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The use of clostridium botulinum toxin in palatal myclonus. A preliminary report

Published online by Cambridge University Press:  29 June 2007

Shakeel R. Saeed  and
Gerald B. Brookes
Shakeel R. Saeed*
Affiliation:
National Hospital for Neurology and Neurosurgery and The Royal National Throat, Nose and Ear Hospital, London.
Gerald B. Brookes
Affiliation:
National Hospital for Neurology and Neurosurgery and The Royal National Throat, Nose and Ear Hospital, London.
*
Shakeel R. Saeed, F.R.C.S. University Department of Otolaryngology, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
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Abstract

Palatal myoclonus is a rare syndrome characterized by involuntary rhythmical movements of the soft palate giving rise to clicking objective tinnitus. The intrusive nature of the tinnitus prompts patients to seek medical advice but to date no single treatment modality has been shown to be consistently effective. We present three cases in whom various management regimes were unsuccessful and in whom botulinum toxin injection to the palatal muscles was undertaken. All three cases were rendered free of their tinnitus with complete abolition of the myoclonus. The questions of optimum dosage as well as frequency of injection will be answered as greater numbers are treated by this method.

Keywords

Clostridium botulinumMyoclonuspalatal

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 3 , March 1993 , pp. 208 - 210
Copyright
Copyright © JLO (1984) Limited 1993

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References

East, C. A., Hazell, J. W. P. (1987) The suppression of palatal (or intra-tympanic) myoclonus by tinnitus masking devices. A preliminary report. Journal of Laryngology and Otology 101: 1230–1234.CrossRefGoogle ScholarPubMed
Fitzgerald, D. C. (1984) Palatal myoclonus—case report. Laryngoscope 94: 217–219.CrossRefGoogle ScholarPubMed
Lapresle, J. (1979) Rhythmic palatal myoclonus and the dentoolivarpathway. Journal of Neurology 220: 223–230.CrossRefGoogle Scholar
Marsden, C. D., Quinn, N. P. (1990) The dystonias. British Medical Journal 300: 139–144.CrossRefGoogle ScholarPubMed
Moore, A. (1991) Botulinum toxin. Prescribers' Journal, 31: 197–202.Google Scholar
Mountain, R. E., Murray, J. A. M., Quaba, A. (1992) Management of facial synkinesis with Clostridium botulinum toxin injection. Clinical Otolaryngology 17: 223–224.CrossRefGoogle ScholarPubMed
Samant, H. C, Gupta, S. K., Gupta, O. P. (1970) Palatal myoclonus. Annals of Otology, Rhinology, Laryngology 79: 858–861.CrossRefGoogle ScholarPubMed
Siegel, M. A. (1987) Bilateral palatal myoclonus: report of case. Journal of American Dental Association 114: 333–334.CrossRefGoogle ScholarPubMed
Spencer, H. R. (1886) Pharyngeal and laryngeal nystagmus. Lancet 2: 702–704.CrossRefGoogle Scholar