Hostname: page-component-5db58dd55d-jnbmb Total loading time: 0 Render date: 2026-05-25T14:33:31.313Z Has data issue: false hasContentIssue false
  • English
  • Français

Nodular fasciitis: a case series

Published online by Cambridge University Press:  13 June 2008

S D Reitzen ,
S Dogan  and
G Har-El
S D Reitzen*
Affiliation:
Department of Otolaryngology, New York University Medical Center, New York, New York, USA
S Dogan
Affiliation:
Department of Pathology, Lenox Hill Hospital, New York, New York, USA
G Har-El
Affiliation:
Department of Otolaryngology, Lenox Hill Hospital, New York, New York, USA
*
Address for correspondence: Dr Shari D Reitzen, New York University Medical Center, Department of Otolaryngology, 550 First Avenue, NBV 5E5, New York, NY 10016, USA. Fax:  +1 212 434 4222 E-mail: reitzs01@med.nyu.edu
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Given its rarity, varied histological presentation and often pseudosarcomatous appearance, nodular fasciitis is frequently misdiagnosed on pre-operative, intra-operative and final analyses.

Methods:

Four cases of nodular fasciitis are reviewed.

Results:

Physical and radiological findings were consistent with a parapharyngeal tumour, probably neurogenic, a level four neck mass suspicious for lymphoma; a sternoclavicular mass in a patient with a history of breast cancer suspicious for metastasis; and a cheek mass consistent with an accessory parotid tumour. Fine needle aspiration results were consistent with a neurogenic tumour in two patients and an undifferentiated malignancy in two patients. Frozen section examination most commonly included masses with spindle-type cells. The final diagnosis of nodular fasciitis was made only after permanent section and immunohistological analysis.

Conclusions:

In a patient with nonspecific results following investigation of a head or neck mass, nodular fasciitis should be considered. Use of appropriate immunohistochemical markers will aid in the final diagnosis.

Keywords

Nodular FasciitisHead And Neck NeoplasmsSarcoma

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 5 , May 2009 , pp. 541 - 544
Copyright
Copyright © JLO (1984) Limited 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

Footnotes

Presented as a poster at the Head and Neck Society Meeting, Combined Otolaryngologic Spring Meetings, 28 April 2007, San Diego, California, USA.

References

1 Batsakis, JG, Rice, DH, Howard, DR. The pathology of head and neck tumors: spindle cell lesions (sarcomatoid carcinomas, nodular fasciitis, and fibrosarcoma) of the aerodigestive tracts, Part 14. Head Neck Surg 1982;4:499–513CrossRefGoogle ScholarPubMed
2 Dahl, I, Angervall, L. Pseudosarcomatous lesions of the soft tissues reported as sarcoma during a 6-year period (1958–1963). Acta Pathol Microbiol Scand [A] 1977;85:917–30Google ScholarPubMed
3 Montgomery, EA, Meis, JM. Nodular fasciitis: its morphologic spectrum and immunohistochemical profile. Am J Surg Pathol 1991;15:942–8CrossRefGoogle ScholarPubMed
4 Silva, P, Bruce, IA, Malik, T, Homer, J, Banerjee, S. Nodular fasciitis of the head and neck. J Laryngol Otol 2005;119:8–11CrossRefGoogle ScholarPubMed
5 Nishi, SP, Brey, NV, Sanchez, RL. Dermal nodular fasciitis: three case reports of the head and neck and literature review. J Cutan Pathol 2006;33:378–82CrossRefGoogle ScholarPubMed
6 Han, W, Hu, Q, Yang, X, Wang, Z, Huang, X. Nodular fasciitis in the orofacial region. Int J Oral Maxillofac Surg 2006;35:924–7CrossRefGoogle ScholarPubMed
7 Thompson, LD, Fanburg-Smith, JC, Wenig, BM. Nodular fasciitis of the external ear region: a clinicopathologic study of 50 cases. Ann Diagn Pathol 2001;5:191–8CrossRefGoogle ScholarPubMed
8 Matusik, J, Wiberg, A, Sloboda, J, Andersson, O. Fine needle aspiration in nodular fasciitis of the face. Cytopathology 2002;13:128–32CrossRefGoogle ScholarPubMed
9 Kim, ST, Kim, HJ, Park, SW, Baek, CH, Byun, HS, Kim, YM. Nodular fasciitis in the head and neck: CT and MR imaging findings. Am J Neuroradiol 2005;26:2617–23Google ScholarPubMed
10 Kayaselcuk, F, Demirhan, B, Kayaselcuk, U, Ozerdem, OR, Tuncer, I. Vimentin, smooth muscle actin, desmin, S-100 protein, p53, and estrogen receptor expression in elastofibroma and nodular fasciitis. Ann Diagn Pathol 2002;6:94–9CrossRefGoogle ScholarPubMed
11 Dahl, I, Akerman, M. Nodular fasciitis: a correlative cytologic and histologic study of 13 cases. Acta Cytol 1981;25:215–23Google ScholarPubMed
12 DiNardo, LJ, Wetmore, RF, Potsic, WP. Nodular fasciitis of the head and neck in children: a deceptive lesion. Arch Otolaryngol Head Neck Surg 1991;117:1001–2CrossRefGoogle ScholarPubMed