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Vertical partial laryngectomy: our results after treating 81 cases of T2 and T3 laryngeal carcinomas

Published online by Cambridge University Press:  29 June 2007

J. Daniilidis ,
A. Nikolaou ,
G. Fountzilas  and
K. Sombolos
J. Daniilidis*
Affiliation:
Thessaloniki, Greece
A. Nikolaou
Affiliation:
Thessaloniki, Greece
G. Fountzilas
Affiliation:
Thessaloniki, Greece
K. Sombolos
Affiliation:
Thessaloniki, Greece
*
Professor John Daniilidis, M.D., University ENT Clinic, Ahepa Hospital, Thessaloniki 546 36, Greece.
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Abstract

From 1976 to 1989,81 patients with T2 and T3 laryngeal carcinomas were treated with vertical patrial laryngectomy at the University ENT Department of Thessaloniki, Greece. All patients were male with a median age of 56 years (33–71 years). Four patients had N, lymph nodes. Ten patients received post-operative radiotherapy. Seventeen patients developed local recurrences or distant metastases. Mean follow-up was more than seven years. Absolute three-year survival was 94.6 per cent for 74 patients and absolute five-year survival was 89.6 per cent for 58 patients. Actuarial five-year survival of the whole group of 81 patients was 91 per cent calculated with the Kaplan-Meier method. Recurrence rate and survival of stage II and III patients are also discussed and compared using the log-rank test. We conclude that vertical partial laryngectomy is avery successful treatment selection for T2 glottic and false vocal cord carcinomas and for someselected T3 glottic lesions.

Keywords

LaryngectomyLaryngeal neoplasms

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 4 , April 1992 , pp. 349 - 352
Copyright
Copyright © JLO (1984) Limited 1992

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References

Ackerman, L. V., Del Regato, J. A. (1977) Cancer (Diagnosis, treatment and prognosis). 5th edition. The C.V. Mosby Co.: St. Louis, p. 358–377.Google Scholar
Bauer, W. C, Lesinski, S. G., Ogura, J. H. (1975) The significance of positive margins in partial laryngectomy specimens. Laryngoscope, 85: 1–13.CrossRefGoogle Scholar
Daniilidis, J., Nikolaou, A., Symeonidis, V. (1990) Our experience in the surgical treatment of T1 carcinoma of the vocal cord. Journal of Laryngology and Otology, 104: 222–224.CrossRefGoogle ScholarPubMed
Dickens, W. J., Cassisi, N. J., Million, R. R., Bova, F. F. (1983) Treatment of early vocal cord carcinoma: a comparison of apples and apples. Laryngoscope, 93: 216–219.CrossRefGoogle ScholarPubMed
Doyle, P. J., Flores, A., Bell, D. R. (1977) Glottic squamous cell carcinoma (T2): a retrospective study. Annals of Otology, Rhinology and Laryngology, 86: 719–723.CrossRefGoogle ScholarPubMed
Glanz, H., Kimmich, T, Eichhorn, X, Kleinsasser, O. (1989) Behandlungsergebnisse bei 584 Kehlkopfcarcinomen an der Hals—Nasen—Ohrenklinik der Universitat Marburg. HNO Berlin, 37: 1–10.Google ScholarPubMed
Harwood, A. R., Bryce, D. P., Rider, W. D. (1980) Management of T3 glottic cancer. Archives of Otolaryngology, 106: 697–699.Google Scholar
Harwood, A. R., Beale, F. A., Cummings, B. J., Keane, T. J., Rider, W. D. (1981) T2, glottic cancer: an analysis of dose-time-volume factors. International Radiation, Oncology, Biology, and Physics, 7: 1501–1505.Google Scholar
Hoefler, H. (1983) Ergebnisse der CO2- laser-behandlung von Larynxmalignomen. Wien klinische Wochenschrift, 95: 545–547.Google Scholar
Kaplan, H. S., Meier, P. (1958) Non-parametric estimation from incomplete observations. American Statistics Association Journal, 55: 457–480.CrossRefGoogle Scholar
Kelly, D. M., Hahn, S. S., Spaulding, A. C, Kersh, C. R., Cantrell, R. W. (1989) Definitive radiotherapy in the management of stages I and II carcinoma of the glottis. Annals of Otology, Rhinology and Lryngology, 98: 235–239.CrossRefGoogle Scholar
Kennedy, J. X, Crause, C. J. (1974) Survival rates in conservation surgery of the larynx. Archives of Otolaryngology, 99: 274–278.CrossRefGoogle ScholarPubMed
Kessler, D. J., Trapp, T. K., Calcaterra, T. C. (1987) The treatment of T3 glottic carcinoma with vertical partial laryngectomy. Archives of Otolaryngology—Head and Neck Surgery, 113: 1196–1199.CrossRefGoogle ScholarPubMed
Kleinsasser, O. (1987) Tumoren des larynx und des hypopharynx. Georg Thieme Verlag: Stuttgart, New York. p. 178–185.Google Scholar
Lesinski, S. G., Bauer, W. C, Ogura, J. H. (1976) Partial laryngectomy for T3 (fixed cord) epidermoid carcinoma of larynx. Laryngoscope, 86: 1563–1571.CrossRefGoogle Scholar
Mantel, N. (1966) Evaluation of survival data and two new rank order statistics arising in the consideration. Cancer Chemotherapy Reports, 50: 163–170.Google Scholar
Mendenhall, W. M., Million, R. R., Sharkey, D. E., Cassisi, N. J. (1984) Stage T3 squamous cell carcinoma of the glottic larynx treated with surgery and/or radiation therapy. International Journal of Radiation, Oncology, Biology and Physics, 10: 357–363.CrossRefGoogle ScholarPubMed
Million, R. R., Cassisi, N. J. (1984) Larynx. In Management of Head and Neck Cancer. A Multi-disciplinary approach. (Million, R. R., Cassisi, N. J.n eds.). J. B. Lippincott Co.: Philadelphia, p. 316–364.Google Scholar
Ogura, J. H., Biller, H. (1969) Conservation surgery in cancers of the head and neck. Otolaryngologic Clinics of North America, 2: 641.CrossRefGoogle Scholar
Ogura, J. H., Sessions, D. G., Spector, G. J. (1975) Analysis of surgical therapy for epidermoid carcinoma of the laryngeal glottis. Laryngoscope, 85: 1522–1530.CrossRefGoogle ScholarPubMed
Peto, R., Pike, M. C, Armitage, P., Breslow, N. E., Cox, R. R., Howard, S. V., McPherson, K., Peto, J., Smith, P. G. “Design and Anaysis of Randomised Clinical Trials Requiring prolonged observation of each patient: II Analysis and Examples”, Br J Cancer (1977) 35, 1.Google Scholar
Sessions, D. G., Ogura, J. H., Fried, M. P. (1975) The anterior commissure on glottic carcinoma. Laryngoscope, 85: 1624–1632.CrossRefGoogle ScholarPubMed
Silver, C. E. (1981) Surgery for cancer of the larynx and related structures. Churchill Livingstone Inc.: New York. p. 83–121.Google Scholar
Stalpers, L. J., Verbeek, A. L., Van Daal, W. A. (1989) Radiotherapy or surgery for T2 N0 M0 glottic carcinoma. A desicion—analytic approach. Radiotherapy Oncology, 14: 209–217.Google Scholar