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Spectral sensitivity of ON and OFF responses from the optic nerve of goldfish

  • Paul J. DeMarco (a1) and Maureen K. Powers (a1)
  • DOI:
  • Published online: 01 June 2009

The vertebrate retina processes visual information in parallel neural pathways known as the ON and OFF pathways. These pathways encode increments and decrements of light independently as excitatory responses. We examined the photopic spectral response of ON and OFF mechanisms in goldfish by measuring the sensitivity of optic nerve responses to the onset and termination of stimuli of various wavelengths. Using various adapting backgrounds, we found that the ON and OFF responses have different spectral sensitivities. The weighting of the cone inputs to the responses was estimated by an algebraic summation model. This model suggests that for the ON response, input from S-cones is stronger and more independent than for the OFF response, and M- and L-cones show stronger antagonism in the ON response than in the OFF response. The OFF response probably receives input from all cone types, but spectral antagonism is weak and its dominant input is from L-cones.

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E.D. Adrian & R. Matthews (1927). The action of light on the eye. Journal of Physiology 63, 378414.

H.B. Barlow , R. Fitzhugh & S.W. Kuffler (1957). Change in organization in the receptive fields of the cat's retina during dark-adaptation. Journal of Physiology 137, 338354.

C.J. Bassi , R.C. Williams & M.K. Powers (1984). Light transmittance by goldfish eyes of different sizes. Vision Research 24, 14151419.

R.D. Beauchamp & J.S. Rowe (1977). Goldfish spectral sensitivity: a conditioned heart rate measure in restrained or curarized fish. Vision Research 17, 617624.

R.D. Beauchamp , J.S. Rowe & L.A. O'Reilly (1979). Goldfish spectral sensitivity: identification of the three cone mechanisms in heart-rate conditioned fish using colored adapting backgrounds. Vision Research 19, 12951302.

R.W. Bowen , J. Pokorny & V.C. Smith (1989). Sawtooth contrast sensitivity: decrements have the edge. Vision Research 29, 15011509.

R.M. Boynton , M. Ikeda & W.S. Stiles (1964). Interactions among chromatic mechanisms as inferred from positive and negative increments thresholds. Vision Research, 4, 87177.

T.E. Cohn & D.J. Lesley (1975). Spatial summation of foveal increments and decrements. Vision Research, 15, 389399.

N.W. Daw (1967). Goldfish retina: organization for simultaneous color contrast. Science 158, 942944.

F.M. De Monasterio (1979). Asymmetry of on- and off-pathways of blue sensitive cones of the retina of macaques. Brain Research 166, 3948.

S.S. Easter , P.R. Johns & L.R. Baumann (1977). Growth of adult goldfish eye, 1: Optics. Vision Research, 17, 469477.

H.U. Evers & P. Gouras (1986). Three cone mechanisms in the primate retina: two with, one without OFF-center bipolar responses. Vision Research, 26, 245254.

M. Falzett , J.D. Nussdorf & M.K. Powers (1988). Responsivity and absolute sensitivity of retinal ganglion cells in goldfish of different sizes, when measured under “psychophysical” conditions. Vision Research 28, 223237.

E.V. Famiglietti , A. Kaneko & M. Tachibana (1977). Neuronal architecture of ON and OFF pathways to ganglion cells in carp retina. Science 198, 12671269.

F.I. Hárosi (1976). Spectral relations of cone pigments in goldfish. Journal of General Physiology 68, 6580.

Y. Hashimoto , M. Abe & M. Inokuchi (1980). Identification of interplexiform cell in dace retina by dye-injection method. Brain Research 197, 331340.

C.W. Hawryshyn & R. Beauchamp (1985). Ultraviolet photosensitivity in goldfish: an independent U.V. retinal mechanism. Vision Research, 25, 1120.

R.M. Herrick (1956). Foveal luminance discrimination as a function of the decrement or increment in luminance. Journal of Comparative Physiology and Psychology 49, 437443.

D.H. Hubel & T.N. Wiesel (1960). Receptive fields of optic nerve fibers in the spider monkey. Journal of Physiology 154, 572580.

J. Krauskopf (1980). Discrimination and detection of changes in luminance. Vision Research 20, 671677.

R. Kretz , G. Rager & T.T. Norton (1986). Laminar organization of on and off regions and ocular dominance in the striate cortex of the tree shrew (Tupaia belangeri). Journal of Comparative Neurology 251, 135145.

S. LeVay , S.K. McConnell & M.B. Luskin (1987). Functional organization of primary visual cortex in the mink (Mustela vison), and a comparison with the cat. Journal of Comparative Neurology 257, 422441.

R.M. Mackintosh , J. Bilotta & I. Abramov (1987). Contributions of short-wavelength cones to goldfish retinal ganglion cells. Journal of Comparative Physiology A 161, 8594.

J.G. Malpeli , & P.H. Schiller (1978). Lack of blue off-center cells in the visual system of the monkey. Brain Research 141, 385389.

W.B. Marks (1965). Visual pigments of single goldfish cones. Journal of Physiology 178, 1432.

C. Neumeyer (1984). On spectral sensitivity of the goldfish: evidence for neural interactions between different “cone mechanisms”. Vision Research, 24, 12231231.

C. Neumeyer , & K. Arnold (1989). Tetrachromatic color vision in the goldfish becomes trichromatic under white adaptation light of moderate intensity. Vision Research, 29, 17191727.

B.T. Olsen , T. Schneider , & E. Zrenner (1986). Characteristics of rod driven off-responses in cat ganglion cells. Vision Research, 26, 835845.

A.S. Patel , & R.W. Jones (1968). Increment and decrement visual thresholds. Journal of the Optical Society of America 58, 696699.

M.K. Powers (1978). Light-adapted spectral sensitivity of the goldfish: a reflex measure. Vision Research, 18, 11311136.

C. Rashbass (1970). The visibility of transient changes in luminance. Journal of Physiology 210, 165186.

J.A.J. Roufs (1974). Dynamic properties of vision–IV: Thresholds of decremental flashes, incremental flashes, and doublets in relation to flicker fusion. Vision Research, 14, 831852.

P.H. Schiller (1984). The connections of the retinal on and off pathways to the lateral geniculate nucleus of the monkey. Vision Research, 24, 923932.

J.M. Shefner , & M.W. Levine (1976). A psychophysical demonstration of goldfish trichromacy. Vision Research, 16, 671673.

A.D. Short (1966). Decremental and incremental thresholds. Journal of Physiology 185, 646654.

H.G. Wagner , E.F. MacNichol , & M.L. Wolbrasht (1960). The response properties of single ganglion cells in the goldfish retina. Journal of General Physiology 43, 4562.

T.G. Wheeler (1979). Retinal on and off responses convey different chromatic information to the CNS. Brain Research 160, 145149.

P. Witkovsky (1965). The spectral sensitivity of retinal ganglion cells in the carp. Vision Research, 5, 603614.

D. Yager (1967). Behavioral measures and theoretical analysis of spectral sensitivity and spectral saturation in the goldfish(Carassius auratus). Vision Research 7, 707727.

D. Yager (1969). Behavioral measures of spectral sensitivity in the goldfish following chromatic adaption. Vision Research, 9, 179186.

E. Zrenner , & P. Gouras (1981). Characteristics of the blue-sensitive cone mechanism in primate retinal ganglion cells. Vision Research, 21, 16051609.

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Visual Neuroscience
  • ISSN: 0952-5238
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