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Relationship between subjective and objective cognitive function in the early and late prodrome

  • Frauke Schultze-Lutter (a1), Stephan Ruhrmann (a1), Heinz Picker (a1), Heinrich Graf Von Reventlow (a1), Bianca Daumann (a1), Anke Brockhaus-Dumke (a1), Joachim Klosterkötter (a1) and Ralf Pukrop (a2)...

Abstract

Background

Cognitive disturbances have been demonstrated in individuals with potentially prodromal symptoms in objective–neuropsychological as well as subjective-symptomatic studies. Yet, the relation between subjective and objective deficits and to different prodromal states is unclear

Aims

To explore interactions between subjective and objective cognitive measures in different prodromal states

Method

In participants with an early (n=33) or late (n=69) initial prodromal state, cognitive subjective and objective deficits were assessed with the Schizophrenia Proneness Instrument and a comprehensive neuropsychological test battery

Results

Participants with an early initial prodromal state were less impaired than those with a late initial state. Subjective and objective cognitive deficits were unrelated, excepttime-limited neurocognitive speed measures and subjectively reduced stress tolerance, especially in participants with an early initial prodromal state

Conclusions

Subjective and objective cognitive deficits are generally unrelated in the psychosis prodrome and as such they can add complementary information valuable for prediction. However, possible associations between the two levels might be better detectable in the less impaired early initial prodromal state

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Copyright

Corresponding author

Dr Frauke Schultze-Lutter, University of Cologne, Department of Psychiatry and Psychotherapy, Early Recognition and Intervention Centre for Mental Crises (FETZ), 50924 Cologne, Germany, Tel: +49 221 478 6098; fax: +49 221 478 3624; email: frauke.schultze-lutter@uk-koeln.de

Footnotes

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Declaration of interest

None.

Funding detailed in Acknowledgements.

Footnotes

References

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Relationship between subjective and objective cognitive function in the early and late prodrome

  • Frauke Schultze-Lutter (a1), Stephan Ruhrmann (a1), Heinz Picker (a1), Heinrich Graf Von Reventlow (a1), Bianca Daumann (a1), Anke Brockhaus-Dumke (a1), Joachim Klosterkötter (a1) and Ralf Pukrop (a2)...

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Relationship between subjective and objective cognitive function in the early and late prodrome

  • Frauke Schultze-Lutter (a1), Stephan Ruhrmann (a1), Heinz Picker (a1), Heinrich Graf Von Reventlow (a1), Bianca Daumann (a1), Anke Brockhaus-Dumke (a1), Joachim Klosterkötter (a1) and Ralf Pukrop (a2)...
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