1. Introduction
A tremor is defined as an involuntary, rhythmic oscillatory movement of a body part (Bhatia et al., Reference Bhatia, Bain, Bajaj, Elble, Hallett, Louis, Raethjen, Stamelou, Testa and Deuschl2018). While tremulous motion can be observed in most people to a small degree, it is not enough to affect activities of daily living (ADLs). However, pathological conditions may lead to very severe tremulous movements, affecting the quality of life. Such pathological tremors – referred to as tremors in this paper – affects a significant portion of the general population (Louis et al., Reference Louis, Ottman and Hauser1998). Tremor is observed to large extents in wrist flexion-extension (FE) in the 3–12 Hz frequency band with an acceleration amplitude of 13 rad/s2 (Rocon et al., Reference Rocon2004; Pigg et al., Reference Pigg2020). The most prevalent causes of tremor are (i) Parkinson’s disease (PD) and (ii) essential tremor (ET) (Benito-León et al., Reference Benito-León, Bermejo-Pareja, Morales-González, Porta-Etessam, Trincado, Vega and Louis2004, Reference Benito-León, Bermejo-Pareja and Louis2005). While ET affects nearly 5% of the population over 65 years old (Louis, Reference Louis2005), PD affects an estimated 1% of the population over 60 years of age (Elias and Shah, Reference Elias and Shah2014; Benito-Leon, Reference Benito-Leon2018). However, the exact mechanism of the condition is not wholly understood (Bhatia et al., Reference Bhatia, Bain, Bajaj, Elble, Hallett, Louis, Raethjen, Stamelou, Testa and Deuschl2018). The common treatment modalities for patients suffering from such tremors are either surgical or pharmacological. While pharmacological interventions are commonly the first course of action, the efficacy of the treatments appears to diminish over time (Obeso et al., Reference Obeso2017) while also causing secondary effects due to the drugs (Koller and Vetere-Overfield, Reference Koller and Vetere-Overfield1989; Rg et al., 2004). Surgical alternatives are invasive, present a higher risk, and may lead to secondary complications (Piasecki and Jefferson, Reference Piasecki and Jefferson2004; Kleiner-Fisman et al., Reference Kleiner-Fisman, Herzog, Fisman, Tamma, Lyons, Pahwa, Lang and Deuschl2006; Dallapiazza et al., Reference Dallapiazza, Lee, De Vloo, Fomenko, Hamani, Hodaie, Kalia, Fasano and Lozano2019).
As an alternative approach to managing tremulous movements, several wearable devices have been presented. As opposed to pharmacological or surgical interventions, wearable devices suppress the tremor by means of modifying the limb biomechanics. This is achieved by biomechanical loading applied to the limb through a wearable robot (WR) system. Another method to achieve the same biomechanical loading involves the use of functional electrical stimuation (FES) neuroprosthesis (Lora-Millan et al., Reference Lora-Millan, Delgado-Oleas, Benito-León and Rocon2021).
2. Associated challenges
Suppressing tremors using wearable devices adopts two primary approaches. The first approach includes solutions that rely solely on damping forces (Kotovsky and Rosen, Reference Kotovsky and Rosen1998). However, such a passive device can be restrictive to the user. Another approach is to employ WRs by actively managing the tremulous motion (Matsumoto et al., Reference Matsumoto2013; Zhou et al., Reference Zhou, Naish, Jenkins and Trejos2017; Awantha et al., Reference Awantha, Wanasinghe, Kavindya, Kulasekera and Chathuranga2020; Skaramagkas et al., Reference Skaramagkas, Andrikopoulos and Manesis2020). While the tremor attenuation is seen to be effective from the presented results, these WRs are posed with challenges as any WR system that interfaces with a person. The wearable devices utilize either a rigid mechanism (Rocon et al., Reference Rocon2007; Herrnstadt and Menon, Reference Herrnstadt and Menon2016) or soft elements such as cables (Zhou et al., Reference Zhou, Naish, Jenkins and Trejos2017, Reference Zhou, Jenkins, Naish and Trejos2018) and pneumatic actuators (Skaramagkas et al., Reference Skaramagkas, Andrikopoulos and Manesis2020) to effect biomechanical loading and consequently suppress tremulous movements. While the rigid mechanisms enable effective force transmissions, minimizing the misalignment of the robot’s joints with that of the user is crucial (Schiele and Van Der Helm, Reference Schiele and Van Der Helm2006). Additionally, rigid devices often tend to be bulky limiting their wearability and effectiveness in assisting ADLs (Rocon et al., Reference Rocon2007). On the other hand, pneumatic actuators may bring with it a low bandwidth of operation (Wehner et al., Reference Wehner2012) and may cause discomfort due to shear because of a constantly varying area of contact (Davis et al., Reference Davis, Tsagarakis, Canderle and Caldwell2003). Furthermore, cable-driven devices often might need a careful choice of anchor points on the user’s limb to effect appropriate torque (Asbeck et al., Reference Asbeck, De Rossi, Galiana, Ding and James Walsh2014).
