Hostname: page-component-6766d58669-vgfm9 Total loading time: 0 Render date: 2026-05-25T05:47:23.047Z Has data issue: false hasContentIssue false
  • English
  • Français

Hypersensitive allergic reactions to bismuth-iodoform-paraffin paste following ear surgery

Published online by Cambridge University Press:  29 June 2007

P. V. M. Lim ,
R. G. M. Hughes  and
J. Oates
P. V. M. Lim*
Affiliation:
Department of Otorhinolaryngology, Burton Hospital, Burton-on-Trent, UK.
R. G. M. Hughes
Affiliation:
Department of Otorhinolaryngology, Burton Hospital, Burton-on-Trent, UK.
J. Oates
Affiliation:
Department of Otorhinolaryngology, Burton Hospital, Burton-on-Trent, UK.
*
Address for correspondence: Dr Paul Vey-Hong Lim, Department of Otorhinolaryngology, University of Malaya, University Hospital, Lembah Pantai, 50603 Kuala Lumpur, Malaysia. Fax: 00-6-03-755-6963 email: paul@medicine.med.um.edu.my
Get access Rights & Permissions [Opens in a new window]

Abstract

The case notes of 185 patients who had bismuth-iodoform-paraffin paste (BIPP) impregnated ribbon gauze used for packing following ear surgery were analysed retrospectively. The incidence of hypersensitive allergic reactions to BIPP was 5.9 per cent and a five-fold increase risk of developing allergic reactions was found in those with previous exposure to BIPP. Where temporalis fascia was used to repair tympanic membrane defects, the incidence of tympanic membrane graft perforations was higher when allergic reactions to BIPP developed post-operatively, compared to non-allergic cases.

Keywords

Otitis media, suppurativeTympanoplastyIodineDressingsHypersensitivity

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 4 , April 1998 , pp. 335 - 337
Copyright
Copyright © JLO (1984) Limited 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

REFERENCES

Bousfield, P. (1917) Note on poisoning with bismuth-iodoform-paraffin paste. St Bartholomew's Hospital Journal 25: 4–6.Google Scholar
Colman, G. (1962) A study of some antimicrobial agents used in oral surgery. British Dental Journal 113: 22–28.Google Scholar
Chevretton, E. B., McRae, R. D. R., Booth, J. B. (1991) Mastoidectomy packs: Xeroform or BIPP? Journal of Laryngology and Otology 105: 916–917.CrossRefGoogle ScholarPubMed
Diamond, C, Frew, I. (1979) The Facial Nerve. Oxford University Press, Oxford, p 283.Google Scholar
Farrell, R. W. R. (1994) Dangers of bismuth iodoform paraffin paste. Lancet 344: 1637–1638.CrossRefGoogle ScholarPubMed
Harry, P., Bouachour, G., Tirot, P., Chennebault, J. M., Cailleux, A., Allain, P., Alquier, P. (1992) Toxication a l'iodoforme. Three observations. Journal of Toxicology Clinical Experiments 12: 35–42.Google Scholar
Jones, P. H. (1985) BIPP allergy causing facial paralysis. Journal of Laryngology and Otology 99: 389–390.CrossRefGoogle ScholarPubMed
Jones, J. A. H. (1990) BIPP: a case of toxicity? Oral Surgery, Oral Medicine and Oral Pathology 69: 668–671.CrossRefGoogle ScholarPubMed
Kruger, G., Thomas, D. J., Weinhart, F., Hoyer, S. (1976) Disturbed oxidative metabolism in organic brain syndrome caused by bismuth in skin creams. Lancet 4: 485–487.CrossRefGoogle Scholar
Muir, A. H. (1903) A case of iodoform poisoning. Lancet i: 960.CrossRefGoogle Scholar
Morrison, R. (1916) The treatment of infected suppurating war wounds. Lancet ii: 268–272.CrossRefGoogle Scholar
O'Connor, A. F. F., Freeland, A. P., Heal, D. J., Rossouw, D. S. (1977) Iodoform toxicity following the use of BIPP: A potential hazard. Journal of Laryngology and Otology 91: 903–907.CrossRefGoogle ScholarPubMed
Radden, H. G. (1962) Mouth wounds. British Dental Journal 113: 112–119.Google Scholar
Sharma, R. R., Cast, I. P., Redfern, R. M., O'Brien, C. (1994) Extradural application of bismuth iodoform paraffin paste causing relapsing bismuth encephalopathy: a case report with CT and MRI studies. Journal of Neurology, Neurosurgery and Psychiatry 57: 990–993.CrossRefGoogle ScholarPubMed
Short, A. R. (1910) Iodoform and thyroidism. Medical Press and Circular 2: 309–311.Google Scholar