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The prevalence of human papillomavirus in paediatric tonsils in Southwestern Ontario

Published online by Cambridge University Press:  04 October 2021

M Wojtera ,
J W Barrett ,
J E Strychowsky ,
A Dzioba ,
J Paradis ,
M Husein ,
M I Salvadori  and
A C Nichols
M Wojtera
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada
J W Barrett
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
J E Strychowsky*
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
A Dzioba
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
J Paradis
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
M Husein
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
M I Salvadori
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Pediatrics, Western University, London, Ontario, Canada
A C Nichols
Affiliation:
Schulich School of Medicine and Dentistry, London, Ontario, Canada Department of Otolaryngology – Head and Neck Surgery, London, Ontario, Canada
*
Author for correspondence: Dr Julie Strychowsky, Victoria Hospital B3-444, 800 Commissioners Rd East, London, OntarioN6A 5W9, Canada E-mail: julie.strychowsky@lhsc.on.ca Fax: +1 519 685 8185
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Abstract

Objective

To determine the prevalence of human papillomavirus in paediatric tonsils in Southwestern Ontario, Canada.

Materials and methods

Patients aged 0–18 years undergoing tonsillectomy were recruited. Two specimens (left and right tonsils) were collected from each participant. Tonsillar DNA was analysed using quantitative polymerase chain reaction to determine the presence of human papillomavirus subtypes 6, 11, 16 or 18.

Results

A total of 102 patients, aged 1–18 years (mean age of 5.7 years), were recruited. Ninety-nine surveys were returned. There were 44 females (44.4 per cent) and 55 males (55.6 per cent). Forty patients (40.4 per cent) were firstborn children and 73 (73.7 per cent) were delivered vaginally. Six mothers (6.1 per cent) and one father (1.0 per cent) had prior known human papillomavirus infection, and one mother (1.0 per cent) had a history of cervical cancer. All tonsil specimens were negative for human papillomavirus subtypes 6, 11, 16 and 18.

Conclusion

No human papillomavirus subtypes 6, 11, 16 or 18 were found in paediatric tonsil specimens from Southwestern Ontario.

Keywords

Human PapillomavirusHPV Human PapillomavirusTonsilPediatrics
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 3 , March 2022 , pp. 243 - 247
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr J Strychowsky takes responsibility for the integrity of the content of the paper

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