Alternatively, wearable devices for FES (Grimaldi et al., Reference Grimaldi, Camut and Manto2011; Bó et al., Reference Bó, Azevedo-Coste, Geny, Poignet and Fattal2014) have shown promising results in suppressing tremulous movements. However major challenges in using FES techniques are first, the timing and control to accurately stimulate the muscles and second, the induced muscle fatigue (Maneski et al., Reference Maneski2011; Heo et al., Reference Heo, Kim, Kwon, Lee, Eom, Kwon, Lee, Park and Manto2015) which may reduce the effectiveness of the devices.
The challenges associated with the development of a tremor suppression system have motivated us to present a WR system utilizing an optimized mechanical metamaterial (MM) as the physical human-robot interface (pHRI) to suppress tremors in wrist FE. MMs are a class of architected structures and mechanisms that derive their properties from the arrangement of the constituent cells (Bertoldi et al., Reference Bertoldi, Vitelli, Christensen and van Hecke2017). As such they offer a large design space that scales combinatorially with the number of cells. This design space can allow for the creation of mechanisms that enable precise and accurate motions like rigid mechanisms while also being conformal like the soft structures. Further utilizing an MM that is optimized to conform to a user’s joint posture and limb trajectory, we then develop a control model using the kinematic data of the user’s limb to effect tremor suppression with the wearable device.
In the following parts of this paper, we will provide an overview of the optimized MM and the wearable device in Section 3.1. Further a description and the modeling of the interaction between the WR with an MM and the user is provided in Section 3.2 along with the tremor suppression approach utilizing the user’s kinematic data. The results of the simulation and testing of the tremor suppression are reported in Section 4. The discussion and conclusion of the contributions of this paper are presented in Sections 5 and 9, respectively.
3. Methods
3.1. An overview of the customized wearable robot
The physical structure of the WR is seen in Figure 1 has two components (i) the pHRI and (ii) a cable-driven actuation.
At the top, the optimized MM is assembled onto the proximal mount to constitute the pHRI. Also highlighted at the top is a unit cell of the MM where
$ {\alpha}_n $
represents the orientation of the axis while the link length
$ {l}_n=\left\Vert {\boldsymbol{A}}_n^{(k)}-{\boldsymbol{B}}_n^{(k)}\right\Vert $
. Two pairs of red and green cables are routed through the spools for the actuation of the MM. When the green cables are in tension the MM bends upwards thus enabling wrist extension. When the red cables are in tension, the MM bends downwards enabling wrist flexion.
3.1.1. Design of the mechanical metamaterial pHRI
The pHRI is composed of an optimized MM. The MM is composed of
$ N=7 $
serially linked cells. Each cell is composed of four rigid links connected at four rotary joints thus constituting a four-bar mechanism as shown in Figure 1. Further, each cell of the MM can be either a bending cell or a planar cell depending on the orientation of the joint axes of the cell. Each cell in the MM is transformed from an initial flat state to another configuration by imparting a stimulus in the form of angular displacement
$ q $
of one link in the cell. Furthermore, the behavior of the cell is dictated by two design variables of the cell which are (i) the length
$ l $
of the constituent links and (ii) the orientation of the cell axis in the initial flat state given as
$ {\alpha}_n=\left[0,\cos {\alpha}_n,\sin {\alpha}_n\right] $
of the cell axis. The link lengths
$ l $
are equal for all the links of a cell and the cell axes are oriented symmetrically about a plane of symmetry (PoS)
$ S $
. Additionally, the cells are connected via ternary links that enable transmission of motion from one cell to the next. The MM has only a single degree of freedom (DOF) irrespective of the number of cells used to constitute the metamaterial.
Finally, the MM can be tuned to follow a desired behavior corresponding to a stimulus by altering the design variables of each cell of the MM. For an application in a WR to assist wrist FE the MM can be tuned to follow the Cartesian trajectory of a fixed point on the user’s hand and also conform to the posture of the user’s wrist. Such a customization can be achieved to minimize the shear between the pHRI and the user’s skin. We have implemented this in a gradient descent-based optimization approach and has already been described in Kulkarni et al. (Reference Kulkarni, Noronha, Campolo and Accoto2021, Reference Kulkarni, Accoto and Campolo2023). Using this approach the optimal parameters of an MM to conform to a specific user’s (29-year-old healthy 95th percentile male) wrist FE is described in Table 1.
