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Current scenario of viral diseases in Turkish poultry industry

  • E. BAYRAKTAR (a1), S. UMAR (a2) (a3), A. YILMAZ (a2), N. TURAN (a2) and H. YILMAZ (a2)...


The Turkish poultry industry has rapidly developed in the last decade. Viral pathogens continue to threaten the industry, causing economic losses worldwide, including Turkey. At present, infectious bronchitis and infectious laryngotracheitis are major challenges, as are, to a lesser extent, avian metapneumovirus, infectious bursal disease, Marek's disease and chicken infectious anaemia. The prevalence and severity of these diseases in Turkish chickens varies depending on environmental and management factors, vaccination strategies and biosecurity measures. In Turkey, infectious bronchitis virus, including vaccine and field strains, were detected in 83.6% (41/49) and 64.2% (9/14) vaccinated broiler and layer flocks, respectively. Virulent and vaccine strains of infectious bursal disease virus were found in 83.5% (1548/1855) of excised bursa Fabricius from vaccinated broilers. Virulent Marek's disease virus was found in 19.93% (120/620) of spleens from vaccinated chickens. Infectious laryngotracheitis virus in commercial poultry and Newcastle disease in backyard chickens have been detected. To date, Newcastle disease and avian influenza virus have not been reported in commercial poultry. Avian metapneumovirus was found in 7.2% (8/110) of the broiler samples. Antibodies to gyrovirus and avian leukosis virus have been detected. Commercial vaccines, such as attenuated, inactivated and vectored vaccines, are being used for prevention and control of viral poultry diseases in Turkey. This review summarises the available information on viral poultry diseases in Turkey. It highlights the need to strengthen surveillance and reporting for diseases and addresses the vaccination practices used in Turkish poultry industry. The future prospects of vaccination and need to empower diagnostic capacity in controlling viral poultry diseases are discussed. The information presented here is aimed at improving research, prevention, and control of poultry diseases for researchers, veterinarians, policy makers and other professions related to poultry industry.


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ARAL, Y., YALCIN, C., CEVGER, Y. and SARIOZKAN, S. (2010) Financial effects of the highly pathogenic influenza outbreaks on the Turkish broiler producers. Poultry Science 89: 1085-1088.
AFONSO, C.L. and MILLER, P.J. (2013) Newcastle disease: progress and gaps in the development of vaccines and diagnostic tools. Developments in Biologicals 135: 95-106.
AKAN, M., İZGÜR, M. and SAREYYÜPOĞLU, B. (2007) Infeksiyöz bursal hastalığının immunofloresan tekniği ile teşhisi. Ankara Ünivesity Veterinary Fakulty Dergesi 54: 177-181.
AKBAY, R., ULKER, M. and ELİBOL, O. (1995) Poultry Consumption Projections and Production Targets. IV. Technical Congress of Agriculture Engineering in Turkey. Republic of Turkey Ziraat Bankası Cultural Publications 26: 771-787.
ALEXANDER, D.J. and SENNE, D.A. (2008) Newcastle disease and other avian paramyxoviruses. In: Dufour-Zavala L, ed. A Laboratory Manual for the Isolation, Identification and characterisation of avian pathogens. 4th ed. Athens, GA: American Association of Avian Pathologists, 135-141.
ALEXANDER, D. (2003) Newcastle disease, other avian paramyxoviruses, and pneumovirus infections, in: SAIF, Y.M., BARNES, H.J., GLISSON, J.R., FADLY, A.M., MCDOUGALD, L.R. & SWAYNE, D. (Eds) Diseases of Poultry, pp. 63-99 (Ames, Iowa State University Press).
ALFONSO-MORALES, A., MARTÍNEZ-PÉREZ, O., DOLZ, R., VALLE, R., PERERA, C.L., BERTRAN, K., FRÍAS, M.T., MAJÓ, N., GANGES, L. and PÉREZ, L.J. (2013) Spatiotemporal Phylogenetic Analysis and Molecular Characterisation of Infectious Bursal Disease Viruses Based on the VP2 Hyper-Variable Region. PloS One 8: e65999.
ALKIE, T.N. and RAUTENSCHLEIN, S. (2016) Infectious bursal disease virus in poultry: current status and future prospects. Veterinary Medicine 7: 9-18.
