Published online by Cambridge University Press: 19 December 2019
To provide an effective infection specialist service, practitioners must be conversant in pre-analytical, analytical and post-analytical elements of laboratory practice, irrespective of the specific areas of infectious diseases undertaken on a day-to-day basis. Pre-analytical skills and knowledge will include areas such as understanding the microbial differential diagnoses sufficiently to advise on and obtain the correct tests on the optimal sample types, be this for culture or for serological or genetic diagnostic tests. Pre-analytical skills also help practitioners identify where tests will not aid diagnosis, including for conditions which are currently diagnosed clinically and for which laboratory diagnostics do not currently exist. Analytical skills and understanding will vary depending on the area of practice, but will include safe laboratory work, the strengths and limitations of different tests, the impact of quality assurance and quality control and the cost implications of different modalities. Post-analytical skills and understanding will include contextualisation of results in each patients’ care, awareness of positive and negative predictive values of different tests and implications for further diagnostics including reflex testing.
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