Optimized design parameters of an MM with seven cells to assist wrist FE
While we describe the MM designed to fit a specific user in this application, the kinematic model of the MM and the optimization approach developed to generate the design of the MM allow the creation of custom designs for each individual irrespective of their anthropometric class. We direct the reader to Kulkarni et al. (Reference Kulkarni, Accoto and Campolo2023) for more details on the specific cost function used to generate the design of the MM as it is beyond the scope of this paper. This optimisation-based approach enables the development of pHRIs which not only minimize kinematic incompatibility but also minimized shear between the user’s skin and the pHRI for increased comfort.
3.1.2. Actuation of the pHRI
To effect this actuation in a WR setup, we first need a proximal mount which will be used to
-
• Anchor the MM to the user’s hand.
-
• Provide anchor points for the actuating cables.
The MM is mounted to the user with the proximal mount which is designed to allow Velcro straps to anchor the device to the user’s hand. To provide an anchor for the cables actuating the MM, the vertical wall of the proximal mount has four holes placed at appropriate height to accommodate
$ M6 $
cable glands, which will secure the sheath of the Bowden cables to the proximal mount and the actuating cable can pass through to attach to the MM. The spool and cable clamp have been designed to clamp two cables, each of which can provide either
$ q+ $
or
$ q- $
actuation to the MM resulting in a flexion or extension motion respectively. Since cables can only transmit tension, only one pair of these cables will enable actuation at any given point in time as shown in Figure 1. Further, the second spool is designed to be symmetric about
$ S $
to the first spool. On the second spool, the cable enabling
$ q+ $
and
$ q- $
actuation is placed on the opposite side to that of the first spool, thus enabling symmetric actuation of the MM. The two spools are mounted co-axially using a dowel pin and bearings to enable frictionless counter-rotation.
Finally, the MM cells are designed such that the bottom surface of the links reflects the dimensions described in Table 1. Each link of the MM is 15 mm in height to allow for a low profile when worn by the user while still maintaining adequate strength to transmit the forces and torques for assistance. The links of the MM have been designed as parametric parts in Solidworks. This allows for rapid modifications to enable quick design changes. All the parts are produced using fused deposition modeling (FDM) which is an additive manufacturing (AM) process. The links are then assembled using dowel pins as the rotary joints. The wearable part of the actuated MM for supporting wrist FE weighs 350 g on the user’s limb.
To connect the four actuating cables to a motor, we have first developed a multi-level spool consisting of four independent channels to house the cables in. Since the actuating cables are only effective when transmitting tension, any slack in the system would hinder the desired operation of a device. For this reason, a pre-tensioning setup is included as shown in Figure 1. In this setup, pulleys are mounted on platforms which are in turn mounted on lead screws (X-axis feed screw, MISUMI SE Asia). The feed screw setup enables the translation of the pulleys in a direction perpendicular to the cables. The tension in the cable can thus be calibrated by adjusting the position of the feed screw. During assembly, the feed screw was driven using an electric drill to repeatably apply 8 Nm torque and thus tighten each cable to the same tension. The primary goal of this pre-tensioning setup was to ease assembly and remove any slack in the cables before the operation of the device. As such no specific tension goal was set.
For a cable-driven system, the torque transmitted can be determined as a function of the spool diameters at the driving and driven ends as
$$ {\tau}_{\mathrm{m}}={D}_{\mathrm{m}}\frac{\tau_{\mathrm{cmd}}}{D_{\mathrm{MM}}} $$
where
$ {\tau}_{\mathrm{m}} $
is the commanded motor torque,
$ {\tau}_{\mathrm{cmd}} $
is the torque transmitted to the MM at the point of attachment of the driven spool,
$ {D}_{\mathrm{MM}} $
is the diameter of the driven spool and
$ {D}_{\mathrm{m}} $
is the diameter of the spool attached to the motor. For the application of assisting wrist FE, the maximum torque at the wrist is 8 Nm (Morse et al., Reference Morse2006; Yoshii et al., Reference Yoshii2015). To accommodate this within a WR a HEBI X8-9 motor (continuous torque 8 Nm, peak torque 20 Nm) is chosen. Additionally, the diameter of the MM spool
$ {D}_{\mathrm{MM}} $
is chosen to be 80 mm and
$ {D}_{\mathrm{m}} $
to be 48 mm thus providing a mechanical advantage of
$ 1.6 $
. Finally, the choice of the HEBI X8-9 motor is also driven by the fact that these motors are integrated modules (integrated torque sensing).