ANONYMOUS (2014) Republic of Turkey Ministry of Food, Agriculture and Livestock 2016. Annual report, Ankara.
ASHRAF, M.U., MAHMOOD, M.S., RAFIQUE, A., ABBAS, R.Z., IQBAL, Z., YOUNAS, M., SADIQ, S.A., USMAN, M., ASGHAR, M.O. and ISHAQ, M.U. (2017) Factors responsible for the continuous persistence and evolution of low pathogenic avian influenza virus (H9N2). World's Poultry Science Journal 73: 791-802.
BAYON-AUBOYER, M.H., ARNAULD, C., TOQUIN, D. and ETERRADOSSI, N. (2000) Nucleotide sequences of the F, L and G protein genes of two non-A/non-B avian pneumoviruses (APV) reveal a novel APV subgroup. The Journal of General Virology 81: 2723-2733.
BAYRAKTAR, E., UMAR, S., YILMAZ, A.N., FRANZO, G., TUCCIARONE, C.M., CECCHINATO, M., CAKAN, B., IQBAL, M. and YILMAZ, H. (2018) First Molecular Characterisation of Avian Metapneumovirus (aMPV) in Turkish Broiler Flocks. Avian Disease, 62: 425-430.
BIGGS, P.M. and NAIR, V. (2012) The long view: 40 years of Marek's disease research and Avian Pathology. Avian Pathology 41: 3-9.
BOODHOO, N., GURUNG, A., SHARIF, S. and BEHBOUDI, S. (2016) Marek's disease in chickens: a review with focus on immunology. Veterinary Research 47: 119.
BOYNUKARA, B., GULHAN, T., COVEN, F., KİZİROĞLU, İ. and DURMUŞ, A. (2013) Determination of Newcastle disease virus among wild bird populations in lake Van Basin, Turkey. Turkish Journal of Veterinary and Animal Sciences 37: 86-93.
CAVANAGH, D. (2007) Coronavirus avian infectious bronchitis virus. Veterinary Research 38: 281-297.
CECCHINATO, M., CATELLI, E., LUPINI, C., RICCHIZZI, E., CLUBBE, J., BATTILANI, M. and NAYLOR, C.J. (2010) Avian metapneumovirus (AMPV) attachment protein involvement in probable virus evolution concurrent with mass live vaccine introduction. Veterinary Microbiology 146: 24-34.
CECCHINATO, M., CATELLI, E., LUPINI, C., RICCHIZZI, E., PROSPERI, S. and NAYLOR, C.J. (2014) Reversion to virulence of a subtype B avian metapneumovirus vaccine: is it time for regulators to require availability of vaccine progenitors? Vaccine 32: 4660-4664.
CHACÓN, J.L. and FERREIRA, A.J.P. (2009) Differentiation of field isolates and vaccine strains of infectious laryngotracheitis virus by DNA sequencing. Vaccine 27: 6731-6738.
CIBLAK, M.A., HASOKSUZ, M., ESCURET, V., VALETTE, M., GUL, F., YILMAZ, H., TURAN, N., BOZKAYA, E. and BADUR, S. (2009) . Surveillance and oseltamivir resistance of human influenza a virus in Turkey during the 2007-2008 season. Journal of Medical Virology 81: 1645-1651.
COOK, J.K.A., HUGGİNS, M.B., ORBELL, S.J. and SENNE, D.A (1999) Preliminary antigenic characterisation of an avian Pneumovirus isolated from a commercial turkeys in Colorado, USA. Avian Pathology 28: 607-610.
COURTNEY, S.C., SUSTA, L., GOMEZ, D., HINES, N.L., PEDERSEN, J.C., BROWN, C.C., MILLER, P.J. and AFONSO, C.L. (2012) Highly divergent virulent isolates of Newcastle disease virus from the Dominican Republic are members of a new genotype that may have evolved unnoticed for over 2 decades. Journal of Clinical Microbiology 51: 508-517.
COVEN, F., RUTH MANVELL, , ORHAN, G., COVEN, N. and GENC, A. (2004) Yumurtacı Ve Broyler Surulerde Gorulen Newcastle Hastalığı Olgularından Avian Paramyxovirusların İzolasyonu Ve İdentifikasyonu. VI. Ulusal Veteriner Mikrobiyoloji Kongresi. Kongre Ozet Kitabı, 222
DAKMAN, A., GULEC, M., GUNAYDIN, E. and COŞAR, M. (2008) Pathotyping of the Newcastle Disease virus strains isolated from the domestic and wild birds. Etlik Veterinary Mikrobiology Dergesi 19: 19-26.
