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Use of narrow-band imaging in detection of nasopharyngeal carcinoma

Published online by Cambridge University Press:  02 January 2013

J F Thong ,
D Loke ,
R Karumathil Sivasankarannair  and
P Mok
J F Thong*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
D Loke
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
R Karumathil Sivasankarannair
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
P Mok
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
*
Address for correspondence: Dr Jiun Fong Thong, Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore768828 E-mail: jiunfong@yahoo.com
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Abstract

Aim:

To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.

Method:

Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.

Results:

Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).

Conclusion:

Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

Keywords

NasopharynxEndoscopyAdenoidsImaging, DiagnosticNasopharyngeal CarcinomaDiagnosis

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 2 , February 2013 , pp. 163 - 169
Copyright
Copyright © JLO (1984) Limited 2013

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