Hostname: page-component-8448b6f56d-dnltx Total loading time: 0 Render date: 2024-04-24T13:40:24.463Z Has data issue: false hasContentIssue false

Cerebrospinal fluid rhinorrhoea: does fibrin glue change the surgical outcome?

Published online by Cambridge University Press:  16 July 2020

P B Ganesh
Affiliation:
Department of ENT and Head and Neck, JSS Medical College, Mysore, India
B M Basavarajaiah
Affiliation:
Department of ENT and Head and Neck, JSS Medical College, Mysore, India
B A Rudrappa*
Affiliation:
Department of ENT and Head and Neck, JSS Medical College, Mysore, India
S K Kasaragod
Affiliation:
Department of ENT and Head and Neck, JSS Medical College, Mysore, India
*
Author for correspondence: Dr Babu Ambale Rudrappa, Department of ENT and head and neck, JSS Medical College, MG road, Mysore570004, India E-mail: jssent2018@gmail.com

Abstract

Objective

Cerebrospinal fluid rhinorrhoea takes place when there is a breakdown of the barriers separating the nasal cavity from the subarachnoid space. The aim of this study was to assess the surgical outcomes of endoscopic transnasal cerebrospinal fluid leak repair with and without fibrin glue.

Method

There were 43 patients with cerebrospinal fluid rhinorrhoea who underwent surgery for cerebrospinal fluid leak repair between 2014 and 2018. Patients were divided into group A, where fibrin glue was used, and group B, where fibrin glue was not used.

Results

It was found that 74.4 per cent of cases were due to spontaneous cerebrospinal fluid leak. The most common site of a leak was the cribriform plate (65 per cent). There was a success rate of 96.1 per cent (25 of 26) in group A and 83 per cent (15 of 17) in group B. There was no statistically significant difference between the results of the two groups (chi-square test: p = 0.31).

Conclusion

There was no statistically significant difference in the results of cerebrospinal fluid leak repair with and without fibrin glue.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited, 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Dr B A Rudrappa takes responsibility for the integrity of the content of the paper

References

Bachmann, G, Djenabi, U, Jungehülsing, M, Petereit, H, Michel, O. Incidence of occult cerebrospinal fluid fistula during paranasal sinus surgery. Arch Otolaryngol Head Neck Surg 2002;128:1299–302CrossRefGoogle ScholarPubMed
Scott, M Graham. CSF leak. In: Watkinson, JC, Clarke, RW, eds. Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, 8th edn. Boca Raton: CRC Press, 2018;1201–5Google Scholar
Jain, A, Singhal, P, Sharma, MP, Singh, SN, Grover, M. Transnasal endoscopic cerebrospinal fluid rhinorrhea repair: our experience of 35 cases. Clin Rhinol Int J 2014;7:4751Google Scholar
Erkan, AN, Cakmak, O, Kocer, NE, Ylmaz, I. Effects of fibrin glue on nasal septal tissues. Laryngoscope 2007;117:491–6CrossRefGoogle ScholarPubMed
De Almeida, JR, Ghotme, K, Leong, I, Drake, J, James, AL, Witterick, IJ. A new porcine skull base model: fibrin glue improves strength of cerebrospinal fluid leak repairs. Otolaryngol Head Neck Surg 2009;141:184–9CrossRefGoogle ScholarPubMed
Nishihira, S, McCaffrey, TV. The use of fibrin glue for the repair of experimental CSF rhinorrhea. Laryngoscope 1988;98:625–7CrossRefGoogle ScholarPubMed
Zweig, JL, Carrau, RL, Celin, SE, Schaitkin, BM, Pollice, PA, Snyderman, CH et al. Endoscopic repair of cerebrospinal fluid leaks to the sinonasal tract: predictors of success. Otolaryngol Head Neck Surg 2000;123:195201CrossRefGoogle ScholarPubMed
Cassano, M, Felippu, A. Endoscopic treatment of cerebrospinal fluid leaks with the use of lower turbinate grafts: a retrospective review of 125 cases. Rhinology 2009;47:362–8Google ScholarPubMed
Mirza, S, Thaper, A, McClelland, L, Jones, NS. Sinonasal cerebrospinal fluid leaks: management of 97 patients over 10 years. Laryngoscope 2005;115:1774–7CrossRefGoogle ScholarPubMed
Lindstrom, DR, Toohill, RJ, Loehrl, TA, Smith, TL. Management of cerebrospinal fluid rhinorrhea: the Medical College of Wisconsin experience. Laryngoscope 2004;114:969–74CrossRefGoogle ScholarPubMed
Mohindra, S, Mohindra, S, Gupta, K. Endoscopic repair of CSF rhinorrhea: necessity of fibrin glue. Neurol India 2013;61:396–9Google ScholarPubMed
Kirtane, MV, Gautham, K, Upadhyaya, SR. Endoscopic CSF rhinorrhea closure: our experience in 267 cases. Otolaryngol Head Neck Surg 2005;132:208–12CrossRefGoogle ScholarPubMed
McMains, KC, Gross, CW, Kountakis, SE. Endoscopic management of cerebrospinal fluid rhinorrhea. Laryngoscope 2004;114:1833–7CrossRefGoogle ScholarPubMed
Yadav, YR, Parihar, V, Janakiram, N, Pande, S, Bajaj, J, Namdev, H. Endoscopic management of cerebrospinal fluid rhinorrhea. Asian J Neurosurg 2016;11:183–93CrossRefGoogle ScholarPubMed
Schlosser, RJ, Wilensky, EM, Grady, MS, Bolger, WE. Elevated intracranial pressures in spontaneous cerebrospinal fluid leaks. Am J Rhinol 2003;17:191–5CrossRefGoogle ScholarPubMed