adolescent Psychiatry, vol. 1 (eds Greenspan, S., Weider, S. & Osofksy, J.), pp. 304319. New York: John Wiley & Sons.
Cannon, M., Jones, P., Gilvarry, C., et al (1997) Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. American Journal of Psychiatry, 154, 15441550.
Caspi, A., Moffitt, T. E., Newman, D. L., et al (1996) Behavioural observations at age 3 years predict adult psychiatric disorders. Archives of General Psychiatry, 53, 10331039.
Crow, T. J., Done, D. J. & Sacker, A. (1995) Childhood precursors of psychosis as clues to its evolutionary origin. European Archives of Psychiatry and Clinical Neuroscience, 245, 6169.
Davidson, M., Reichenberg, A., Rabinowitz, J., et al (1999) Behavioural and intellectual markers for schizophrenia in apparently healthy males. American Journal of Psychiatry, 156, 13281335.
Done, D. J., Crow, T. J., Johnstone, E. C., et al (1994) Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11. British Medical Journal, 309, 699703.
Garmezy, N. (1974) Child at risk: the search for the antecedents of schizophrenia. Schizophrenia Bulletin, 8, 1390.
Goldthorpe, J. H. & Hope, K. (1974) The Social Grading of Occupations – A New Approach and Scale. Oxford: Clarendon Press.
Goodman, R. & Simonoff, E. (1991) Reliability of clinical ratings by trainee child psychiatrists: a research note. Journal of Child Psychology and Psychiatry, 32, 551555.
Guth, C., Jones, P. & Murray, R. (1993) Familial psychiatric illness and obstetric complications in early-onset affective disorder. A case-control study. British Journal of Psychiatry, 163, 492498.
Hartman, E., Milofsky, E. & Vaillant, G. (1984) Vulnerability to schizophrenia: prediction of adult schizophrenia using childhood information. Archives of General Psychiatry, 41, 10501056.
Hollis, C. (1995) Child and adolescent (juvenile onset) schizophrenia. A case control study of premorbid developmental impairments. British Journal of Psychiatry, 166, 489495.
Hollis, C. & Taylor, E. (1997) Schizophrenia: a critique from the developmental psychopathology perspective. In Neurodevelopment and Adult Psychopathology, pp. 213233. Cambridge: Cambridge University Press.
Jones, P. B., Rodgers, B., Murray, R. M., et al (1994) Child developmental risk factors for adult schizophrenia in the 1946 British birth cohort. Lancet, 344, 13981402.
Malmberg, A., Lewis, G., David, A., et al (1998) Premorbid adjustment and personality in people with schizophrenia. British Journal of Psychiatry, 172, 308313.
McGuffin, P., Farmer, A. & Harvey, I. (1991) A polydiagnostic application of operational criteria in studies of psychotic illness: development and reliability of the OPCRIT system. Archives of General Psychiatry, 48, 764770.
Offord, D. R. & Cross, L. A. (1969) Behavioural antecedents of adult schizophrenia. Archives of General Psychiatry, 21, 267283.
Pritchard, M. & Graham, P. (1966) An investigation of a group of patients who have attended both the child and adult departments of the same psychiatric hospital. British Journal of Psychiatry, 112, 603612.
Rutter, M. (1984) Psychopathology and development. I: Childhood antecedents of adult psychiatric disorder. Australian and New Zealand Journal of Psychiatry, 18, 225234.
Sham, P. (1995) Genetic epidemiology. British Medical Bulletin, 52, 408433.
Sigurdsson, E., Fombonne, E., Sayal, K., et al (1999) Neurodevelopmental antecedents of early-onset bipolar affective disorder. British Journal of Psychiatry, 174, 121127.
Stata Corporation (1995) Stata Statistical Software Release 5.0. College Station, TX: Stata Corporation.
Thorley, G. (1982) The Bethlem Royal and Maudsley hospitals' clinical data register for children and adolescents. Journal of Adolescence, 5, 179189.
Thorley, G. (1987) Factor study of a psychiatric clinic child rating scale. Based on ratings made by clinicians on child and adolescent clinic attenders. British Journal of Psychiatry, 150, 4959.
Wagner, P. S. (1996) First person account: a voice from another closet. Schizophrenia Bulletin, 22, 399401.
World Health Organization (1992) Tenth Revision of the International Classification of Diseases and Related Health Problems (ICD–10). Geneva: WHO.
Zeitlin, H. (1986) The Natural History of Psychiatric Disorder in Children. Oxford: Oxford University Press.

Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department

  • Mary Cannon (a1), Elizabeth Walsh (a1), Christopher Hollis (a2), Maresc Kargin (a1), Eric Taylor (a3), Robin M. Murray (a1) and Peter B. Jones (a4)...

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department

  • Mary Cannon (a1), Elizabeth Walsh (a1), Christopher Hollis (a2), Maresc Kargin (a1), Eric Taylor (a3), Robin M. Murray (a1) and Peter B. Jones (a4)...
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *