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Effect of high fat diet on artificial oocyte activation following superovulation in mice

Published online by Cambridge University Press:  17 June 2015

Daisuke Yamamoto ,
Toshiyuki Yasui ,
Chika Kobayashi ,
Takane Kitazato ,
Takeshi Iwasa  and
Minoru Irahara
Daisuke Yamamoto
Affiliation:
Graduate School of Health Science, University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
Toshiyuki Yasui*
Affiliation:
Department of Reproductive Technology, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
Chika Kobayashi
Affiliation:
Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
Takane Kitazato
Affiliation:
Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
Takeshi Iwasa
Affiliation:
School of Health Sciences, University of Tokushima, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
Minoru Irahara
Affiliation:
School of Health Sciences, University of Tokushima, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
*
All correspondence to: Toshiyuki Yasui. Department of Reproductive Technology, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan. Tel: +81 88 633 9023. Fax: +81 88 631 2630. E-mail: tosyasui@tokushima-u.ac.jp
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Summary

The aim of the present study was to determine the effects of increased dietary intake and high fat diet (HFD) in mice on artificial oocyte activation by using puromycin or roscovitine. Six-week-old mice were fed as either a control diet group, an increased dietary intake group or an HFD group for 4 weeks. Oocytes were obtained following superovulation and were divided into three treatment groups (no activation treatment, calcium ionophore and puromycin treatment, and calcium ionophore and roscovitine treatment) and were incubated for 4 h. Retrieved oocytes and numbers of oocytes activated as assessed by morphological changes were compared among the three treatment groups. The proportion of degenerated oocytes in HFD mice was significantly higher than that in control diet mice. The rates of activation in oocytes treated with roscovitine were 90.3% in control diet mice, 89.8% in increased dietary intake mice and 67.9% in HFD mice. The rate of activation in oocytes treated with roscovitine in HFD mice was significantly lower than the rates in control diet mice and increased dietary intake mice. The rates of activation in oocytes treated with puromycin were 90.6% in control diet mice, 94.0% in increased dietary intake mice and 71.4% in HFD mice, and the rate of activation in oocytes treated with puromycin in HFD mice was significantly lower than the rates in control diet mice and increased dietary intake mice. HFD-induced obesity deteriorated induction of oocyte activation by roscovitine or puromycin in mice.

Keywords

High fat dietOocyte activationPuromycinRoscovitine
Type
Research Article
Information
Zygote , Volume 24 , Issue 2 , April 2016 , pp. 286 - 292
Copyright
Copyright © Cambridge University Press 2015 