DAKMAN, A., MUŞTAK, K., KARDOĞAN, O., DİVANOĞLU, Y., BİLGEN, N. and AKAN, M. (2014) Turkiye'de 2013 yılında izole edilen Newcastle Viruslarının Biyolojik, Molekuler ve Filogenetik Tiplendirilmesi. XI. Ulusal Veteriner Hekimleri Mikrobiyoloji Kongresi, 21-24 Eylul Antalya.
FAOSTAT (2016) FAO statistical database, accessed in July 2016.
FENG, M. and ZHANG, X. (2016) Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do? Frontiers in Immunology 7: 624 doi: 10.3389/fimmu.2016.00624.
FRANZO, G., TUCCIARONE, C.M., ENACHE, M., BEJAN, V., RAMON, G., KOUTOULIS, K.C. and CECCHINATO, M. (2017) First Report of Avian Metapneumovirus Subtype B Field Strain in a Romanian Broiler Flock During an Outbreak of Respiratory Disease. Avian Diseases 61: 250-254.
FULLER, C., LÖNDT, B., DIMITROV, K.M., LEWIS, N., VAN BOHEEMEN, S., FOUCHIER, R., COVEN, F., GOUJGOULOVA, G., HADDAS, R. and BROWN, I. (2017) An Epizootiological Report of the Re-emergence and Spread of a Lineage of Virulent Newcastle Disease Virus into Eastern Europe. Transboundary and Emerging Diseases 64: 1001-1007.
GULACTİ, I., EROKSUZ, Y. and BULUT, H. (2007) Outbreak of clinical infectious laryngotracheitis in Turkey. Veterinary Record 160: 554-555.
GUY, J.S. and GARCIA, M. (2008) Laryngotraqueitis, in: SAIF, Y.M., GLISSON, J.R., FADLY, A.M., MCDOUGALD, L.R., NOLAN, L.K. & SWAYNE, D.E. (Eds) Diseases of poultry, pp. 137-152 (Iowa State Press).
HADİMLİ, H., ERGANFİ, O., GULER, L. and UCAN, U.S. (2008) Investigation of Chicken Infectious Anemia Virus Infection by PCR and ELISA in Chicken Flocks. Turkish Journal of Veterinary and Animal Sciences 32: 79-84.
HAN, Z., SUN, C., YAN, B., ZHANG, X., WANG, Y., LI, C., ZHANG, Q., MA, Y., SHAO, Y., LIU, Q., KONG, X. and LIU, S. (2011) A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China. Infection, Genetics and Evolution. Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 11: 190-200.
HERNÁNDEZ, M., TOMÁS, G., HERNÁNDEZ, D., VİLLEGAS, P., BANDA, A., MAYA, L., PANZERA, Y. and PÉREZ, R. (2011) Novel multiplex RT-PCR/RFLP diagnostic test to differentiate low- from highpathogenic strains and to detect reassortant infectious bursal disease virus. Avian Diseases 55:368-374.
HIKMET, U.N. (2008) Genetic analysis of highly pathogenic Avian Influenza A (HPAI) H5N1 viruses isolated from Turkey between 2005 and 2008. Etlik Veteriner Mikrobiyoloji Derg 19: 27-38.
HRISTOVA, M. and SIMEONOV, K.B. (2018) Chicken Infectious Anaemia and Co-Infections. Approaches in Poultry Dairy and Veterinary Sciences 5: 1-2.
JACKWOOD, D.J. and SOMMER-WAGNER, S. (2007) Genetic characteristics of infectious bursal disease viruses from four continents. Virology 365: 369-375.
JACKWOOD, M.W. (2012) Review of infectious bronchitis virus around the world. Avian Diseases 56: 634-641.
KAHYA, S., COVEN, F., TEMELLI, S., EYIGOR, A. and CARLI, T. (2013) Presence of IS/1494/06 genotype-related infectious bronchitis virus in breeder and broiler flocks in Turkey. Ankara University Veterinary Science Journal 60: 27-31.
KAYA, B.I. and AKAN, M. (2018) First report of avian infectious laryngotracheitis infection in broiler breeders in Turkey. Ankara Üniversity Veterinary Fakulty Dergesi 65: 331-334.