3.2. Control loop and suppression approach
The interaction forces and torques in the WR system can be visualized as seen in Figure 2. Let us first start with the model of the WR. The goal of this model is to capture the behavior of the robot corresponding to input torque. To describe such a system, we will utilize a 2nd order system. The equation of robot dynamics can be written as.
$$ {I}_{MM}\ddot{q}+{B}_{\mathrm{MM}}\dot{q}={\tau}_{\mathrm{cmd}}+{J}_{\mathrm{MM}}^T\cdot F $$
where
$ {I}_{MM} $
is the inertia of the actuated part of the WR,
$ {B}_{\mathrm{MM}} $
is the friction in the WR system primarily due to the friction of the Bowden cables.
$ {J}_{\mathrm{MM}} $
is the Jacobian of the WR relating the frame of the motor to the frame at the distal mounting point
$ X $
.
$ \boldsymbol{F} $
is the 3
$ \times $
1 vector representing the two forces and a torque at the interface of the distal mount of the WR and the user’s hand. Also,
$ {\tau}_{\mathrm{cmd}} $
is the torque commanded to the motor.
A 3D diagram of the wearable robot with the user’s hand indicating the torques and interaction forces.
Further, the user’s hand can also be modeled as a 2nd order system (Davidson and Charles, Reference Davidson and Charles2017) whose parameters are estimated based on the user’s anthropometric class from the sources (de Leva, Reference de Leva1996; Gomi and Osu, Reference Gomi and Osu1998; Halaki et al., Reference Halaki, O’Dwyer and Cathers2006; Drake and Charles, Reference Drake and Charles2014). As such the equation of the hand and wrist FE dynamics can be written as
$$ {I}_{\mathrm{h}}{\ddot{q}}_{\mathrm{h}}+{B}_{\mathrm{h}}{\dot{q}}_{\mathrm{h}}={\tau}_{\mathrm{int}}-{J}_{\mathrm{h}}^T\cdot \left(F+{F}_{\mathrm{g}}\right) $$
where
$ {I}_{\mathrm{h}} $
and
$ {B}_{\mathrm{h}} $
are the inertia and damping associated with the wrist FE.
$ {\tau}_{\mathrm{int}} $
is the torque generated at the wrist due to voluntary movement by the user which can be estimated using kinematic and biomechanical parameters from Equation 3.3.
$ \boldsymbol{F} $
is the force vector at the distal mount of the WR due to the interaction of the WR with the user and
$ {F}_{\mathrm{g}}={\left[0,0,{\tau}_{\mathrm{g}}\right]}^T $
is a posture-dependent parameter to enable gravity compensation. Additionally the centrifugal force terms have been neglected in Equations 3.2 and 3.3 since we are not dealing with very high velocities in our application.
The interaction of the hand with the WR can be modeled using the mismatch between the frames of the hand and the distal mounting point of the WR. Thus the 2nd order model of the WR is coupled to the 2nd order model of the user’s hand (depicted in Figure 3) as
$$ F={K}_{\mathrm{c}}\left(X-{X}_h\right) $$
where
$ {K}_{\mathrm{c}} $
is a 3
$ \times $
3 diagonal matrix denoting the coupling stiffness between the WR and the user.
$ \boldsymbol{X} $
and
$ {X}_h $
are the frames in 2D Cartesian space of the distal mounting point of the WR and the user’s hand, respectively. These frames can be given by
$$ X=F{K}_{\mathrm{MM}}(q) $$
$$ {X}_h=F{K}_{\mathrm{h}}\left({q}_{\mathrm{h}}\right) $$
A dynamic model of the interaction between the WR using an optimised MM and the user. In the diagram,
$ F={K}_{\mathrm{c}}\cdot \left(X-{X}_h\right) $
. Also
$ X=\left[{x}_{\mathrm{MM}},{z}_{\mathrm{MM}},{\gamma}_{\mathrm{MM}}\right] $
is the frame at the distal mounting point of the MM,
$ {X}_{\mathrm{h}}=\left[{x}_{\mathrm{h}},{z}_{\mathrm{h}},{q}_{\mathrm{h}}\right] $
is the frame at the intended mounting point of the WR on the user’s hand and
$ {K}_{\mathrm{c}} $
is the coupling stiffness between the WR and the user.
$ {\tau}_{\mathrm{cmd}} $
is the torque commanded to the motor and
$ {\tau}_{\mathrm{int}} $
is the torque generated at the joint due to the user’s intent.
While the forward kinematics of the WR have been described in Kulkarni et al. (Reference Kulkarni, Noronha, Campolo and Accoto2021), the forward kinematics of the user’s wrist FE can be computed as a 1 DOF link.
To simulate the functioning and the interaction of the WR and the user, the values of various dynamic parameters such as inertia and damping are to be chosen.
