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Comparison of cocaine alone or with adrenaline on nasal mucosal blood flow

Published online by Cambridge University Press:  29 June 2007

M. J. Porter ,
J. Marais  and
N. Tolley
M. J. Porter*
Affiliation:
London
J. Marais
Affiliation:
London
N. Tolley
Affiliation:
London
*
Mr M. J. Porter, M.A., F.R.C.S., Orsett Hospital, Orsett, Essex, RM16 3EV.
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Abstract

Cocaine is commonly used in ENT practice for its vasoconstrictor and anaesthetic properties. It is sometimes combined with adrenaline. The laser Doppler Flowmeter was used to compare the effect of 5 per cent concaine alone or with adrenaline (1 in 1,000) on nasal mucosal blood flow.

The results show an average fall in blood flow of 76.7 per cent for cocaine with adrenaline, compared to 61.2 per cent with concaine alone. The difference is significant (P<0.05). The time taken for the blood flow to fall was an average of 131 s and 160 s respectively. These differences are not significant.

Keywords

Nasal surgeryCocaineAdrenalineNasal mucosa

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 11 , November 1991 , pp. 918 - 920
Copyright
Copyright © JLO (1984) Limited 1991

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Footnotes

Presented at ORS meeting, Gloucester 19 April 1991

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