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References

Arias-Alvarez, M., Bermejo-Alvarez, P., Gutierrez-Adan, A., Rizos, D., Lorenzo, P.L. & Lonergan, P. (2011). Effect of leptin supplementation during in vitro oocyte maturation and embryo culture on bovine embryo development and gene expression patterns. Theriogenology 75, 887–96.Google Scholar
Bellver, J., Ayllon, Y., Ferrando, M., Melo, M., Goyri, E., Pellicer, A., Remohi, J. & Meseguer, M. (2010). Female obesity impairs in vitro fertilization outcome without affecting embryo quality. Fertil. Steril. 93, 447–54.CrossRefGoogle ScholarPubMed
Bermejo-Alvarez, P., Roberts, R.M. & Rosenfeld, C.S. (2012). Effect of glucose concentration during in vitro culture of mouse embryos on development to blastocyst, success of embryo transfer, and litter sex ratio. Mol. Reprod. Dev. 79, 329–36.CrossRefGoogle ScholarPubMed
Brewer, C.J. & Balen, A.H. (2010). The adverse effects of obesity on conception and implantation. Reproduction 140, 347–64.CrossRefGoogle ScholarPubMed
Cardozo, E., Pavone, M.E., Hirshfeld-Cytron, J.E. (2011). Metabolic syndrome and oocyte quality. Trends Endocrinol. Metab. 22, 103–9.Google Scholar
Carrell, D. (2001). Body mass index is inversely related to intrafollicular HCG concentrations, embryo quality and IVF outcome. Reprod. Biomed. 3, 109–11.Google Scholar
da Silvia Rascado, T., Martins, L.R., Minto, B.W., de Sa Lorena, S.E.R. & da Cruz Landim-Alvarenga, F. (2010). Parthenogenetic development of domestic cat oocytes treated with ionomycin, cycloheximide, roscovitine and strontium. Theriogenology 74, 596–601.Google Scholar
Dokras, A., Baredziak, L., Blaine, J., Syrop, C., Van Voorhis, B.J. & Sparks, A. (2006). Obstetric outcomes after in vitro fertilization in obese and morbidly obese women. Obstet. Gynecol. 108, 61–9.Google Scholar
Fulka, J. Jr., Leibfried-Rutledge, M.L. & First, N.L. (1991). Effect of 6-dimethylaminopurine on germinal vesicle breakdown of bovine oocytes. Mol. Reprod. Dev. 29, 379–84.Google Scholar
Ge, Z.J., Luo, S.M., Lin, F., Liang, Q.X., Huang, L., Wei, Y.C., Hou, Y., Han, Z.M., Schatten, H. & Sun, Q.Y. (2013). DNA methylation in oocytes and liver of female mice and their offspring: effects of high fat diet-induced obesity. Environ. Health Perspect. DOI:10.1289/ehp.1307047 Google ScholarPubMed
Iba, T., Yano, Y., Umeno, M., Hinokio, K., Kuwahara, A., Irahara, M., Yamano, S. & Yasui, T. (2011). Roscovitine in combination with calcium ionophore induces oocyte activation through reduction of M-phase promoting factor activity in mice. Zygote 20, 321–5.Google Scholar
Igosheva, N., Abramov, A.Y., Poston, L., Eckert, J.J., Fleming, T.P., Duchen, M.R. & McConnell, J. (2010). Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes. PLoS One 5, e10074.Google Scholar
Jimenez-Macedo, A.R., Izquierdo, D., Urdaneta, A., Anguita, B. & Paramio, M.T. (2006). Effect of roscovitine on nuclear maturation, MPF and MAP kinase activity and embryo development of prepubertal goat oocytes. Theriogenology 65, 1769–82.CrossRefGoogle ScholarPubMed
Jungheim, E.S., Schoeller, E.L., Marquard, K.L., Louden, E.D., Schaffer, J.E. & Moley, K.H. (2010). Diet-induced obesity model: abnormal oocytes and persistent growth abnormalities in the offspring. Endocrinology 151, 4039–46.Google Scholar
Kubiak, J.Z. (1989). Mouse oocytes gradually develop the capacity for activation during the metaphase II arrest. Dev. Biol. 136, 537–45.Google Scholar
Leroy, J.L., Van Hoeck, V., Clemente, M., Rizos, D., Gutierrez-Adan, A., Van Soom, A., Uytterhoeven, M. & Bols, P.E. (2010). The effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality. Hum. Reprod. 25, 768–78.CrossRefGoogle ScholarPubMed