LEE, E.H., SONG, M.-S., SHIN, J.-Y., LEE, Y.-M., KIM, C.-J., LEE, Y.S., KIM, H. and CHOI, Y.K. (2007) Genetic characterisation of avian metapneumovirus subtype C isolated from pheasants in a live bird market. Virus Research 128: 18-25.
LUKERT, P.D. and SAİF, Y.M. (2003) Infectious bursal disease, in: SAIF, Y.M., GLISSON, J.R., FADLY, A.M., MCDOUGALD, L.R. & SWAYNE, D.E. (Eds) Diseases of Poultry, 11th Edition, pp. 161-180 ( Iowa State University Press, Ames).
MICHEL, L.O. and JACKWOOD, D.J. (2017) Classification of infectious bursal disease virus into genogroups. Archives of Virology 162: 3661-3670.
MILLER, P.J., DECANINI, E.L. and AFONSO, C.L. (2010) Newcastle disease: evolution of genotypes and the related diagnostic challenges. Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 10: 26-35.
MÜLLER, H., MUNDT, E., ETERRADOSSI, N. and ISLAM, M.R. (2012) Current status of vaccines against infectious bursal disease. Avian Pathology 41: 133-139.
NAEEM, K. and SIDDIQUE, N. (2006) Use of strategic vaccination for the control of avian influenza in Pakistan. Developments in Biologicals 124: 145-150.
NAIR, V. (2018) Spotlight on avian pathology: Marek's disease. Avian Pathology 47: 440-442.
NAYLOR, C.J., WORTHINGTON, K.J. and JONES, R.C. (1997) Failure of maternal antibodies to protect young turkey poults against challenge with turkey rhinotracheitis virus. Avian Diseases 41: 968-971.
OIE (2012) Newcastle disease. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Chapter 2.3.14. international-standard-setting/terrestrial-manual/access-online.
OIE (2016a) Infectious bursal disease. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Chapter 2.3.12. fileadmin/Home/eng/Health standards/tahm/2.03.12 IBD.
OIE (2016b) Marek's Disease in OIE Terrestrial Manual. Accessed Jan 2016 standards/tahm/2.03.13 MAREK DIS.pdf.
ONCEL, T., ALEXANDER, D.J., MANVELL, R.J. and TURE, O. (1997) Characterisation of Newcastle disease viruses isolated from chickens and pigeons in the South Marmara region of Turkey. Avian Pathology 26: 129-137.
ONGOR, H., KARAHAN, M., KALİN, R., BULUT, H. and CETİNKAYA, B. (2010) Detection of avian metapneumovirus subtypesin turkeys using RT-PCR. Veterinary Record 166: 363-366
OU, S.C. and GIAMBRONE, J.J. (2012) Infectious laryngotracheitis virus in chickens. World Journal of Virology 1: 142-149.
OZBELIGIN, S., SEN, A., ULGEN, M., CARLI, K.T., SOMEZ, G. and OZMEN, G. (2001) Diagnosis of Lymphoid Leukosis (LL) by ELISA (Enzyme-Linked Immunosorbent Assay) and MarekÕs Disease (MD) by IF (Immunofluorescence) Test in Chickens. Turkish Journal of Veterinary and Animal Sciences 25: 839-846
OZDEMIR, I. (1992) Current new-castle disease situation in Turkey. Workshop On Avian Paramyxovirus. Proceedings. Rauuschholzhausen, 109-116.July 27-29, Germany
PARRA, S.H.S., NUÑEZ, L.F.N. and FERREİRA, A.J.P. (2016) Epidemiology of Avian Infectious Laryngotracheitis with Special Focus to South America: an update Brazilian Journal of Poultry Science 18: 551-562
PAYNE, L.N. and NAIR, V. (2012) The long view: 40 years of avian leukosis research. Avian Pathology 41: 11-19.
PUSCH, E.A. and SUAREZ, D.L. (2018) . The Multifaceted Zoonotic Risk of H9N2 Avian Influenza. Veterinary Sciences 5: 82 doi: 10.3390/vetsci5040082.
SAMJI, T. (2009) Influenza A: understanding the viral life cycle. The Yale Journal of Biology and Medicine 82: 153-159.
