Loneliness, while a common human experience, is something to which people often respond quite differently. Here, I examine how an individual’s social position, as well as his socialization into a particular cultural milieu, can shape his response to the fact of his loneliness (as well as the features of human existence that loneliness makes salient). Specifically, I argue that in cases where the individual experiencing loneliness has been socialized to disvalue the features of existence that loneliness makes salient (e.g., our dependence on and vulnerability to others) and/or to feel entitled to the social goods that they are, or perceive themselves to be, lacking (e.g., recognition or intimate connection), loneliness may catalyze the vicious, extremist attitude of ressentiment. This analysis allows us to see how loneliness may play a role in catalyzing vicious, extremist attitudes—though I contend that loneliness never warrants such attitudes.