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Solving a weighty problem: Systematic review and meta-analysis of nutrition interventions in severe mental illness

  • Scott B. Teasdale (a1), Philip B. Ward (a2), Simon Rosenbaum (a3), Katherine Samaras (a4) and Brendon Stubbs (a5)...
Abstract
Background

Nutrition interventions would appear fundamental for weight management and cardiometabolic risk reduction in people experiencing severe mental illness (SMI). Comprehensive evaluation of nutrition interventions is lacking.

Aims

To subject randomised controlled trials of nutrition interventions in people with SMI to systematic review and meta-analysis, and to measure anthropometric and biochemical parameters and nutritional intake.

Method

An electronic database search identified trials with nutrition intervention components. Trials were pooled for meta-analysis. Meta-regression analyses were performed on anthropometric moderators.

Results

Interventions led to significant weight loss (19 studies), reduced body mass index (17 studies), decreased waist circumference (10 studies) and lower blood glucose levels (5 studies). Dietitian-led interventions (6 studies) and studies delivered at antipsychotic initiation (4 studies) had larger effect sizes.

Conclusions

Evidence supports nutrition interventions as standard care in preventing and treating weight gain among people experiencing SMI.

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Copyright
Corresponding author
Scott Teasdale, Bondi Community Centre, 26 Llandaff St, Bondi Junction, NSW 2022, Australia. Email: Scott.Teasdale@sesiahs.health.nsw.gov.au
Footnotes
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See editorial, pp. 94–95, this issue.

Declaration of interest

None.

Footnotes
References
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Solving a weighty problem: Systematic review and meta-analysis of nutrition interventions in severe mental illness

  • Scott B. Teasdale (a1), Philip B. Ward (a2), Simon Rosenbaum (a3), Katherine Samaras (a4) and Brendon Stubbs (a5)...
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