Lu, Q., Zhao, Y., Gao, X., Li, Y., Ma, S., Mullen, S., Critser, J.K. & Chen, Z.J. (2006). Combination of calcium ionophore A23187 with puromycin salvages human unfertilized oocytes after ICSI. Eur. J. Obstet. Gynecol. Reprod. Biol. 126, 72–6.Google Scholar
Ludgero-Correia, A., Aguila, M.B., Mandarim-de-Lacerda, C.A. & Faria, T.S. (2012). Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL/6 mice. Nutrition 28, 316–23.Google Scholar
Meijer, L. & Kim, S.H. (1997). Chemical inhibitors of cyclin-dependent kinase. Methods Enzymol. 283, 113–28.Google Scholar
Metwally, M., Tuckerman, E.M., Laird, S.M., Ledger, W.L. & Li, T.C. (2007). Impact of high body mass index on endometrial morphology and function in the peri-implantation period in women with recurrent miscarriage. Reprod. Biomed. Online 14, 328–34.CrossRefGoogle ScholarPubMed
Minge, C.E., Bennett, B.D., Norman, R.J. & Robker, R.L. (2008). Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality. Endocrinology 149, 2646–56.Google Scholar
Murase, Y., Araki, Y., Mizuno, S., Kawaguchi, C., Naito, M., Yoshizawa, M. & Araki, Y. (2004). Pregnancy following chemical activation of oocytes in a couple with repeated failure of fertilization using ICSI: case report. Hum. Reprod. 19, 1604–7.Google Scholar
Nakagawa, K., Yamano, S., Moride, N., Yamashita, M., Yoshizawa, M. & Aono, T. (2001a). Effect of activation with Ca ionophore A23187 and puromycin on the development of human oocytes that failed to fertilize after intracytoplasmic sperm injection. Fertil. Steril. 76, 148–152.CrossRefGoogle ScholarPubMed
Nakagawa, K., Yamano, S., Nakasaka, H., Hinokio, K., Yoshizawa, M. & Aono, T. (2001b). A combination of calcium ionophore and puromycin to produce haploid parthenogenones with one haploid pronucleus. Zygote 9, 83–8.Google Scholar
Nakasaka, H., Yamano, S., Hinokio, K., Nakagawa, K., Yoshizawa, M. & Aono, T. (2000). Effective activation method with A23187 and puromycin to produce haploid parthenogenones from freshly ovulated mouse oocytes. Zygote 8, 203–8.CrossRefGoogle ScholarPubMed
Prochazka, R., Durnford, R., Fiser, P.S. & Marcus, G.J. (1993). Parthenogenetic development of activated in vitro matured bovine oocytes. Theriogenology 39, 1025–32.Google Scholar
Robker, R.L. (2008). Evidence that obesity alters the quality of oocytes and embryos. Pathophysiology 15, 115–21.CrossRefGoogle ScholarPubMed
Salha, O., Dada, T. & Sharma, V. (2001) Influence of body mass index and self-administration of hCG on the outcome of IVF cycles: a prospective cohort study. Hum. Fertil. 4, 37–42.Google Scholar
Santos, J.E.P., Bilby, T.R., Thatcher, W.W., Staples, C.R. & Silvestre, F.T. (2008). Long chain fatty acids of diet as factors influencing reproduction in cattle. Reprod. Domest. Anim. 43, 23–30.Google Scholar
Shalom-Paz, E., Marzal, A., Wiser, A., Almog, B., Reinblatt, S., Tulandi, T. & Holzer, H. (2011). Effects of different body mass induces on in vitro maturation in women with polycystic ovaries. Fertil. Steril. 96, 336–9.Google Scholar
Spandorfer, S.D., Kump, L., Goldschlag, D., Brodkin, T., Davis, O.K. & Rosenwaks, Z. (2004). Obesity and in vitro fertilization: negative influences on outcome. J. Reprod. Med. 49, 973–7.Google Scholar
van Swieten, E.C., van der Leeuw-Harmsen, L., Bading, E.A. & van der Linden, P.J. (2005). Obesity and clomiphene challenge test as predictors of outcome of in vitro fertilization and intracytoplasmic sperm injection. Gynecol. Obstet. Invest. 59, 220–4.Google Scholar
Ware, C.B., Barnes, F.L., Maiki-Lauria, M. & First, N.L. (1989). Age dependence of bovine oocyte activation. Gamete Res. 22, 265–75.CrossRefGoogle ScholarPubMed
Wonnacott, K.E., Kwong, W.Y., Hughes, J., Salter, A.M., Lea, R.G., Garnsworthy, P.C. & Sinclair, K.D. (2010). Dietary omega-3 and -6 polyunsaturated fatty acids affect the composition and development of sheep granulose cells, oocytes and embryos. Reproduction 139, 57–69.Google Scholar