SCHAT, K.A. (2009) Chicken anaemia virus. Current Topics in Microbiology and Immunology 331: 151-183.
SNOECK, C.J., OWOADE, A.A., COUACY-HYMANN, E., ALKALI, B.R., OKWEN, M.P., ADEYANJU, A.T., KOMOYO, G.F., NAKOUNÉ, E., LE FAOU, A. and MULLER, C.P. (2013) High genetic diversity of Newcastle disease virus in poultry in West and Central Africa: cocirculation of genotype XIV and newly defined genotypes XVII and XVIII. Journal of Clinical Microbiology 51: 2250-2260.
SWAYNE, D.E., PAVADE, G., HAMILTON, K., VALLAT, B. and MIYAGISHIMA, K. (2011) Assessment of national strategies for control of high-pathogenicity avian influenza and low-pathogenicity notifiable avian influenza in poultry, with emphasis on vaccines and vaccination. Revue Scientifique Et Technique (International Office of Epizootics) 30: 839-870.
TOFFAN, A., TERREGINO, C., MAZZACAN, E., CASTALDELLO, I., CAPUA, I. and BONCI, M. (2011) Detection of Chinese Q1 strain of infectious bronchitis virus in Europe. The Veterinary Record 169: 212-213.
TUIK (2018) Livestock statistics, hayvancilikapp/hayvancilik.zul Accessed 21 April 2019.
TURAN, N. and YILMAZ, H. (2006) Investigations on the Presence of Antibodies to Avian Leukosis Virus Subgroup-J (ALV-J) in Broiler Breeders and Broilers. Turkish Journal of Veterinary and Animal Sciences 29: 1255-1258
TURE, O. and COVEN, F. (1999) Türkiye'deki Infeksiyöz Bursal Hastalıgı Salgınlarından Çok Virulent Virusların Izolasyonu ve Serotiplendirilmesi. Turkish Journal of Veterinary and Animal Sciences, 23: 243-254.
UMAR, S., MUNIR, M.T., AHSAN, U., RAZA, I., CHOWDHURY, M.R., AHMED, Z. and SHAH, M.A.A. (2017) Immunosuppressive interactions of viral diseases in poultry. World's Poultry Science Journal 73: 121-135.
WEI, L., ZHU, S., YAN, X., WANG, J., ZHANG, C., LIU, S., SHE, R., HU, F., QUAN, R. and LIU, J. (2013) Avian Metapneumovirus Subgroup C Infection in Chickens, China. Emerging Infectious Diseases 19: 1092-1094.
YILMAZ, A., TURAN, N., BAYRAKTAR, E., GUREL, A., CIZMECIGIL, U.Y., AYDIN, O., BAMAC, O.E., CECCHINATO, M., FRANZO, G., TALİ, H.E., CAKAN, B., SAVIC, V., RICHT, J.A. and YILMAZ, H. (2019a) Phylogeny and evolution of infectious bursal disease virus circulating in Turkish broiler flocks. Poultry Science 98: 1976-1984.
YILMAZ, H., ALTAN, E., CIZMECIGIL, U.Y., GUREL, A., OZTURK, G.Y., BAMAC, O.E., AYDIN, O., BRITTON, P., MONNE, I., CETINKAYA, B., MORGAN, K.L., FABURAY, B., RICHT, J.A. and TURAN, N. (2016) Phylogeny and S1 Gene Variation of Infectious Bronchitis Virus Detected in Broilers and Layers in Turkey. Avian Diseases 60: 596-602.
YILMAZ, H., TURAN, N., OZGUR, N.Y., HELPS, C.R. and AKAY, O. (2001) Detection of Chicken Anemia Virus DNA in the Thymus of Naturally Infected Chicks in Turkey Avian Diseases 45: 529-533.
YILMAZ, A., TURAN, N., BAYRAKTAR, E., AYDIN, O., TALI, H.E., CAKAN, B., UMAR, S. and YILMAZ, H. (2019b) Molecular Characterisation and Phylogenetic Analysis of Marek's disease virus Meq Gene in Turkish Poultry Flocks. 5th International Meat congress (24-27 April 2019), Antalya, Turkey.


Current scenario of viral diseases in Turkish poultry industry

  • E. BAYRAKTAR (a1), S. UMAR (a2) (a3), A. YILMAZ (a2), N. TURAN (a2) and H. YILMAZ (a2)...


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