The inertia parameter for the WR is estimated using the complete assembly in Solidworks to be
$ {I}_{\mathrm{MM}}=1e-10\;\mathrm{kg}\hskip0.33em {\mathrm{m}}^2 $
. The damping parameter however is estimated from the description provided in Xiloyannis (Reference Xiloyannis2019)) since the same cables and Bowden sheath are utilized in developing the cable-driven actuation of the WR. This parameter is chosen to be
$ {B}_{\mathrm{MM}}=0.1\;\mathrm{Nms}/\mathrm{rad} $
. The inertia and damping parameters for the wrist FE is gathered from the compilation in Davidson and Charles (Reference Davidson and Charles2017). As such the inertia is chosen to be
$ {I}_{\mathrm{h}}=0.003\;\mathrm{kg}\hskip0.33em {\mathrm{m}}^2 $
and the damping parameter is chosen to be
$ {B}_{\mathrm{h}}=0.028\;\mathrm{Nms}/\mathrm{rad} $
. Additionally, the gravity compensation torque
$ {\tau}_{\mathrm{g}} $
is introduced in the model as a simple specific posture-dependent torque to support the wearer in that posture as
$$ {\tau}_{\mathrm{g}}={m}_{\mathrm{h}}\cdot g\cdot {l}_{\mathrm{h}}\cdot \cos {q}_{\mathrm{h}} $$
where
$ {m}_{\mathrm{h}} $
is the mass of the hand, g is the acceleration due to gravity and
$ {l}_{\mathrm{h}} $
is the distance of the center of gravity of the hand from the wrist FE axis. For the purpose of this simulation, these values have been obtained from a computer aided design (CAD) model of a human forearm and hand with representative anthropometric dimensions. As such
$ {m}_{\mathrm{h}}=0.6\;\mathrm{kg} $
and
$ {l}_{\mathrm{h}}=0.06m $
.
Further, the coupling stiffness between the user’s hand and the WR is estimated to be
$ {K}_{\mathrm{c}}=\operatorname{diag}\left(1000\;\mathrm{N}/\mathrm{m},1000\;\mathrm{N}/\mathrm{m},1000\;\mathrm{N}\mathrm{m}/\mathrm{rad}\right) $
. This coupling stiffness is based on the stiffness of the nylon webbing used at the distal mounting point. The estimation is based on the assumption that all the load transferred to the user through the webbing is by means of longitudinal extension of the webbing. Using the estimated and chosen parameters a model is implemented in Simulink as shown in Figure 4.
The implementation of the viscous damping approach for tremor suppression. This model has been built upon the previously described interaction model of the WR with the user.
3.3. Evaluation and testing of tremor suppression
3.3.1. Simulation
Tremulous movements are composed of two components. First is the voluntary motion component and second is the tremulous component. These motions are seen to be in distinct frequency bands (Rocon et al., Reference Rocon2004). As such, tremulous movements due to Parkinson’s disease and essential tremors are consistently seen to have frequencies >3 Hz while voluntary motion is in the 0–3 Hz band. Further, the amplitude of tremulous acceleration is
$ {a}_{\mathrm{tr}}= $
13
$ \mathrm{rad}/{\mathrm{s}}^2 $
(Rocon et al., Reference Rocon2004). As such tremor is introduced into the simulation as
$$ {\ddot{q}}_{\mathrm{tr}}={a}_{\mathrm{tr}}r(t)\sin \left(2\pi {f}_{\hskip-2pt \mathrm{tr}}t\right) $$
where
$ {f}_{\hskip-2pt \mathrm{tr}} $
is the frequency of the tremulous movement and
$ r(t) $
is a stochastic value between 0 and 1 generated at each time step using a Mersenne Twister Generator with the rand function in Matlab. This is to model the stochastic nature of tremor (Randall, Reference Randall1973; Gantert et al., Reference Gantert, Honerkamp and Timmer1992).
As such to suppress only the tremor and not affect voluntary motions, we can apply a viscous damping torque to the joint based on the frequency of the motion.
To isolate the tremulous motion from the overall motion, the angular velocity of the user’s hand was high-pass filtered (2nd order Butterworth, cut-off frequency 3 Hz) and the tremor suppression torque was commanded using the filtered velocity as
$$ {\tau}_{\mathrm{cmd}}={B}_{\mathrm{s}}\cdot {\dot{q}}_{\mathrm{h}} $$
where
$ {B}_{\mathrm{s}} $
is the viscous damping coefficient chosen to be
$ {B}_{\mathrm{s}}=4\cdot {B}_{\mathrm{h}} $
. This value has been chosen based on the sensitivity analysis presented in Davidson and Charles (Reference Davidson and Charles2017). While higher
$ {B}_{\mathrm{s}} $
values will attenuate tremor more aggressively, the attenuation in the
$ \le $
3 Hz range is also evident and this observation has restricted the choice of
$ {B}_{\mathrm{s}} $
. Further,
$ {\dot{q}}_{\mathrm{h}} $
is the high-pass filtered velocity of the wrist in FE. Furthermore, the choice of
$ {B}_{\mathrm{s}} $
is primarily evaluated using a Bode plot of the controller to ensure that the bandwidth of the designed system spans the tremulous frequency range (3–12 Hz). This evaluation is carried out using the Model Linearizer tool in Simulink.
