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Psychophysiological and behavioural characteristics of individuals comorbid for antisocial personality disorder and schizophrenia-spectrum personality disorder

  • Robert A. Schug (a1), Adrian Raine (a1) and Rand R. Wilcox (a1)
Abstract
Background

Few studies have examined people with comorbid schizophrenia-spectrum personality disorder and antisocial personality disorder, a subgroup who may differ psychophysiologically and behaviourally from those with either condition alone.

Aims

To test whether individuals with both types of personality disorder are particularly characterised by reduced orienting and arousal and by increased criminal offending.

Method

In a community adult sample, self-reported crime and skin conductance orienting were collected on four diagnostic groups: schizophrenia-spectrum personality disorder only; antisocial personality disorder only; comorbidity of the two disorders; and a control group.

Results

The comorbid group showed significantly higher levels of criminal behaviour than the other three groups. They also showed reduced skin conductance orienting to neutral tones compared with the other groups, and significantly reduced arousal and orienting to significant stimuli compared with the control group.

Conclusions

Reduced orienting may reflect a neurocognitive attentional risk factor for both antisocial and schizotypal personality disorders that indirectly reflects a common neural substrate to these disorders.

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Copyright
Corresponding author
Robert Schug, Department of Psychology, University of Southern California, Seeley G. Mudd Building, Room 501, Los Angeles, CA 90089-1061, USA. Tel: + 1213 821 5211; email: schug@usc.edu
Footnotes
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Declaration of interest

None.

Funding detailed in Acknowledgements.

