We, the Editors of BJPsych, have retracted the following article:

Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study | The British Journal of Psychiatry | Cambridge Core

In October 2025, the authors of this paper voluntarily informed the journal that errors had been identified during analyses of the open-label extension phase of the Ketamine for Adult Depression Study (KADS). Specifically, total HAM-A scores for two participants at the end of the randomised controlled treatment phase and one participant at the four-week after treatment end visit, which should have been coded as ‘missing’, had been incorrectly scored as ‘0’.

The authors repeated all analyses. There were small changes to means, standard deviations, p-values and confidence intervals, but all p-values originally reported as <0.05 remained <0.05, and the overall interpretation and conclusions of the study were unchanged.

The Editors conducted an additional review and agreed that the errors did not alter the study’s findings or final conclusions. However, given the extent of the corrections required, they concluded that a corrigendum would not be sufficient. They agreed that retraction of the original article with subsequent resubmission of a corrected paper would be the best course of action.

All authors have confirmed agreement to the retraction.