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Using generic preference-based measures in mental health: psychometric validity of the EQ-5D and SF-6D

  • Brendan Mulhern, Clara Mukuria, Michael Barkham, Martin Knapp, Sarah Byford, Dj⊘ra Soeteman and John Brazier...
Abstract
Background

Generic preference-based measures (EuroQoL-5D (EQ-5D) and SF-6D) are used in the economic evaluation of mental health interventions. However, there are inconsistent findings regarding their psychometric properties.

Aims

To investigate the psychometric properties of the EQ-5D and SF-6D in different mental health conditions, using seven existing data-sets.

Method

The construct validity and responsiveness of the measures were assessed in comparison with condition-specific indicators.

Results

Evidence for construct validity and responsiveness in common mental health and personality disorders was found (correlations 0.22–0.64; effect sizes 0.37–1.24; standardised response means 0.45–1.31). There was some evidence for validity in schizophrenia (correlations 0.05–0.43), but responsiveness was unclear.

Conclusions

EQ-5D and SF-6D can be used in the economic evaluation of interventions for common mental health problems with some confidence. In schizophrenia, a preference-based measure focused on the impact of mental health should be considered.

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Copyright
Corresponding author
Brendan Mulhern, Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Regent Court, Sheffield S1 4DA, UK. Email: b.mulhern@sheffield.ac.uk
Footnotes
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Declaration of interest

J.B. developed the SF-6D. M.B. was part of the CORE-OM development group.

Footnotes
References
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Using generic preference-based measures in mental health: psychometric validity of the EQ-5D and SF-6D

  • Brendan Mulhern, Clara Mukuria, Michael Barkham, Martin Knapp, Sarah Byford, Dj⊘ra Soeteman and John Brazier...
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