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Sinonasal malignancy: presentation and outcomes

Published online by Cambridge University Press:  23 June 2014

Y B Mahalingappa  and
H S Khalil
Y B Mahalingappa
Affiliation:
ENT Department, Plymouth Hospitals NHS Trust, UK
H S Khalil*
Affiliation:
ENT Department, Plymouth Hospitals NHS Trust, UK Plymouth University Peninsula School of Medicine and Dentistry, UK
*
Address for correspondence: Professor Hisham Khalil, ENT Department, Level 7, Derriford Hospital, Plymouth, PL6 8DH, United Kingdom Fax: +44 (0) 175 276 3185 E-mail: hisham.khalil@plymouth.ac.uk
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Abstract

Objective:

We wanted to identify the presentation, diagnostic work-up and treatment outcomes of patients with sinonasal malignancy at Derriford Hospital, Plymouth, UK and compare these with the European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base.

Materials and methods:

This was a retrospective audit of all patients diagnosed with sinonasal malignancy over a five-year period. The clinical records and picture archiving and communications system data of the patients were reviewed.

Results:

Thirty patients with sinonasal malignancy were identified out of 570 head and neck cancer patients. The nasal cavity was the most common site for presentation, followed by the maxillary sinuses. Fifty per cent of patients had a squamous cell carcinoma and 27 per cent had a malignant melanoma. Half of the patients presented at stage IV of the cancer and 20 per cent at stage III. Thirty-seven per cent of patients underwent surgical management and only 20 per cent of the total patient group underwent endoscopic surgery. The mortality in our series was 30 per cent over the studied period.

Conclusion:

Late-stage presentation of sinonasal malignancy has resulted in increased patient mortality in our case series. Also, we found a high incidence of malignant melanoma with high recurrence and survival rates.

Keywords

EndoscopyNose NeoplasmsCarcinoma, Squamous CellMalignant MelanomaPrognosis

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 7 , July 2014 , pp. 654 - 657
Copyright
Copyright © JLO (1984) Limited 2014 

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