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Improving adherence to NICE guidance for bipolar illness: valproate use in women of childbearing potential

  • Shubhra Mace (a1) and David Taylor (a1)
Abstract
Aims and method

To assess the impact in the South London and Maudsley NHS Foundation Trust of a 20-month quality improvement programme on adherence with National Institute for Health and Clinical Excellence (NICE) recommendations for the use of valproate for bipolar illness in women of childbearing potential.

Results

Significant improvement was noted between baseline and final audit in rates of information provision (10% v. 63%, P < 0.0001), contraceptive use (15% v. 38%, P = 0.0003) and folate prescription (3% v. 35%, P < 0.0001).

Clinical implications

Adherence to guidance can be usefully improved by a sustained intervention programme.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
Shubhra Mace (shubhra.mace@slam.nhs.uk)
Footnotes
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Declaration of interest

D.T. has received consultancies fees, lecturing honoraria and/or research funding from Astra Zeneca, Janssen-Cilag, Servier, Sanofi-aventis, Lundbeck, Bristol-Myers Squibb, Novartis, Eli Lilly and Wyeth.

Footnotes
References
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Improving adherence to NICE guidance for bipolar illness: valproate use in women of childbearing potential

  • Shubhra Mace (a1) and David Taylor (a1)
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