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Global, regional and national burdens of depression in adolescents and young adults aged 10–24 years, from 1990 to 2019: findings from the 2019 Global Burden of Disease study

Published online by Cambridge University Press:  25 April 2024

Cheng-hao Yang
Affiliation:
Department of Vascular Surgery, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China
Jia-jie Lv
Affiliation:
Department of Vascular Surgery, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China; and Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, China
Xiang-meng Kong
Affiliation:
Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, China
Feng Chu
Affiliation:
Department of Vascular Surgery, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China
Zhi-bin Li
Affiliation:
Department of Clinical Psychology, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China
Wei Lu
Affiliation:
Department of Clinical Psychology, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China
Xin-yu Li*
Affiliation:
Department of Vascular Surgery, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, China; and Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, China
*
Correspondence: Xin-yu Li. Email: lixinyu260@sjtu.edu.cn
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Abstract

Background

Depression is a significant mental health concern affecting the overall well-being of adolescents and young adults. Recently, the prevalence of depression has increased among young people. Nonetheless, there is little research delving into the longitudinal epidemiology of adolescent depression over time.

Aims

To investigate the longitudinal epidemiology of depression among adolescents and young adults aged 10–24 years.

Method

Our research focused on young people (aged 10–24 years) with depression, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019. We explored the age-standardised prevalence, incidence and disability-adjusted life-years (DALYs) of depression in different groups, including various regions, ages, genders and sociodemographic indices, from 1990 to 2019.

Results

The prevalence, incidence and DALYs of depression in young people increased globally between 1990 and 2019. Regionally, higher-income regions like High-Income North America and Australasia recorded rising age-standardised prevalence and incidence rates, whereas low- or middle-income regions mostly saw reductions. Nationally, countries such as Greenland, the USA and Palestine reported the highest age-standardised prevalence and incidence rates in 2019, whereas Qatar witnessed the largest growth over time. The burden disproportionately affected females across age groups and world regions. The most prominent age effect on incidence and prevalence rates was in those aged 20–24 years. The depression burden showed an unfavourable trend in younger cohorts born after 1980, with females reporting a higher cohort risk than males.

Conclusions

Between 1990 and 2019, the general pattern of depression among adolescents varied according to age, gender, time period and generational cohort, across regions and nations.

Information

Type
Original Article
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of Royal College of Psychiatrists
Figure 0

Table 1 Prevalence, incidence and disability-adjusted life years of depression in adolescents aged 10–24 years, from 1990 to 2019

Figure 1

Fig. 1 Burden of depression trends in global and five SDI regions for adolescents aged 10–24 years, from 1990 to 2019. SDI, Sociodemographic Index; ASIR, age-standardised incidence rate; ASPR, age-standardised prevalence rate; DALYs, disability-adjusted life-years.

Figure 2

Fig. 2 Maps showing (a) age-standardised prevalence rate, (b) age-standardised incidence rate and (c) age-standardised disability-adjusted life-years rate of depression among adolescents aged 10–24 years, in 204 countries and territories, between 1990 and 2019.

Figure 3

Fig. 3 Change in cases of depression among adolescents aged 10–24 years for both genders, in 204 countries and territories. (a) Change in prevalence cases. (b) Change in incidence cases. (c) Change in disability-adjusted life-years cases.

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