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Effect of passive smoking on ciliary regeneration of nasal mucosa after functional endoscopic sinus surgery in children

Published online by Cambridge University Press:  10 October 2008

A Atef*
Affiliation:
Department of Otolaryngology, Cairo University, Egypt
I Abo Zeid
Affiliation:
Department of Otolaryngology, Cairo University, Egypt
M Qotb
Affiliation:
Department of Otolaryngology, Fayum University, in FayumEgypt
E Gad El Rab
Affiliation:
Department of Pediatrics, Fayum University, in FayumEgypt
*
Address for correspondence: Dr Ahmed Atef, 7 El-Shaheed Mahmoud Afifi Street, Almaza, Cairo, Egypt. E-mail: amratef@dr.com

Abstract

Hypothesis and background:

Passive smoking in the paediatric age group is associated with an increased frequency of a number of childhood respiratory disorders. However, its effect on ciliary regeneration after functional endoscopic sinus surgery for chronic sinusitis has not previously been reported.

Material and methods:

We conducted a prospective, nonrandomised cohort study on 38 paediatric patients with chronic sinusitis. We compared two patient groups – passive smokers and those not subjected to passive smoking – as regards ciliary regeneration after functional endoscopic sinus surgery, using objective methodology.

Results and conclusion:

We found passive smoking to have a negative impact on sinus cilia regeneration following functional endoscopic sinus surgery.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2008

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References

1 Cook, D, Strachan, D. Health effect of passive smoking – 10: summary of effects of parental smoking on the respiratory health of children and implication for research. Thorax 1999;54:357–66Google Scholar
2 Report of the Scientific Committee on Tobacco and Health. London: Department of Health, 1998Google Scholar
3 Smith, T, Mendolia-Loffredo, S, Lochr, LT, Sparpani, R, Laud, P, Nattinger, A. Predictive factors and outcomes in endoscopic sinus surgery for chronic rhinosinusitis. Laryngoscope 2005;115:2199–205CrossRefGoogle ScholarPubMed
4 Briggs, R, Wright, S, Cardes, S, Calhoun, K. Smoking in chronic rhinosinusitis, a predictor of poor long-term outcome after functional endoscopic sinus surgery. Laryngoscope 2004;114:126–8Google Scholar
5 Kim, H, Dhog, H, Chung, S, Chung, Y, Min, J. Prognostic factors of pediatric endoscopic sinus surgery. Int J Pediatr Otorhinolaryngol 2005;69:1535–9CrossRefGoogle ScholarPubMed
6 Melen, I, Lindahl, L, Andreasson, L, Rundcrantz, H. Chronic maxillary sinusitis. Definition, diagnosis and relation to dental infections and nasal polyposis. Acta Otolaryngol (Stockh) 1986;101:320–7CrossRefGoogle ScholarPubMed
7 Stammberger, H, Hawke, M. Essentials of functional endoscopic sinus surgery. Missouri: Mosby Year Book, 1993CrossRefGoogle Scholar
8 Guo, Y, Majima, Y, Hattori, M, Seki, S, Sakakura, Y. Effect of functional endoscopic sinus surgery on maxillary sinus mucosa. Arch Otolaryngol 1997;123:1097–100Google Scholar
9 Bassiouny, A, Atef, A, Abd El Raouf, M, Nasr, S, Nasr, M, Ayad, E. Ultrastructural ciliary changes of maxillary sinus mucosa following functional endoscopic sinus surgery. An image analysis quantitative study. J Laryngol Otol 2003;117:273–9Google Scholar
10 Atef, A, Ayad, E. Ciliary count in chronic suppurative otitis media: a comparative quantitative study between mucosal and squamous types using scanning electron microscopy and image analysis. J Laryngol Otol 2004;118:343–7Google Scholar
11 Aitken, M, Taylor, JA. Prevalence of clinical sinusitis in young children followed up by primary care pediatricians. Arch Pediatr Adolesc Med 1998;152:244–8CrossRefGoogle ScholarPubMed
12 Cunningham, JM, Chiu, EJ, Langraf, JM, Gliklich, RE. The health impact of chronic rhinosinusitis in children. Arch Otolaryngol Head Neck Surg 2000;126:1363–8Google Scholar
13 Lusk, RF, Bothwell, MR, Piccirillo, J. Long-term follow up for children treated with surgical intervention for chronic rhinosinusitis. Laryngoscope 2006;116:2099–107Google Scholar
14 Vandenberg, S, Heatley, D. Efficacy of adenoidectomy in relieving symptoms of chronic sinusitis in children. Arch Otolaryngol Head Neck Surg 1999;123:675–8CrossRefGoogle Scholar
15 Ramadan, H. Adenoidectomy vs endoscopic sinus surgery for the treatment of pediatric sinusitis. Arch Otolaryngol Head Neck Surg 1999;125:1208–11Google Scholar
16 Agius, A, Smallman, L, Pahor, A. Age, smoking and nasal ciliary beat frequency. Clin Otolaryngol 1998;23:227–30CrossRefGoogle ScholarPubMed
17 Vinke, J, Denjan, A, Severijnen, L, Fottens, J. Passive smoking causes an allergic cell infiltrate in the nasal mucosa of non atopic children. Int J Pediatr Otolaryngol 1999;51:7381CrossRefGoogle ScholarPubMed
18 Nageris, B, Hadar, T, Hansen, M. The effect of passive smoking on olfaction in children [in French]. Rev Laryngol Otol Rhinol (Bord) 2002;128:8991Google Scholar
19 Halma, A, Decrelon, S, Bijloos, J, Clement, P. Density of epithelial cells in normal human nose and the paranasal sinus mucosa; a scanning electron microscopy study. Rhinology 1990;28:2532Google Scholar