Footnotes
References
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Bilder, R. M. (2006) Schizophrenia. In Clinical Neuropsychology: A Pocket Handbook for Assessment (2nd edn) (eds. Snyder, P. J., Nussbaum, P. D. & Robins, D. L.) pp. 398414. American Psychological Association.
Brower, M. C. & Price, B. H. (2001) Neuropsychiatry of frontal lobe dysfunction in violent and criminal behaviour: a critical review. Journal of Neurology, Neurosurgery and Psychiatry, 71, 720726.
Critchley, H. D. (2002) Electrodermal responses: what happens in the brain. Neuroscientist, 8, 132142.
Critchley, H. D., Elliott, R., Mathias, C. J., et al (2000) Neural activity relating to the generation and representation of galvanic skin conductance response: a functional magnetic imaging study. Journal of Neuroscience, 20, 30333040.
Davison, A. C., & Hinkley, D. V. (1997) Bootstrap Methods and Their Application. Cambridge University Press.
Dawson, M. E., Nuechterlein, K. H., Schell, A. M., et al (1994) Autonomic abnormalities in schizophrenia: state or trait indicators? Archives of General Psychiatry, 51, 813824.
Efron, B. & Tibshirani, R. J. (1993) An Introduction to the Bootstrap. Chapman & Hall.
Elliott, D. S., Ageton, S., Huizinga, D. et al (1983) The Prevalence and Incidence of Delinquent Behavior: 1976–1980. National Youth Survey, Report 26. Behavior Research Institute.
First, M. B., Gibbon, M., Spitzer, R. L., et al (1997a) User's Guide for the Structured Clinical Interview for DSM–IV Axis II Personality Disorders (SCID–II). American Psychiatric Press.
First, M. B., Spitzer, R. L., Gibbon, M., et al (1997b) User's Guide for the Structured Clinical Interview for DSM–IV Axis I Disorders – Clinician Version (SCID–CV). American Psychiatric Press.
Fowles, D. C. (1993) Electrodermal activity and antisocial behavior: empirical findings and theoretical issues. In Progress in Electrodermal Research (eds Roy, C., Bouscein, W., Fowles, D. C. et al), pp. 223237. Plenum.
Hirose, S. (2001) Effective treatment of aggression and impulsivity in antisocial personality disorder with risperidone. Psychiatry and Clinical Neurosciences, 55, 161162.
Hollingshead, A. B. (1975) Four Factor Index of Social Status. Department of Sociology, Yale University.
Lapierre, D., Braun, C. M. J. & Hodgins, S. (1995) Ventral frontal deficits in psychopathy: neuropsychological test findings. Neuropsychologic, 33, 139151.
Lorber, M. F. (2004) Psychophysiology of aggression, psychopathy, and conduct problems: a meta-analysis. Psychological Bulletin, 130, 531552.
Lösel, F. (2001) Is effective treatment of psychopathy possible? What we know and what we need to know. In Violence and Psychopathy (eds Raine, A. & Sanmartín, J.), pp. 171195. Kluwer/Plenum.
Moran, P. & Hodgins, S. (2004) The correlates of comorbid antisocial personality disorder in schizophrenia. Schizophrenia Bulletin, 30, 791802.
Morgan, A. B. & Lilienfeld, S. O. (2000) A meta-analytic review of the relation between antisocial behavior and neuropsychological measures of executive function. Clinical Psychology Review, 20, 113136.
Öhman, A. (1981) Electrodermal activity and vulnerability to schizophrenia: a review. Biological Psychology, 12, 87145.
Raine, A. (1997) Antisocial behavior and psychophysiology: a biosocial perspective and a prefrontal dysfunction hypothesis. In Handbook of Antisocial Behavior (eds Stoff, D. M., Breiling, J. & Maser, J. D.), pp. 289304. Wiley.
Raine, A. (2006a) Pursuing a second generation of research on crime and schizophrenia. In Crime and Schizophrenia: Causes and Cures. (ed. Raine, A.), pp. 311, Nova.
Raine, A. (2006b) Schizotypal personality: neurodevelopmental and psychosocial trajectories. Annual Review of Clinical Psychology, 2, 291326.
Raine, A. & Venables, P. H. (1984) Electrodermal nonresponding, antisocial behavior, and schizoid tendencies in adolescents. Psychophysiology, 21, 424433.
Raine, A., Bihrle, S., Venables, P. H., et al (1999) Skin conductance orienting deficits and increased alcoholism in schizotypal criminals. Journal of Abnormal Psychology, 108, 299306.
Raine, A., Lencz, T., Bihrle, S., et al (2000) Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Archives of General Psychiatry, 57, 119127.
Raine, A., Lencz, T., Yaralian, P., et al (2002a) Prefrontal structural and functional deficits in schizotypal personality disorder. Schizophrenia Bulletin, 28, 501513.
Raine, A., Venables, P. H., Mednick, S., et al (2002b) Increased psychophysiological arousal and orienting at ages 3 and 11 years in persistently schizotypal adults. Schizophrenia Research, 54, 7785.
Scerbo, A. S., Freedman, L. W., Raine, A., et al (1992) A major effect of recording site on measurement of electrodermal activity. Psychophysiology, 29, 241246.
Seigel, L. J. (2006) Criminology (9th edn). Wadsworth.
Thiel, C. M., Zilles, K. & Fink, G. R. (2004) Cerebral correlates of alerting, orienting, and reorienting of visuospatial attention: an event-related fMRI study. NeuroImage, 21, 318328.
Venables, P. H. & Christie, M. J. (1980) Electrodermal activity. In Techniques in Psychophysiology (eds Martin, I. & Venables, P. H.). pp. 267. Wiley.
Ventura, J., Liberman, R. P., Green, M. F., et al (1998) Training and quality assurance with the Structured Clinical Interview for DSM–IV (SCID–I/P). Psychiatry Research, 79, 163173.
Walker, C., Thomas, J. & Allen, T. S. (2003) Treating impulsivity, irritability, and aggress on of antisocial personality disorder with quetiapine. International Journal of Offender Therapy and Comparative Criminology, 47, 556567.
Wilcox, R. R. (2003) Applying Contemporary Statistical Techniques. Academic Press.
Wilcox, R. R. (2005) New methods for comparing groups: strategies for increasing the probability of detecting true differences. Current Directions in Psychological Science, 14, 272275.
Williams, L. M., Brammer, M. J., Skerrett, D., et al (2000) The neural correlates of orienting: an integration of fMRI and skin conductance orienting response. Brain Imaging, 11, 30113015.
Yechiam, E., Kanz, J. E., Bechara, A., et al (2007) Neurocognitive deficits related to poor decision-making in people behind bars: a peek inside their brain. Psychonomic Bulletin and Review, in press.
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Psychophysiological and behavioural characteristics of individuals comorbid for antisocial personality disorder and schizophrenia-spectrum personality disorder

  • Robert A. Schug (a1), Adrian Raine (a1) and Rand R. Wilcox (a1)
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