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A Study of Pairs of Sibs both Hospitalized for Mental Disorder

Published online by Cambridge University Press:  29 January 2018

Ming-Tso Tsuang
Ming-Tso Tsuang*
Affiliation:
M.R.C. Psychiatric Genetics Research Unit, Institute of Psychiatry, Maudsley Hospital, London, S.E.5; Department of Neurology and Psychiatry, National Taiwan University Hospital, Taipei, Taiwan, Republic of China (Formosa)
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Extract

The present study is concerned with what is inherited in mental disorder. Is it an unspecific tendency to mental disorder, is it specific symptoms or features such as age of onset, course or outcome, or is it psychiatric diagnosis?

The study of pairs of relatives with mental disorder is certainly the best approach to investigating the problem of what is inherited. Unfortunately there has been a paucity of studies primarily dealing with this particular problem.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 496 , March 1967 , pp. 283 - 300
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Ambroumova, A. G. (1957). “Au sujet des dites schizophrénics familiales.” Zh. Nevropat. Psikhiat., 57, 1101–1105.Google Scholar
Astrup, C. (1962). Schizophrenia: Conditional Reflex Studies. Springfield, Ill., Thomas.Google Scholar
Bleuler, M. (1941). Krankheitsverlauf, Persönlichkeit und Verwandischaft Schizophrener und ihre gegenseitigen Beziehungen. Leipzig, Thieme. (Original not available. Abstract by Dr. Eliot Slater consulted.)Google Scholar
Eysenck, H. J. (1960). “Classification and the problems of diagnosis.” In: Handbook of Abnormal Psychology (ed. Eysenck, H. J.). London: Pitman Medical Publishing Go.Google Scholar
Fish, F. J. (1958) “A clinical investigation of chronic schizophrenia.” J. ment. Sci., 104, 34–54.Google Scholar
Kallmann, F. J. (1946). “The genetic theory of schizophrenia.” Amer. J. Psychiat., 103, 309–322.Google Scholar
Kallmann, F. J. (1950). “The genetics of psychoses: an analysis of 1,232 twin index families.” In: Congr. Internal. Psychiat., Rapports, 6, 1–27. Paris, Hermann.Google Scholar
Kant, O. (1942). “The incidence of psychoses and other mental abnormalities in the families of recovered and deteriorated schizophrenic patients.” Psychiat. Quart., 16, 176–186.Google Scholar
Kay, D. W. K., and Roth, M. (1961). “Environmental and hereditary factors in the schizophrenias of old age (‘late paraphrenia’) and their bearing on the general problem of causation in schizophrenia.” J. ment. Sci., 107, 649–686.CrossRefGoogle ScholarPubMed
Kraulis, W. (1939). “Zur Klinik der Erbpsychosen.” Allg. Z. Psychiat., 113, 32–62.Google Scholar
Langfeldt, G. (1956). “The prognosis in schizophrenia.” Acta psychiat. scand., Suppl., 110.Google Scholar
Leonhard, K. (1957). Die Aufteilung der endogenen Psychosen. Berlin: Akademie Verlag.Google Scholar
Luxenburger, H. (1935). “Untersuchungen an schizophrenen Zwillingen und ihren Geschwistern zur Prüfung der Realität von Manifestationsschwankungen.” Z. ges. Neurol. Psychiat., 154, 351–394.Google Scholar
Mitsuda, H. (1957). “Klinische-erbbiologische Untersuchung der endogenen Psychosen.” Acta genet. (Basel), 7, 371–377.Google Scholar
Mott, F. W. (1910). “The Huxley lecture on hereditary aspects of nervous and mental disease.” Brit. med. J., ii, 1013–1020.CrossRefGoogle Scholar
Myerson, A. (1925). The Inheritance of Mental Disease. Baltimore: Williams and Wilkins.Google Scholar
Ødegaard, Ø. (1963). “The psychiatric disease entities in the light of a genetic investigation.” Acta psychiat. scand., Suppl., 169, 94–104.Google Scholar
Penrose, L. S. (1942). “Auxiliary genes for determining sex as contributory causes of mental illness.” J. ment. Sci., 88, 308–316 CrossRefGoogle Scholar
Penrose, L. S. (1945). “Survey of cases of familial mental illness.” Div. Psychiat. Res. Ont. Dept. Health, Mimeographed typescript.Google Scholar
Penrose, L. S. (1950). “Research methods in human genetics.” In: Congr. Internal. Psychiat., Rapports, 6, 41–54. Paris: Hermann.Google Scholar
Rosenthal, D. (1961). “Sex distribution and the severity of illness among samples of schizophrenic twins.” J. psychiat. Res., 1, 26–36.CrossRefGoogle ScholarPubMed
Penrose, L. S. (1962). “Familial concordance by sex with respect to schizophrenia.” Psychol. Bull., 59, 401–421.Google Scholar
Roth, M. (1960). “Ageing and the mental diseases of the aged.” In: Clinical Psychiatry by Mayer-Gross, W., Slater, E., and Roth, M., 2nd ed. London: Cassell.Google Scholar
Schulz, B. (1932). “Zur Erbpathologie der Schizophrenic” Z. ges. Neurol. Psychiat., 143, 175–293.CrossRefGoogle Scholar
Slater, E. (1944). “Genetics in psychiatry.” J. ment. Sci., 90, 17–35. (Recent Progress in Psychiatry. Vol. I.)Google Scholar
Penrose, L. S. (1947). “Genetical causes of schizophrenic symptoms.” Mschr. Psychiat. Neurol., 113, 50–58.Google Scholar
Penrose, L. S. (1950). “Psychiatric genetics.” In: Recent Progress in Psychiatry. Vol. II. (ed. Fleming, G. W. T. H.). London: Churchill.Google Scholar
Penrose, L. S. (1953). “Sex-linked recessives in mental illness?” Acta genet. (Basel), 4, 273–280.Google Scholar
Penrose, L. S. with the assistance of Shields, J. (1953). Psychotic and Neurotic Illnesses in Twins. Med. Res. Coun. Spec. Rep. Ser. No. 278. London: H.M.S.O.Google Scholar
Slater, E., (1958). “The monogenic theory of schizophrenia.” Acta genet. (Basel), 8, 50–56.Google Scholar
Strömgren, E. (1935). “Zum Ersatz des Weinbergschen ‘abgekürzten Verfahrens’; zugleich ein Beitrag zur Frage von der Erblichkeit des Erkrankungsalters bei der Schizophrenic” Z. ges. Neurol. Psychiat., 153, 784–797.Google Scholar
Tsuang, M. T. (1965). “A study of pairs of sibs both hospitalized for mental disorder.” Ph.D. Thesis, University of London.Google Scholar
Vaillant, G. E. (1963). “Manic-depressive heredity and remission in schizophrenia.” Brit. J. Psychiat., 109, 746–749.Google Scholar
Zehnder, M. (1940). “Über Krankheitsbild und Krankheitsverlauf bei schizophrenen Geschwistern.” Mschr. Psychiat. Neurol., 103, 230–277.Google Scholar
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