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Nasal septal perforation and antiphospholipid syndrome (Hughes syndrome)

Published online by Cambridge University Press:  07 June 2007

S S Banerjee ,
K Lammin  and
J de Carpentier
S S Banerjee*
Affiliation:
Department of Otorhinolaryngology, Royal Preston Hospital, Preston, UK.
K Lammin
Affiliation:
Department of Otorhinolaryngology, Royal Preston Hospital, Preston, UK.
J de Carpentier
Affiliation:
Department of Otorhinolaryngology, Royal Preston Hospital, Preston, UK.
*
Address for correspondence: Miss Sudipta Banerjee, 11 Langham Court, Mersey Road, West Didsbury, Manchester M20 2PX, UK.Fax: 0044 1422 341801 E-mail: sudipta@banerjee.fsnet.co.uk
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Abstract

We present the case of a 19-year-old woman who developed a nasal septal perforation and atrophic rhinitis following septal surgery. During the subsequent five years, she also experienced intermittent episodes of swelling and ischaemia of the left foot, as well as livedo reticularis. Ultimately, haematological investigations revealed the presence of lupus anticoagulant and elevated antiphospholipid immunoglobulin M levels. A diagnosis of antiphospholipid syndrome (Hughes syndrome) was made.

A search of the literature revealed that nasal septal perforation has been described in up to 0.8 per cent of patients with antiphospholipid syndrome. However, it is undescribed in the otorhinolaryngological literature. The impact of this syndrome on otorhinolaryngology practice is examined.

Keywords

Antiphospholipid SyndromeComplications, SurgeryOtorhinolaryngology
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 12 , December 2007 , pp. 1197 - 1200
Copyright
Copyright © JLO (1984) Limited 2007

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