3.3.2. Test setup
To evaluate the performance of the WR in suppressing the tremor, the setup as shown in Figure 5 is employed. The Mannequin hand is designed such that the various anthropometric dimensions represent the dimensions of the 95th percentile male as described by Tiley and Henry Dreyfuss Associates (Reference Tiley2011). These dimensions are reflective of the specific user the MM has been optimized for.
Test setup for evaluation of the tremor suppression approach using a WR with an optimized MM as the pHRI.
An inertial measurement unit (IMU) is mounted on the hand of the mannequin such that the roll axis of the IMU is parallel to the radial-ulnar deviation (RU) axis of the wrist and the pitch axis to the FE axis of the wrist. The chosen IMU (SparkFun Razor 9DOF) is able to provide accelerometer and gyroscope data at 1 kHz sampling rate. As such the data is low-pass filtered at a cutoff frequency of 100 Hz to eliminate noise. Further, the IMU is also able to natively output Euler angles using the data from the accelerometer and the gyroscope. As such, the data from the IMU along with the data on the orientation of the HEBI motor (also provided natively from the motor) is sufficient to establish the posture of the wrist. This posture aids in providing the appropriate gravity compensation torque. Further, the gyroscope data provides angular velocity measures. As such the gyroscope output of the IMU which is given as a vector
$ [{g}_x,{g}_y,{g}_z] $
in the body-frame of the IMU,
$ {g}_x $
represents the angular velocity about the FE axis, and
$ {g}_y $
represents the angular velocity about the RU axis.
Further, an eccentric mass exciter (EME) is used to inject tremulous motion into the mannequin. The EME is composed of a low current DC motor with a link mounted at the shaft and a mass mounted at the end of the link asymmetrically with respect to (w.r.t) the shaft of the motor to act as the eccentric mass. The excitation force
$ {F}_{\mathrm{tr}} $
provided by the EME can be modeled (Rao, Reference Rao2011) as
$$ {F}_{\mathrm{tr}}= me{\omega}_{\mathrm{tr}}^2\mathit{\sin}{\omega}_{\mathrm{tr}}t $$
where
$ {\omega}_{\mathrm{tr}}=2\unicode{x03C0} {f}_{\hskip-2pt \mathrm{tr}} $
and
$ {f}_{\hskip-2pt \mathrm{tr}}= RP{M}_{\mathrm{tr}}/60 $
. The physical parameters of the EME are eccentric distance
$ e=0.02m $
and eccentric mass
$ m=0.009 kg $
. The voltage–frequency relation of the EME is characterized experimentally using a tachometer and a DC power supply. A linear regression of this data is performed and the coefficients are slope
$ s=6.2248 $
and intercept
$ c=-0.4654 $
to relate the DC voltage to the tremulous frequency
$ {f}_{\hskip-2pt \mathrm{tr}} $
with the equation
$$ {V}_{\mathrm{DC}}=s\cdot {f}_{\hskip-2pt \mathrm{tr}}+c $$
As such, the torque generated by the EME can be computed as
$$ {\tau}_{\mathrm{tr}}={F}_{\mathrm{tr}}\cdot {d}_{\mathrm{tr}} $$
where
$ {d}_{\mathrm{tr}} $
is the distance of the EME axis from the FE axis of the wrist. In the current setup
$ {d}_{\mathrm{tr}}=0.05m $
. Consequently, the simulated tremulous acceleration
$ {a}_{\mathrm{tr}} $
of the hand can be computed as
$$ {a}_{\mathrm{tr}}={I}_{\mathrm{h}}^{-1}\cdot {\tau}_{\mathrm{tr}} $$
Thus the EME enables the generation of a tremulous acceleration amplitude of
$ 13\;\mathrm{rad}/{\mathrm{s}}^2 $
.
Such tremulous motion is injected into the mannequin hand at frequencies of 10, 8, 6, and 4 Hz by controlling the voltage. The tremulous motion caused due to the EME was identified and isolated by performing a high-pass filter with a cutoff frequency of 3 Hz using the Matlab function highpass on the data from the gyroscope
$ {g}_x $
. The filtered velocity
$ {g}_x^f $
is used to command the viscous damping of the tremulous motion.
