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    Orsini, Caitlin A. Moorman, David E. Young, Jared W. Setlow, Barry and Floresco, Stan B. 2015. Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models. Neuroscience & Biobehavioral Reviews, Vol. 58, p. 147.


Linking neural activity to complex decisions

  • DOI:
  • Published online: 16 September 2013

In the 1990s, seminal work from Newsome and colleagues made it possible to study the neuronal mechanisms of simple perceptual decisions. The key strength of this work was the clear and direct link between neuronal activity and choice processes. Since then, a great deal of research has extended these initial discoveries to more complex forms of decision making, with the goal of bringing the same strength of linkage between neural and psychological processes. Here, we discuss the progress of two such research programs, namely our own, that are aimed at understanding memory-guided decisions and reward-guided decisions. These problems differ in the relevant brain areas, in the progress that has been achieved, and in the extent of broader understanding achieved so far. However, they are unified by the use of theoretical insights about how to link neuronal activity to decisions.

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*Address correspondence to: Dr. Benjamin Hayden, University of Rochester, Brain and Cognitive Sciences, Center for Visual Science, University of Rochester, Rochester, NY 14621. E-mail:
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Visual Neuroscience
  • ISSN: 0952-5238
  • EISSN: 1469-8714
  • URL: /core/journals/visual-neuroscience
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