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Determinants of residual dizziness in benign positional paroxysmal vertigo patients after effective repositioning manoeuvres: the mediating role of blood lipid levels in a single-centre analysis

Published online by Cambridge University Press:  04 November 2024

Guanyu Wang Open the ORCID record for Guanyu Wang [Opens in a new window]
Guanyu Wang*
Affiliation:
Department of Otolaryngology, Tangshan Eye Hospital, Hebei Province, China
*
Corresponding author: Guanyu Wang; Email: wangguanyu1978@163.com
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Abstract

Objectives

The aim of this study is to identify risk factors for residual dizziness in benign paroxysmal positional vertigo patients after repositioning manoeuvres and explore the mediation role of lipid indicators.

Methodology

In all, 110 benign paroxysmal positional vertigo patients treated from January 2019 to February 2022 were studied. Data on demographics, diseases, behaviours, and lipids were collected. Multivariate logistic regression assessed risk factors, and mediation analyses explored effects via lipid indicators. Odds ratios and 95 per cent confidence intervals are reported.

Results

Differences between groups with and without residual dizziness included limb weakness, hypertension, nausea, arteriosclerosis, medication, dizziness handicap inventory scores, hospital anxiety and depression scale scores, and lipid distributions (p < 0.05). Significant risk factors were sleep disorders, medication, hypertension, triglycerides, and total cholesterol (p < 0.05). Total cholesterol mediated 9.1 per cent of the effect of sleep disorders on residual dizziness.

Conclusion

Managing lipid levels and sleep disorders is crucial in treating residual dizziness in benign paroxysmal positional vertigo patients after repositioning.

Keywords

vertigopostural balanceevidence-based medicine

Information

Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 139 , Issue 5 , May 2025 , pp. 339 - 344
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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Footnotes

Guanyu Wang takes responsibility for the integrity of the content of the paper

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