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Electrocochleographic findings and the effects of lidocaine on tinnitus in non-hearing ears.

Published online by Cambridge University Press:  29 June 2007

P. Jackson
P. Jackson*
Affiliation:
London
*
Peter Jackson, F.R.C.S., Consultant ENT Surgeon, Greenwich District Hospital, Vanbrugh Hill, London SE10 9HE.
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Abstract

In the preceeding report (Jackson, 1985) the author produced evidence which brought into question the widely held view that, in abolishing tinnitus, lidocaine was acting ‘centrally’. This present investigation is another approach to attempt to narrow the site of action of lidocaine in abolishing tinnitus.

During a four-year period, patients suffering from strictly unilateral tinnitus which was referred to, and therefore apparently arising from, an ipsilateral ‘dead’ ear, underwent electrocochleography. Additionally, the subjective effect on the tinnitus of a bolus injection of lidocaine was recorded. Nine patients were available for this study, which appears to show a correlation of the results of the elec-trocochleogram and the effects of the lidocaine injection, although the numbers are small.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 99 , Issue 7 , July 1985 , pp. 667 - 670
Copyright
Copyright © JLO (1984) Limited 1985

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References

Donaldson, I. (1978) Tinnitus: A theoretical view and a therapeutic study using amylobarbitone. Journal of Laryngology and Otology, 92: 123–130.CrossRefGoogle Scholar
Donaldson, I. (1981) Tegretol: A double blind trial in tinnitus. Journal of Laryngology and Otology, 95: 947–950.CrossRefGoogle ScholarPubMed
Emmett, J. R. and Shea, J. J. (1980) Treatment of tinnitus with tocainide hydrochloride. Otolaryngology, Head and Neck Surgery, 88: 442–446.Google Scholar
Englesson, S., Larsson, B., Lindquist, N., Lyttkens, L. and Stahle, J. (1976) Accumulation of 14C-lidocaine in the inner ear. Acta Oto-Latyngologica 82: 297–300.CrossRefGoogle ScholarPubMed
Evans, E. F. (1981) Animal models of tinnitus. Tinnitus Ciba Foundation Symposium, 85: 108–130. Pitman.Google Scholar
Galambos, R. (1956) Suppression of Auditory Nerve Activity by Stimulation of Efferent Fibres to the Cochlea. Journal of Neurophysiology, 19: 424–437.Google Scholar
Gejrot, T. (1976) Intravenous xylocaine in the treatment of attacks of Menière's disease. Acta Otolaryngologia, 82: 301–302.CrossRefGoogle ScholarPubMed
Gibson, W. P. R. (1978) Essentials of clinical electric response audiometry. Chapter 4, Churchill Livingstone.Google Scholar
Gibson, W. P. R. (1983) Personal communication.Google Scholar
Hazell, J. W. P. (1979) Tinnitus. British Journal of Hospital Medicine, 22: 468–471.Google Scholar
Jackson, P. D. (1985) Tinnitus: the effects of VIII nerve section and of intravenous lidocaine. Journal of Laryngology and Otology, 99: 663–666CrossRefGoogle Scholar
Kemp, D. T. (1978) Stimulated acoustic emissions from within the human auditory system. Journal of the Acoustical Society of America, 64: 1386–1391.Google Scholar
Marks, N. J., Onisphorou, C. and Trounce, J. R. (1981) The effects of single doses of amylobarbitone sodium and carbamezapine in tinnitus. Journal of Laryngology and Otology, 95: 941–945.CrossRefGoogle Scholar
Melding, P. S., Goodey, R. J. and Thorne, P. R. (1978) The use of intravenous lignocaine in the diagnosis and treatment of tinnitus. Journal of Laryngology and Otology, 92: 115–121.Google Scholar
Melding, P. S. and Goodey, R. J. (1979) The treatment of tinnitus with oral anticonvulsants. Journal of Laryngology and Otology, 93: 111–122.Google Scholar
Sakata, E., Umeda, Y., Takahashi, K. and Ohtsu, K. (1976) Treatment of the cochlear tinnitus—Blocking therapy with 4 per cent lidocaine. Journal of Otolaryngology of Japan, 79, part 7: 741–746.Google Scholar
Shea, J. J. (1979) Clinical experience with praxilene, mysoline and tegretol therapy and tinnitus control. Paper read at 1st international tinnitus seminar New York, 06 1979.Google Scholar
Ward, P. H. and Honrubia, V. (1969) Cochlear potentials. Recruitment produced by local anaesthetics. Surgical Forums, 17: 470–471.Google Scholar
Wiederhold, M. L. and Kiang, N. (1970) Effects of Electrical Stimulation of the crossed olivocochlear bundle on single auditory nerve fibres in the cat. Journal of the Acoustical Society of America, 48: 950–965.Google Scholar