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Nasal craniopharyngioma: case report and literature review

Published online by Cambridge University Press:  24 January 2011

J C Magill ,
M S Ferguson ,
A Sandison  and
P M Clarke
J C Magill*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Charing Cross Hospital, London, UK
M S Ferguson
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Charing Cross Hospital, London, UK
A Sandison
Affiliation:
Department of Histopathology, Charing Cross Hospital, London, UK
P M Clarke
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Charing Cross Hospital, London, UK
*
Address for correspondence: Dr Jennifer C Magill, Department of Otolaryngology – Head and Neck Surgery, Charing Cross Hospital, London W6 8RF, UK Fax:  + 44 (0)208 70 4580775 E-mail: Jennifer_magill22@hotmail.com
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Abstract

Objective:

We report the first case in the English language literature of an adamantinomatous infrasellar craniopharyngioma, and we describe our management strategy.

Case report:

A 46-year-old woman presented with a six-month history of left-sided nasal obstruction and epistaxis. Rhinological examination revealed a left-sided, polypoidal lesion lying medial to the middle turbinate. An urgent examination under anaesthesia was organised; biopsies were considered characteristic of craniopharyngioma. Magnetic resonance imaging and computed tomography demonstrated a well defined, heterogeneous, infrasellar mass centred in the midline, extending anteriorly into the left nasal cavity and posteriorly encasing both internal carotid arteries. Craniofacial resection was performed via a midfacial degloving approach, with adjuvant radiotherapy. The patient was disease-free one year post-operatively.

Conclusion:

Craniopharyngiomas should be considered in the differential diagnosis of a unilateral nasal polyp. Although technically benign, they are locally aggressive. Therefore, we recommend complete excision with adjuvant radiotherapy if margins are involved or close.

Keywords

NosePathologyCraniopharyngioma
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 5 , May 2011 , pp. 517 - 519
Copyright
Copyright © JLO (1984) Limited 2011

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References

1Bunin, GR, Surawitz, TS, Witman, PA, Preston-Martin, S, Davis, F, Bruner, JM. The descriptive epidemiology of craniopharyngioma. J Neurosurg 1998;89:547–51Google Scholar
2Sorva, R, Jaaskinen, J, Heiskanen, O. Craniopharyngioma in children and adults: correlations between radiological and clinical manifestations. Acta Neurochir (Wein) 1987;89:3–9Google Scholar
3Carmel, PW, Antunes, JL, Chang, CH. Craniopharyngiomas in children. Neurosurgery 1982;11:382–9Google Scholar
4Erdheim, J. About hypophyseal adenomas and brain craniopharyngiomas [in German]. Akad Wiss Wein 1904;113:537–726Google Scholar
5Lewin, R, Ruffolo, E, Saraceno, C. Craniopharyngioma arising in the pharyngeal hypophysis. South Med J 1984;77:1519–23Google Scholar
6Cooper, PR, Ransohoff, J. Craniopharyngioma originating in the sphenoid bone: case report. J Neurosurg 1972;36:102–6Google Scholar
7Solarski, A, Panke, ES, Panke, TW. Craniopharyngioma in the pineal gland. Arch Pathol Lab Med 1978;102:490–1Google Scholar
8Byrne, MN, Sessions, DG. Nasopharyngeal craniopharyngioma. Case report and literature review. Ann Otol Rhinol Laryngol 1990;99:633–9CrossRefGoogle ScholarPubMed
9Rodriguez, FJ, Scheithauer, BW, Tsunoda, S, Kovacs, K, Vidal, S, Piepgras, DG. The spectrum of malignancy in craniopharyngioma. Am J Surg Pathol 2007;31:1020–8Google Scholar
10Jiang, RS, Wu, CY, Jan, YJ, Hsu, CY. Primary ethmoid sinus craniopharyngioma: a case report. J Laryngol Otol 1998;112:403–5Google Scholar
11Weiner, HL, Wisoff, JH, Rosenberg, ME, Kupersmith, MJ, Cohen, H, Zagzag, D et al. Craniopharyngiomas: a clinicopathological analysis of factors predictive of recurrence and functional outcome. Neurosurgery 1994;35:1001–11Google Scholar
12Eldevik, OP, Blaivas, M, Gabrielsen, TO, Hald, JK, Chandler, WF. Craniopharyngioma: radiologic and histologic findings and recurrence. AJNR Am J Neuroradiol 1996;17:1427–39Google Scholar
13Manaka, S, Teramoto, A, Takakura, X. The efficacy of radiotherapy for craniopharyngioma. J Neurosurg 1985;62:648–56Google Scholar
14Hetelekidis, S, Barnes, PD, Tao, ML. 20 year experience in childhood craniopharyngiomas. Int J Radiat Oncol Biol Phys 1993;27:189–95Google Scholar