Further, the HEBI X8-9 motor driving the WR was controlled using the HEBI Matlab API. The data from the motor are sampled at a rate of 1 kHz and low-pass filtered at a cutoff frequency of 100 Hz to eliminate any noise. Additionally, a tremor suppression flag is set to either 0 or 1 based on a user’s input. When the flag is at 0, the tremor suppression does not occur and the WR functions only in gravity compensation mode. While the tremor suppression flag is set to 1, the wearable robot provides viscous damping using the filtered FE velocity
$ {g}_x^{\mathrm{f}} $
in Equation 9 where
$ {\dot{q}}_{\mathrm{h}}={g}_x^{\mathrm{f}} $
.
The test is performed starting at a tremulous excitation frequency of 10 Hz and stepped down to 4 Hz in steps of 2 Hz. Once the tremulous frequency of interest was achieved (by means of voltage control on the DC power supply of the motor according to Equation 3.11) the particular frequency was held for 10 s after which the tremulous frequency was changed to the next step. The WR was operated first in gravity compensation mode and the entire frequency band from 4 Hz to 10 Hz was traversed and the data was recorded using the IMU. Following this, the WR was switched to tremor suppression mode and the test was repeated.
4. Results
The primary metrics for the evaluation of tremor suppression devices are (Lora-Millan et al., Reference Lora-Millan, Delgado-Oleas, Benito-León and Rocon2021).
-
• Peak amplitude of the tremor.
-
• Root mean square (RMS) of the amplitude of tremor.
-
• Power spectral density (PSD).
These metrics provide insight into the nature of the interaction of the WR with the setup.
4.1. Simulation of tremor suppression
From the results of the simulation of tremor at 10 Hz in Figure 6 it can be seen that the adopted approach of damping tremulous motion helps achieve a significant attenuation of tremor. Further, the results of this and other simulations carried out at different frequencies are summarized in Table 2.
Simulation of 10 Hz tremulous motion in Simulink and the associated PSD.
RMS and peak amplitudes of tremor in simulation with and without damping from the WR
Further as seen from the power spectral density in Figure 6 the attenuation is observed to affect only
$ \ge $
3 Hz while the movement below 3 Hz is transmitted without any effect.
4.2. Bench-test of tremor suppression
First a summary of the RMS and peak Table 3. The attenuation of the tremor in both peak and RMS metrics is evident from the results.
RMS and peak amplitudes of tremor with and without damping from the WR in test
Further, the PSD is presented in Figure 7 provides an insight into the nature of the interaction of the WR with the user. While the impact on the interaction in the ≤3 Hz band is minimal (≤1 dB), the attenuation of the tremor is in the range of 20 dB–30 dB depending on the tremor frequency
$ {f}_{\hskip-2pt \mathrm{tr}} $
. Additionally, the impact of the viscous damping in the ≥3 Hz band is evident from the attenuation seen w.r.t the undamped PSD.
A comparative plot of tremulous motion of the mannequin hand at various frequencies with and without viscous damping tremor suppression.
5. Discussion
In this paper, we have presented a method to model the interaction between a WR using an optimised MM as the pHRI and the user. Further, this model has been extended to simulate tremulous motion and a viscous tremor suppression approach has been implemented.
First, on the use of the optimized MM as the pHRI in the WR system. The MM is able to demonstrate complex trajectories that follow the user’s limb despite having a single DOF. This is possible due to the MM’s ability to bend and stretch/contract as it transforms from one state to the other based on the stimulus
$ q $
. This enables the MM to not only conform to the user’s joint posture but also match the strain of the user’s skin thereby minimizing the shear between the pHRI and the user. Furthermore, the developed methodology using a gradient descent-based optimization approach as detailed in our previous publication (Kulkarni et al., Reference Kulkarni, Accoto and Campolo2023) allows the MM to be customized to different users. This approach allows for mechanisms to be generated for each individual based on their anthropometric class. Consequently, the MM can embody the mapping between the trajectory of the user’s limb and the corresponding single stimulus (
$ q $
) needed for the MM to match the user’s current joint state and this mapping is unique to each user. Additionally, the cable-based actuation of the WR allows for the heavier elements of the WR to be placed proximally (e.g., on the waist) allowing for the “worn” part of the WR to be as lightweight as possible. The 350 g weight of the WR mounted on the user’s hand in our case follows within the criterion used in Aubin et al. (Reference Aubin, Sallum, Walsh, Stirling and Correia2014) for the device weight to be ≤40% of the whole hand.
