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Prognostic analysis and nomogram prediction model construction of severe full-frequency sudden sensorineural hearing loss

Published online by Cambridge University Press:  08 July 2025

Li Lijuan Open the ORCID record for Li Lijuan [Opens in a new window] ,
Luo Jiasheng ,
Yang Yintong ,
Zhu Guanxia ,
Huo Meixu ,
Zhai Songyu  and
Song Shanghua Open the ORCID record for Song Shanghua [Opens in a new window]
Li Lijuan
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Luo Jiasheng
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Yang Yintong
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Zhu Guanxia
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Huo Meixu
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Zhai Songyu
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
Song Shanghua*
Affiliation:
Department of Otorhinolaryngology - Head and Neck Surgery, Xi’an People’s Hospital (Xi’an Fourth Hospital), Xi’an, SN, China
*
Corresponding author: Song Shanghua; Email: songshanghua1990@163.com
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Abstract

Objectives

This stidy aimed to identify factors influencing prognosis in severe full-frequency sudden sensorineural hearing loss and develop an early prognostic tool.

Methods

A total of 194 patients with severe full-frequency sudden sensorineural hearing loss were analyzed. Univariate analysis screened variables, followed by multivariate logistic regression to construct a nomogram prediction model. Model performance was evaluated using a receiver operating characteristics curve.

Results

Significant differences (p < 0.05) were found between ineffective and effective treatment groups in gender, age, contralateral ear hearing, duration of hearing loss, dizziness/vertigo, hypertension, platelet count and fibrinogen levels (Fib1, Fib2, Fib3). The nomogram model, incorporating these factors, showed good calibration. The receiver operating characteristics curve analysis revealed an area under the curve of 0.880 (95 per cent confidence interval: 0.829–0.931), with sensitivity of 80.7 per cent and specificity of 87.5 per cent.

Conclusion

The nomogram model, integrating 11 factors, effectively predicts prognosis in severe full-frequency sudden sensorineural hearing loss.

Keywords

nomogram predictionprognosisprognostic factorsROC curvesudden sensorineural hearing loss (SSHL)

Information

Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 139 , Issue 9 , September 2025 , pp. 808 - 815
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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Footnotes

Song Shanghua takes responsibility for the integrity of the content of the paper

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