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Infant zygosity can be assigned by parental report questionnaire data

  • Thomas S Price (a1), Bernard Freeman (a2), Ian Craig (a3), Stephen A Petrill (a4), Lorna Ebersole (a5) and Robert Plomin (a6)...
Abstract

A parental report questionnaire posted to a population sample of 18-month-old twins correctly assigned zygosity in 95%of cases when validated against zygosity determined by identity of polymorphic DNA markers. The questionnaire was as accurate when readministered at 3 years of age, with 96% of children being assigned the same zygosity on both occasions. The results validate the use of parental report questionnaire data to determine zygosity in infancy. Twin Research (2000) 3, 129–133.

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*Correspondence: Thomas S Price, Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, SE5 8AF, UK. Tel: + 44 (0) 207 848 0961; Fax: + 44 (0) 207 848 0866
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Twin Research and Human Genetics
  • ISSN: 1832-4274
  • EISSN: 1839-2628
  • URL: /core/journals/twin-research-and-human-genetics
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