Hostname: page-component-76d6cb85b7-jhrpq Total loading time: 0 Render date: 2026-07-16T12:50:01.829Z Has data issue: false hasContentIssue false

The relationship between self-compassion and depression in young adults: the mediating role of gratitude

Published online by Cambridge University Press:  11 November 2025

Vu Hoang Anh Nguyen
Affiliation:
Head of Clinical Psychologist Unit, Department of Psychosomatic Medicine, Thu Duc City Hospital, Ho Chi Minh City, Vietnam
Ngan-Anh Do-Nguyen*
Affiliation:
Graduate Student, Faculty of Social Sciences and Law, Hoa Sen University, Ho Chi Minh City, Vietnam.
Tran Hoang Duy Le
Affiliation:
PhD Candidate, School of Science, Engineering & Technology, RMIT University Vietnam, Ho Chi Minh City, Vietnam
Rights & Permissions [Opens in a new window]

Abstract

Background

Previous studies have indicated that depression is common among young adults. However, these studies have mainly focused on risk factors rather than protective factors, especially in the context of Vietnam.

Aims

To explore protective factors such as self-compassion and the mediating role of gratitude, crucial for informing targeted interventions aimed at reducing depression in this population.

Method

A cross-sectional study was conducted in September 2023 using convenience sampling of individuals aged 18–25 years (n = 356, mean age 21.23 years) living in Ho Chi Minh City, Vietnam, recruited via online surveys distributed through social networks. The required sample size was determined using Monte Carlo power analysis to ensure adequate statistical power for mediation analysis. Data were analysed to examine the mediating role of gratitude (Gratitude Questionnaire – Six Item Form, GQ-6) in the relationship between self-compassion (Self-Compassion Scale – Short Form, VSCS-SF) and depression (Patient Health Questionnaire-9, PHQ-9).

Results

Self-compassion showed a significant negative association with depression (β = −0.50, t = −11.42, p < 0.001), accounting for 27% of the variance in depression scores. Gratitude significantly mediated this relationship, with an indirect effect of a × b = −0.07 (s.e. = 0.02, 95% CI −0.11 to −0.04]). Specifically, self-compassion positively predicted gratitude (β = 0.34, t = 6.80, p < 0.001), and gratitude, in turn, negatively predicted depression (β = −0.20, t = −4.42, p < 0.001). The direct effect of self-compassion on depression remained significant after controlling for gratitude (β = −0.43, t = −9.52, p < 0.001), indicating a complementary partial mediation. Bootstrap analysis with 5000 resamples further confirmed the robustness of the indirect effect.

Conclusions

The pivotal roles of self-compassion and gratitude in mitigating depression among young adults were explored, informing tailored intervention strategies for mental health practitioners.

Information

Type
Original Article
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NC
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial licence (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists
Figure 0

Fig. 1 The hypothesised model of the relationship between self-compassion and depression, mediated by gratitude.

Figure 1

Table 1 Demographic characteristics of participants (n = 356)Table 1 long description.

Figure 2

Table 2 Means, standard deviations and correlations between variablesTable 2 long description.

Figure 3

Fig. 2 The mediating role of gratitude in the association between self-compassion and depression. ***p < 0.001.

Submit a response

eLetters

No eLetters have been published for this article.