Hostname: page-component-7dd5485656-hw7sx Total loading time: 0 Render date: 2025-10-30T16:31:08.070Z Has data issue: false hasContentIssue false
  • English
  • Français

Visual evoked potentials in dyslexics and normals: Failure to find a difference in transient or steady-state responses

Published online by Cambridge University Press:  02 June 2009

Jonathan D. Victor ,
Mary M. Conte ,
Leslie Burton  and
Ruth D. Nass
Jonathan D. Victor
Affiliation:
Department of Neurology and Neuroscience, The New York Hospital–Cornell Medical Center, New York Laboratory of Biophysics, The Rockefeller University, New York
Mary M. Conte
Affiliation:
Department of Neurology and Neuroscience, The New York Hospital–Cornell Medical Center, New York Laboratory of Biophysics, The Rockefeller University, New York
Leslie Burton
Affiliation:
Department of Neurology and Neuroscience, The New York Hospital–Cornell Medical Center, New York
Ruth D. Nass
Affiliation:
Department of Neurology, New York University Medical Center, New York
Get access Rights & Permissions [Opens in a new window]

Abstract

We measured transient and steady-state checkerboard contrast-reversal visual evoked potentials (VEPs) in ten dyslexics, five patient controls, and 11 normals over a range of contrasts and luminances. Latency, amplitude, and phase measurements failed to distinguish the responses of dyslexics from those of normals or patient controls. Decreases in luminance or contrast resulted in an increased latency of the transient VEP in all groups, but these changes also did not distinguish the responses of dyslexics from those of the controls. Response variability was similar in dyslexics and normals, but was increased in subjects with attention deficit-hyperactivity disorder (ADHD). Performance on standardized psychometric testing did differentiate the dyslexics from controls, but did not correlate with VEP responses.

Keywords

DyslexiaMagnocellular pathwayVisual evoked potential

Information

Type
Research Articles
Information
Visual Neuroscience , Volume 10 , Issue 5 , September 1993 , pp. 939 - 946
Copyright
Copyright © Cambridge University Press 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Anderson, T.W. (1958). The generalized T 2 statistic. In An Introduction to Multivariate Statistical Analysis, pp. 101–125. New York: Wiley.Google Scholar
Beery, K. (1982). Revised Administration, Scoring, and Teaching Manual for the Developmental Test of Visual Motor Integration. Cleveland, Ohio: Modern Curriculum Press.Google Scholar
Benton, A. & Hamsler, K. (1976). Multilingual Aphasia Examination. Iowa City, Iowa: University of Iowa.Google Scholar
Chiappa, K.H. (1990). Pattern-shift visual evoked potentials: Methodology. In Evoked Potentials in Clinical Medicine, ed. Chiappa, K.H., pp. 37–109. New York: Raven Press.Google Scholar
Duffy, F. & Geschwind, N. (1987). Dyslexia. Boston, Massachusetts: Little, Brown.Google Scholar
Galaburda, A.M. (1992). Dyslexia. The New England Journal of Medicine (Lett.) 327, 279.Google ScholarPubMed
Lehmkuhie, S., Garzia, R.P., Turner, L. & Baro, J.A. (1992). The effects of uniform field flicker on visual evoked potentials in children with reading disability. Investigative Ophthalmology and Visual Science (Suppl.) 33(4), 718.Google Scholar
Livingstone, M.S., Rosen, G.D., Drislane, F.W. & Galaburda, A.M. (1991). Physiological and anatomical evidence for a magnocellular defect in developmental dyslexia. Proceedings of the National Academy of Sciences of the U.S.A. 88, 7943–7947.CrossRefGoogle ScholarPubMed
Lovegrove, W.J., Garzia, R.P. & Nicholson, S.B. (1990). Experimental evidence for a transient system deficit in specific reading disability. Journal of the American Optometric Association 61(2), 137–146.Google ScholarPubMed
MacGinite, W. (1978). Gates-MacGinite Reading Tests. Chicago, Illinois: The Riverside Publishing Co.Google Scholar
Mast, J. & Victor, J.D. (1991). Fluctuations of steady-state VEPs: Interaction of driven evoked potentials and the EEG. Electroencephalography and Clinical Neurophysiology 78, 389–401.CrossRefGoogle ScholarPubMed
May, J., Lovegrove, W., Martin, F. & Nelson, W. (1991). Patternelicited visual evoked potentials in good and poor readers. Clinical Vision Sciences 6(2), 131–136.Google Scholar
Milkman, N., Schick, G., Rossetto, M., Ratliff, F., Shapley, R. & Victor, J.D. (1980). A two-dimensional computer-controlled visual stimulator. Behavioral Research Methods and Instrumentation 12, 283–292.CrossRefGoogle Scholar
Nass, R. (1991). Developmental dyslexia–an update. In Pediatric Neurology: Behavior and Cognition of the Child with Brain Dysfunction, (Pediatric Adolescent Medicine, Vol. 1) ed. Amir, N., Rapin, I., Branski, D., pp. 164–173. Basel, Switzerland: Karger.CrossRefGoogle Scholar
Shaywitz, S.E., Escobar, M.D., Shaywitz, B.A., Fletcher, J.M. & Makuch, R. (1992). Evidence that dyslexia may represent the lower tail of a normal distribution of reading ability. The New England Journal of Medicine 326, 145–150.CrossRefGoogle ScholarPubMed
Slosson, R. (1991). The Slosson Intelligence Test (revised by R. Nicholson & T. Hipshman) Los Angeles, California: Western Psychological Services.Google Scholar
Stuart, G.W. & Lovegrove, W.J. (1992). Visual processing deficits in dyslexia: Receptors or neural mechanisms? Perceptual and Motor Skills 74, 187–192.CrossRefGoogle ScholarPubMed
Victor, J.D. & Mast, J. (1991). A new statistic for steady-state evoked potentials. Electroencephalography and Clinical Neurophysiology 78, 378–388.CrossRefGoogle ScholarPubMed
Wood, F., Flowers, L., Buchsbaum, M. & Tallal, P. (1991). Investigation of abnormal left temporal functioning in dyslexia through RCBF, auditory evoked potentials, and positron emission tomography. Reading and Writing 3(3–4), 379–393.CrossRefGoogle Scholar