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Stria vascularis and vestibular dark cells: characterisation of main structures responsible for inner-ear homeostasis, and their pathophysiological relations

Published online by Cambridge University Press:  23 June 2008

R R Ciuman
R R Ciuman*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Tübingen, Germany
*
Address for correspondence: Dr R R Ciuman, Uranusbogen 15,45478 Mülheim, Germany. E-mail: ciuman.raphael@cityweb.de
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Abstract

The regulation of inner-ear fluid homeostasis, with its parameters volume, concentration, osmolarity and pressure, is the basis for adequate response to stimulation. Many structures are involved in the complex process of inner-ear homeostasis. The stria vascularis and vestibular dark cells are the two main structures responsible for endolymph secretion, and possess many similarities. The characteristics of these structures are the basis for regulation of inner-ear homeostasis, while impaired function is related to various diseases. Their distinct morphology and function are described, and related to current knowledge of associated inner-ear diseases. Further research on the distinct function and regulation of these structures is necessary in order to develop future clinical interventions.

Keywords

Inner EarStria VascularisHomeostasisVestibular Diseases

Information

Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 2 , February 2009 , pp. 151 - 162
Copyright
Copyright © JLO (1984) Limited 2008

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