Overview

Multidisciplinary efforts have begun to encourage a freer exchange of information – resulting in a more ‘integrative neuroscience’ across disciplines and theoretical models in psychiatry. This symposium outlines the potential insights into major psychiatric disorders from the first entirely standardized and centralized database, which brings together cognitive, affective, brain function and genetic measures. It contains 5000 healthy subjects (6–100 years) and growing psychiatric groups. With these multimodal and standardized data sets, we have identified objective markers that distinguish each disorder and that predict real-life functional outcomes. In this symposium, we outline markers for first-episode schizophrenia, attention deficit hyperactivity disorder, depression and Alzheimer's dementia.