Next, the model of human joint motion as a second-order system is a commonly adopted approach (Pledgie et al., Reference Pledgie2000; Rocon et al., Reference Rocon2004; Taheri et al., Reference Taheri, Case and Richer2011). The second-order model is formulated using acceleration and velocity. These parameters are easily measured using sensors such as inertial measurement units (IMUs) which are composed of accelerometers and gyroscopes. The inertial and damping parameters of the optimized pHRI can be calculated in a similar manner to that presented in Tagliamonte et al. (Reference Tagliamonte2011). Following this, the characterization of the open-loop human–machine model can be undertaken. This can allow for the development of customized and individualized assistance protocols.
Further, the interaction of the WR with the user is through the coupling member (in this case the straps that bind the WR to the user’s hand) the coupling stiffness
$ {K}_{\mathrm{c}} $
used in simulation is only an approximation since the estimation of true
$ {K}_{\mathrm{c}} $
is not a trivial task. The properties of the material used along with the soft-tissue deformation play a significant role in determining the interaction between the pHRI and the user (Wolf et al., Reference Wolf, Miehling and Wartzack2020). Additionally
$ {K}_{\mathrm{c}} $
can be akin to a threshold function where if
$ {K}_{\mathrm{c}} $
is too low, the assistance rendered is insufficient. In the case of this preliminary test and analysis, the choice of
$ {K}_{\mathrm{c}} $
to effect tremor suppression provides a starting point for the development process. However, while applying the device and control strategy to patients the value of
$ {K}_{\mathrm{c}} $
needs to be appropriately characterized within that environment to ensure fundamentally the safety of the patient and additionally the effectiveness of the WR. The development of a robust methodology to estimate biomechanical parameters (
$ {I}_{\mathrm{h}} $
,
$ {B}_{\mathrm{h}} $
) and the coupling stiffness (
$ {K}_{\mathrm{c}} $
) is a necessity.
The tremor suppression approach detailed in this work utilizing only the velocity of the wrist FE
$ {\dot{q}}_{\mathrm{h}} $
is a simple yet effective solution. As shown from the results, the attenuation of the tremor is in the range of 20 dB–30 dB depending on the frequency of the tremor. Furthermore, the choice of viscous damping coefficient
$ {B}_{\mathrm{s}}=4\ast {B}_{\mathrm{h}} $
is driven primarily by the sensitivity analysis presented in Davidson and Charles (Reference Davidson and Charles2017). While such an approach enables the demonstration of potential, a more robust methodology must be adopted to optimize the viscous damping coefficient
$ {B}_{\mathrm{s}} $
to the individual user and their tremor characteristics. Additionally, the usage of graded
$ {B}_{\mathrm{s}} $
based on individual tremor characteristics as opposed to a single value can add to the effectiveness of this approach (Zahedi et al., Reference Zahedi, Arnold and Lee2021).
While the potential of such an approach is evident from the results presented, a true evaluation of the WR and the adopted control methodology is through real-world evaluations. As such conducting clinical evaluations for tremor suppression using this WR would provide a true measure of performance. Such clinical evaluation can include perspectives on the intrusiveness of the WR into the intentional motion and user comfort in addition to tremor suppression. Furthermore, sensing physiological signals such as electromyography (EMG) in addition to kinematic data from the IMU can provide an additional channel of information to estimate the user’s intention more accurately. As such, integration of this sensing modality into the WR control strategy during human-in-loop testing can enable better separation between tremulous movements and intentional movements.
6. Conclusion
In summary, the presented interaction model and the tremor suppression approach demonstrate the potential to warrant a real-world evaluation of the WR. The effectiveness of the WR in suppressing tremor simulated using an EME is evident from the presented results. Additionally, the interaction model as described in Figure 3 can be the first step in developing a multitude of control paradigms for the WR, and the tremor suppression approach serves as a demonstrator for the potential of the interaction model. Further, developing control models can also be done via computational approaches in which a first-level optimization of the MM is done to minimize shear and then a second optimization can be done for the specific control problem.
Data availability statement
The data that support the findings of this study are available from the corresponding author, DC, upon reasonable request.
Authorship contribution
Conceptualization: S.R.K; D.A; D.C. Methodology: S.R.K; D.C. Data visualisation: S.R.K; D.C. Writing original draft: S.R.K; D. A; D.C.. All authors approved the final submitted draft.
Funding statement
The research was conducted with the Future Health Technologies at the Singapore-ETH Centre, which was established collaboratively between ETH Zurich and the National Research Foundation Singapore. This research is partly supported by the National Research Foundation Singapore (NRF) under its Campus for Research Excellence and Technological Enterprise (CREATE) program.
Competing interest
The author declares no competing interests exist.
Ethical standard
The authors declare the research meets all ethical guidelines, including adherence to the legal requirements of the study country.
Open access
