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Psychiatric presentation of voltage-gated potassium channel antibody-associated encephalopathy: Case report

  • U. D. Parthasarathi (a1), T. Harrower (a2), M. Tempest (a3), J. R. Hodges (a4), C. Walsh (a3), P. J. McKenna (a3) and P. C. Fletcher (a5)...
Summary

Voltage-gated potassium channel antibody encephalopathy, a rare cause of limbic encephalopathy, typically presents with memory impairment and seizures. Psychiatric symptoms have not been emphasised in the literature. Here we describe a 58-year-old man who presented with panic attacks and psychogenic non-epileptic seizures and, later on, developed delusions and hallucinations and then confusion. He was found to have antibodies to voltage-gated potassium channels. Treatment with immuno-modulatory therapy resulted in almost complete recovery.

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Copyright
Corresponding author
U. D. Parthasarathi, Box 175, Liaison Psychiatry Service, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK. Tel: 01223 216167; fax: 01223 274363; email: upartha@hotmail.co.uk
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Declaration of interest

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References
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Psychiatric presentation of voltage-gated potassium channel antibody-associated encephalopathy: Case report

  • U. D. Parthasarathi (a1), T. Harrower (a2), M. Tempest (a3), J. R. Hodges (a4), C. Walsh (a3), P. J. McKenna (a3) and P. C. Fletcher (a5)...
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