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Metastatic cutaneous squamous cell carcinoma of the external ear: a high-risk cutaneous subsite

Published online by Cambridge University Press:  24 September 2009

S J Turner ,
G J Morgan ,
C E Palme  and
M J Veness
S J Turner
Affiliation:
Head and Neck Cancer Service, Westmead Hospital, Sydney, Australia
G J Morgan
Affiliation:
Head and Neck Cancer Service, Westmead Hospital, Sydney, Australia
C E Palme
Affiliation:
Head and Neck Cancer Service, Westmead Hospital, Sydney, Australia Department of Radiation Oncology, University of Sydney, New South Wales, Australia
M J Veness*
Affiliation:
Head and Neck Cancer Service, Westmead Hospital, Sydney, Australia Department of Radiation Oncology, University of Sydney, New South Wales, Australia
*
Address for correspondence: Associate Prof Michael J Veness, Radiation Oncologist, Senior Staff Specialist, Department of Radiation Oncology, Westmead Hospital, Westmead, NSW, Australia2145. Fax: +61 2 989 15814 E-mail: michael.veness@swahs.health.nsw.gov.au
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Abstract

Introduction:

Patients with cutaneous squamous cell carcinoma of the external ear may develop metastatic spread to the nearby ipsilateral parotid and/or upper cervical lymph nodes. The literature suggests that the external ear is a high-risk subsite for such tumours, due to nodal metastasis and its associated morbidity and mortality.

Methods:

Between 1980 and 2007, 43 patients with a diagnosis of metastatic cutaneous squamous cell carcinoma of the external ear were treated with surgery alone, surgery plus adjuvant radiotherapy, or radiotherapy alone.

Results:

Patients comprised 39 men and four women. Their median age at diagnosis was 72 years, with a median follow up of 35 months. The median size of the primary lesion was 21 mm, with a median thickness of 7 mm. Fifteen patients presented concurrently with nodal metastases. Thirty patients developed parotid metastases (with positive cervical nodes in six patients), while 13 developed cervical metastases only. Eight patients underwent surgery alone, 32 underwent surgery plus adjuvant radiotherapy, and three received radiotherapy alone. At the last follow up, 15 patients had relapsed and nine had died of their disease, with a median survival after relapse of 5.5 months.

Conclusion:

Patients with metastatic cutaneous squamous cell carcinoma of the external ear have a relatively poor outcome, with a significant number of patients experiencing nodal relapse and death after treatment.

Keywords

AuricleRadiotherapySkin CancerSquamous Cell Carcinoma
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 1 , January 2010 , pp. 26 - 31
Copyright
Copyright © JLO (1984) Limited 2009

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Footnotes

Presented at the Royal Australasian College of Surgeons and The College of Surgeons of Hong Kong Conjoint Annual Scientific Congress, 12–16 May 2008, Hong Kong, China.

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